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- Tasks: Lead innovative biotherapeutic discovery through strategic screening and functional assay development.
- Company: Join AbbVie, a leader in innovative medicines tackling serious health challenges across multiple therapeutic areas.
- Benefits: Enjoy comprehensive benefits including paid time off, medical insurance, and participation in incentive programs.
- Why this job: Be part of a dynamic team driving transformative ideas to the clinic while fostering collaboration and innovation.
- Qualifications: Requires a BS/MS/PhD in Biology with extensive experience in biotherapeutic discovery and screening.
- Other info: AbbVie values diversity and is committed to equal opportunity in employment.
The predicted salary is between 48000 - 84000 £ per year.
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio.
Discovery Biotherapeutics and Genetic Medicine (BGM) at AbbVie is seeking a highly motivated Principal Research Scientist to join the Cell and Functional Biology group at the AbbVie Bioresearch Center (ABC) site based in Worcester, MA. This role will be responsible for the design and execution of screening strategies employed to advance promising biotherapeutics from early exploration through lead optimization. Close partnerships with cross-functional colleagues will be required to drive transformative ideas to the clinic. The ideal candidate should possess experience in large molecule screening strategy design including in vitro cell-based assays, with strong experience in functional assay development and high-throughput screening.
Job Responsibilities:
- Develop in vitro functional assays leveraging diverse signaling pathways to transition early therapeutic ideas into enabled biotherapeutics campaigns.
- Design and employ strategic screening funnels for biotherapeutic discovery campaigns, performing detailed analysis of complex data sets for key insights guiding decision-making processes in research projects.
- Identify and integrate cutting-edge technologies and methodologies into screening and assay development, anticipating future trends in drug discovery.
- Foster strong cross-functional collaborations with therapeutic area partners to promote innovative ideas and solutions which support organizational objectives.
- Present and explain research findings and strategies clearly and effectively, preparing scientific reports, publications, and presentations for varied audiences.
- Demonstrate scientific excellence through dedication to multiple projects in a fast-paced multi-disciplinary environment.
Qualifications:
- BS with 14+ years of experience or MS with 12+ years of experience or PhD +6 years of experience in Biology, Molecular and Cellular Biology, or another related field.
- Extensive experience in biotherapeutic discovery and screening.
- Demonstrated ability to inspire team members to achieve their best performance, fostering a positive and productive team environment.
- Proficiency in developing and optimizing high-throughput screening assays for biotherapeutic candidates, including cellular and immunoassays.
- Demonstrated ability to lead cross-functional research teams, manage projects, and effectively communicate with stakeholders.
- Experience with state-of-the-art screening technologies and data analysis tools.
Desirable:
- Experience with HTS and enabling automation platforms.
- Experience in managing relationships with Contract Research Organizations (CROs) and external partners.
- Experience with enterprise data capture solutions (GeneData, Dotmatics, Benchling).
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, sex, national origin, age, disability, sexual orientation, gender identity, marital status, status as a protected veteran, or any other legally protected group status.
Principal Scientist I, Cellular/Functional Biology employer: ZipRecruiter
Contact Detail:
ZipRecruiter Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Principal Scientist I, Cellular/Functional Biology
✨Tip Number 1
Network with professionals in the biotherapeutics field, especially those who have experience in cellular and functional biology. Attend relevant conferences or webinars where you can meet potential colleagues from AbbVie and discuss your shared interests.
✨Tip Number 2
Familiarise yourself with the latest advancements in high-throughput screening technologies and methodologies. Being able to discuss these trends during interviews will demonstrate your commitment to staying at the forefront of the industry.
✨Tip Number 3
Prepare to showcase your experience in leading cross-functional teams. Think of specific examples where you successfully collaborated with different departments to achieve a common goal, as this is crucial for the role.
✨Tip Number 4
Practice explaining complex scientific concepts in simple terms. This skill is essential for presenting research findings effectively, so consider rehearsing with friends or colleagues who may not have a scientific background.
We think you need these skills to ace Principal Scientist I, Cellular/Functional Biology
Some tips for your application 🫡
Tailor Your CV: Make sure to customise your CV to highlight relevant experience in biotherapeutic discovery and screening. Emphasise your expertise in developing high-throughput screening assays and any leadership roles you've held in cross-functional teams.
Craft a Compelling Cover Letter: Write a cover letter that clearly outlines your motivation for applying to AbbVie and how your background aligns with their mission. Mention specific projects or experiences that demonstrate your ability to drive innovative ideas in cellular and functional biology.
Highlight Key Skills: In your application, be sure to showcase your proficiency in data analysis tools and state-of-the-art screening technologies. Provide examples of how you've integrated cutting-edge methodologies into your previous work.
Prepare for Potential Questions: Anticipate questions related to your experience with in vitro cell-based assays and your approach to fostering collaboration within teams. Be ready to discuss how you can contribute to AbbVie's goals in drug discovery.
How to prepare for a job interview at ZipRecruiter
✨Showcase Your Technical Expertise
As a Principal Scientist I, you'll need to demonstrate your extensive knowledge in biotherapeutic discovery and screening. Be prepared to discuss specific projects where you've developed high-throughput screening assays or functional assays, highlighting the methodologies and technologies you employed.
✨Emphasise Cross-Functional Collaboration
This role requires strong partnerships with colleagues across various functions. Share examples of how you've successfully collaborated with different teams in the past, focusing on how these collaborations led to innovative solutions or advancements in research.
✨Prepare for Data Analysis Questions
Given the emphasis on analysing complex data sets, be ready to discuss your experience with data analysis tools and how you've used data to guide decision-making in your research projects. Consider bringing examples of data sets you've worked with and the insights you derived from them.
✨Communicate Clearly and Effectively
You'll need to present your findings and strategies to varied audiences. Practice explaining your research in a clear and concise manner, as well as preparing scientific reports and presentations. Tailor your communication style to suit different stakeholders, showcasing your ability to adapt.
