Principal / Senior Scientist Cell Biology
Principal / Senior Scientist Cell Biology

Principal / Senior Scientist Cell Biology

Full-Time 36000 - 60000 £ / year (est.) No home office possible
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At a Glance

  • Tasks: Lead innovative cell biology experiments and mentor junior scientists in a dynamic biotech environment.
  • Company: Join Yellowstone Biosciences, a pioneering biotech spinout from the University of Oxford.
  • Benefits: Enjoy a competitive salary and exciting career development opportunities.
  • Why this job: Make a real impact on cancer treatments with advanced T-cell therapies.
  • Qualifications: PhD in Cell Biology or related field with 5+ years of experience.
  • Other info: Collaborative culture focused on scientific innovation and professional growth.

The predicted salary is between 36000 - 60000 £ per year.

ABOUT THE COMPANY

Yellowstone Biosciences is a biotechnology spinout company located in Oxford, whose goal is to pioneer new cancer treatments using advanced T-cell therapies based on groundbreaking research from the MRC Weatherall Institute of Molecular Medicine at the University of Oxford.

ABOUT THE ROLE

We are seeking a highly motivated and detail-oriented Principal Scientist to join our Cell Biology Team. The successful candidate will help drive experimental strategy, oversee the design and execution of in vitro studies, and play a key role in mentoring and training junior scientists. This position offers an exciting opportunity to shape the scientific direction of a growing company and to contribute directly to its research and development strategy.

RESPONSIBILITIES

  • Lead the planning, execution, and interpretation of cell biology experiments to support discovery and preclinical programs.
  • Supervise and train research associates and scientists, fostering a culture of scientific rigor, collaboration, and professional growth.
  • Develop, implement, and optimize assays including flow cytometry, ELISA, Western blotting, and advanced cell culture models.
  • Guide molecular biology studies (e.g., gene expression analysis, cloning, transfection, CRISPR) to support mechanistic investigations.
  • Ensure high-quality data generation, documentation, and communication across multidisciplinary teams.
  • Collaborate with project leads to design experimental plans, review data, and integrate findings into project decisions.
  • Lead presentations at internal meetings and contribute to scientific reports and regulatory documentation.
  • Contribute to the shaping of the company’s scientific strategy and research roadmap.

QUALIFICATIONS

  • PhD (or equivalent experience) in Cell Biology, Molecular Biology, Immunology, or related scientific field.
  • Proven experience (typically 5+ years post-PhD) in cell biology or related research within a biotech/biopharma settings.

REQUIRED SKILLS

  • Strong technical background in cell culture, flow cytometry, ELISA, Western blotting, and molecular biology techniques.
  • Familiarity with a range of cell and molecular biology techniques including T cell assays, killing assays, cytokine assays, designing and executing recombinant DNA sub-cloning strategies, making lentiviral supernatants, lentiviral transduction, complex co-culture or 3D culture assays.
  • Experience leading projects, overseeing the experimental strategy and co-ordinating the work of other team members.
  • Excellent communication and organizational skills, with the ability to present data clearly and influence across functional teams.
  • Demonstrated ability to work proactively in a dynamic, fast-evolving start-up environment.

PREFERRED SKILLS

  • Direct hands-on laboratory experience in testing and developing of biologics including the assessment of the biological impact of their engagement with therapeutic targets.
  • Ability to independently lead programmes to advance the company’s goals, review competing priorities and recommend strategies to advance the programme.
  • Inclusive, collaborative, and thrives in a team environment with a flexible approach to working.
  • Demonstrable problem-solving ability, creative thinking and be pro-active in driving the project forwards.
  • Experience in the design and oversight of in vivo experiments.
  • Passionate about scientific innovation and advancing new therapeutic approaches.

PAY RANGE AND COMPENSATION PACKAGE

Competitive salary and career development opportunities. If you’re excited to grow your skills and make a real impact in cutting-edge cell biology research, we’d love to hear from you.

Principal / Senior Scientist Cell Biology employer: Yellowstone Biosciences

Yellowstone Biosciences is an exceptional employer located in the vibrant city of Oxford, offering a dynamic work culture that fosters innovation and collaboration. As a Principal Scientist, you will not only lead groundbreaking research in T-cell therapies but also have the opportunity to mentor junior scientists, ensuring your professional growth while contributing to meaningful advancements in cancer treatment. With competitive salaries and a commitment to career development, joining our team means being part of a pioneering effort in biotechnology that truly makes a difference.
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Contact Detail:

Yellowstone Biosciences Recruiting Team

StudySmarter Expert Advice 🤫

We think this is how you could land Principal / Senior Scientist Cell Biology

✨Network Like a Pro

Get out there and connect with folks in the industry! Attend conferences, seminars, or even local meetups. You never know who might have the inside scoop on job openings or can put in a good word for you.

✨Show Off Your Skills

When you get the chance to chat with potential employers, make sure to highlight your hands-on experience with techniques like flow cytometry and ELISA. Share specific examples of how you've led projects or mentored others to showcase your leadership skills.

✨Tailor Your Approach

Before any interview, do your homework on the company and its research focus. Tailor your responses to show how your background in cell biology aligns with their goals. This will help you stand out as a candidate who truly understands their mission.

✨Apply Through Our Website

Don’t forget to apply directly through our website! It’s the best way to ensure your application gets seen by the right people. Plus, it shows you're genuinely interested in being part of our team at Yellowstone Biosciences.

We think you need these skills to ace Principal / Senior Scientist Cell Biology

Cell Culture
Flow Cytometry
ELISA
Western Blotting
Molecular Biology Techniques
Gene Expression Analysis
Cloning
Transfection
CRISPR
Project Leadership
Communication Skills
Organisational Skills
Data Presentation
Problem-Solving
Collaboration

Some tips for your application 🫡

Tailor Your CV: Make sure your CV reflects the specific skills and experiences mentioned in the job description. Highlight your expertise in cell biology techniques and any relevant projects you've led. We want to see how you can contribute to our team!

Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you're passionate about cancer research and how your background aligns with our mission at Yellowstone Biosciences. Keep it engaging and personal, so we get a sense of who you are.

Showcase Your Leadership Skills: Since this role involves mentoring and leading projects, be sure to highlight any experience you have in supervising teams or training others. We love candidates who can inspire and guide their colleagues while driving scientific innovation.

Apply Through Our Website: We encourage you to submit your application through our website for the best chance of being noticed. It’s straightforward and ensures your application goes directly to us. We can’t wait to see what you bring to the table!

How to prepare for a job interview at Yellowstone Biosciences

✨Know Your Science

Make sure you brush up on the latest advancements in cell biology, especially those related to T-cell therapies. Be prepared to discuss your previous research and how it aligns with the company's goals. This shows that you're not just knowledgeable but also genuinely interested in their work.

✨Showcase Your Leadership Skills

Since this role involves mentoring junior scientists, be ready to share examples of how you've successfully led teams or projects in the past. Highlight your ability to foster collaboration and professional growth, as this is key for the position.

✨Prepare for Technical Questions

Expect to dive deep into technical discussions about assays like flow cytometry and ELISA. Brush up on your methodologies and be ready to explain your approach to experimental design and data interpretation. This will demonstrate your strong technical background.

✨Communicate Clearly

Practice presenting complex data in a clear and concise manner. You might be asked to present findings or discuss your research during the interview, so being able to communicate effectively across multidisciplinary teams is crucial.

Principal / Senior Scientist Cell Biology
Yellowstone Biosciences

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