At a Glance
- Tasks: Design and analyse cell-based assays for innovative cancer therapies.
- Company: Join Yellowstone Biosciences, a pioneering biotech in Oxford.
- Benefits: Collaborative environment with opportunities for impactful research.
- Other info: Dynamic team atmosphere with continuous learning and growth.
- Why this job: Make a real difference in cancer treatment and patient lives.
- Qualifications: BSc, MSc, or PhD in relevant fields with hands-on lab experience.
The predicted salary is between 35000 - 45000 £ per year.
We're looking for a talented and motivated Scientist to join our Cell Biology team at Yellowstone Biosciences in Oxford. This is an exciting opportunity to contribute directly to the discovery and characterisation of novel T cell engaging cancer therapies within a fast-paced and collaborative biotech environment. You'll play a key role in designing, executing, and analysing cellular assays that support our drug discovery programmes and help drive critical scientific decisions.
ABOUT THE COMPANY
Yellowstone Biosciences is a biotechnology spinout based in Oxford, focused on pioneering next-generation cancer treatments using advanced T cell engaging therapies. Our work builds on leading research from the MRC Weatherall Institute of Molecular Medicine at the University of Oxford, translating cutting-edge science into innovative therapeutics with real clinical impact. As we continue to grow, we're seeking passionate scientists who are eager to contribute to breakthrough discoveries and make a meaningful impact on patients' lives.
ABOUT THE ROLE
As a Scientist within our Cell Biology team, you will design and perform a range of in vitro assays to evaluate novel therapeutic candidates. Working closely with colleagues across biology and protein science you'll generate high-quality experimental data and contribute to projects from early-stage discovery through to decision-making. This role is ideal for a laboratory-based scientist who enjoys hands-on research, solving complex scientific problems, and working within a multidisciplinary team developing next-generation cancer therapeutics.
What you'll do:
- Design, perform, and analyse cell-based assays to evaluate therapeutic candidates
- Culture and maintain mammalian cell lines and primary immune cells
- Conduct flow cytometry experiments, including staining, assay optimisation, data acquisition, and analysis
- Perform ELISA and other immunoassays to quantify cytokines, biomarkers, and protein expression
- Support assay development and optimisation
- Maintain accurate experimental records using electronic laboratory notebooks
- Analyse, interpret, and present experimental data to project teams
- Collaborate with colleagues across multiple scientific disciplines to advance research programmes
- Contribute to laboratory organisation, equipment maintenance, and continuous improvement initiatives
- Ensure all laboratory activities are conducted in accordance with company safety and quality standards
Who we're looking for:
Essential
- BSc, MSc, or PhD (plus 2+ years post-qualification research experience) in Cell Biology, Immunology, Biomedical Sciences, Biotechnology, or a related discipline
- Hands-on experience with mammalian cell culture techniques
- Practical experience performing ELISA assays
- Experience with flow cytometry, including sample preparation, staining, instrument operation, and data analysis
- Strong experimental design, troubleshooting, and problem-solving skills
- Excellent organisational skills and attention to detail
- Strong written and verbal communication skills
- Ability to work independently while contributing effectively within a multidisciplinary team
Desirable
- Experience working with primary human immune cells, including PBMCs and T cells
- Knowledge of T cell biology, immune activation, and cancer immunology
- Experience with T cell functional assays, including cytokine release, proliferation, or cytotoxicity assays
- Familiarity with T cell engaging therapies, bispecific antibodies, CAR-T, or TCR-T approaches
- Experience using FlowJo or similar flow cytometry analysis software
- Experience analysing scientific data using GraphPad Prism or equivalent tools
- Understanding of assay development and validation principles
How to apply:
Please submit your CV together with a brief cover letter outlining your interest in the role and how your experience aligns with the requirements. Applications will be reviewed on a rolling basis, so early applications are encouraged.
StudySmarter Expert Advice🤫
We think this is how you could land Cell biology scientist in Oxford
✨Get Involved in Local Research Communities
Tap into local biotechnology meetups and research forums. These are great places to mingle with industry professionals, share your passion, and even discover unadvertised job openings. It's all about getting your face known in the field!
✨Leverage University Alumni Networks
If you're a recent grad, don’t underestimate the power of your university’s alumni network! Reach out to alumni working in biotechnology to gather tips about job openings at companies like Yellowstone Biosciences. You'd be surprised how willing people are to help out a fellow grad!
✨Show Off Your Projects
Curate a portfolio showcasing any research projects or internships you've completed in biotechnology. This tangible evidence of your skills can really impress employers when you chat with them at networking events or interviews. It's about making that killer first impression!
✨Stay Up-to-Date with Industry Trends
Biotech is a fast-paced field, so keeping yourself updated with the latest advancements is crucial. Attend industry conferences, webinars, or workshops to broaden your knowledge and meet potential employers. Plus, it’ll give you fantastic talking points for your interviews at places like Yellowstone Biosciences!
We think you need these skills to ace Cell biology scientist in Oxford
Some tips for your application 🫡
Show Off Your Lab Skills:In the biotechnology field, it's super important to highlight your lab experience in your CV. Be sure to mention specific techniques or instruments you've mastered (think PCR, gel electrophoresis, etc.) and any relevant projects you've worked on. This will show Yellowstone Biosciences that you have the hands-on skills they need.
Tailor Your Technical Skills:Make sure to emphasise your technical skills, especially those relevant to the biotechnology sector. Include any software tools or programming languages you've used, like R or Python for data analysis, which could be key for this role at Yellowstone Biosciences.
Craft a Compelling Cover Letter:Since this is a full-time role, your cover letter should reflect not only your passion for biotechnology but also your long-term career ambitions. Share why you're excited about the work that Yellowstone Biosciences does and how you envision contributing to their goals. This shows that you’re not just looking for any job, but you're genuinely invested in this opportunity.
Include Your Papers and Projects:If you've published any papers or contributed to significant projects, mention them! These documents can boost your application and provide tangible evidence of your expertise in the biotechnology field. Don’t forget to link to any relevant publications or project summaries—this can set you apart from other candidates.
How to prepare for a job interview at Yellowstone Biosciences
✨Brush Up on Lab Techniques
Since you're eyeing a full-time gig in biotechnology, make sure you're well-versed in the lab techniques relevant to the role. Be ready to talk about PCR, CRISPR, or any specific methods mentioned in the job description at Yellowstone Biosciences. You might even be asked to demonstrate your understanding of these processes.
✨Know Your Bioinformatics Tools
Get comfortable with bioinformatics tools that are commonly used in the industry, like BLAST or Bioconductor. These are key in biotechnology, and having hands-on experience or at least familiarity can set you apart. Prepare to discuss any relevant projects you've worked on, especially if they involved data analysis or genomic research.
✨Show Your Teamwork Skills
Biotech often involves collaboration across multiple disciplines. Be ready to share stories that highlight your teamwork and communication skills, especially in research projects. Think about working with different teams at university or any internships – this is where you can show how well you fit into Yellowstone Biosciences's culture.
✨Research Recent Biotech Innovations
Stay updated on the latest trends and breakthroughs in biotechnology. Knowing what's happening in the field can help you engage in more meaningful discussions during your interview. Bring up recent articles or advancements that excite you, especially those related to the work being done at Yellowstone Biosciences. This shows your passion for the industry!
