At a Glance
- Tasks: Design and analyse cell-based assays for innovative cancer therapies.
- Company: Join Yellowstone Biosciences, a pioneering biotech in Oxford.
- Benefits: Collaborative environment with opportunities for impactful research.
- Other info: Dynamic team atmosphere with continuous learning and growth.
- Why this job: Make a real difference in cancer treatment and patient lives.
- Qualifications: BSc, MSc, or PhD in relevant fields with hands-on lab experience.
The predicted salary is between 35000 - 45000 £ per year.
🔬 Cell biology scientist We're looking for a talented and motivated Scientist to join our Cell Biology team at Yellowstone Biosciences in Oxford.
This is an exciting opportunity to contribute directly to the discovery and characterisation of novel T cell engaging cancer therapies within a fast-paced and collaborative biotech environment.
You'll play a key role in designing, executing, and analysing cellular assays that support our drug discovery programmes and help drive critical scientific decisions.
ABOUT THE COMPANY Yellowstone Biosciences is a biotechnology spinout based in Oxford, focused on pioneering next-generation cancer treatments using advanced T cell engaging therapies.
Our work builds on leading research from the MRC Weatherall Institute of Molecular Medicine at the University of Oxford, translating cutting-edge science into innovative therapeutics with real clinical impact.
As we continue to grow, we're seeking passionate scientists who are eager to contribute to breakthrough discoveries and make a meaningful impact on patients' lives.
ABOUT THE ROLE As a Scientist within our Cell Biology team, you will design and perform a range of in vitro assays to evaluate novel therapeutic candidates.
Working closely with colleagues across biology and protein science you'll generate high-quality experimental data and contribute to projects from early-stage discovery through to decision-making.
This role is ideal for a laboratory-based scientist who enjoys hands-on research, solving complex scientific problems, and working within a multidisciplinary team developing next-generation cancer therapeutics. 🔬 What you'll do
- Design, perform, and analyse cell-based assays to evaluate therapeutic candidates
- Culture and maintain mammalian cell lines and primary immune cells
- Conduct flow cytometry experiments, including staining, assay optimisation, data acquisition, and analysis
- Perform ELISA and other immunoassays to quantify cytokines, biomarkers, and protein expression
- Support assay development and optimisation
- Maintain accurate experimental records using electronic laboratory notebooks
- Analyse, interpret, and present experimental data to project teams
- Collaborate with colleagues across multiple scientific disciplines to advance research programmes
- Contribute to laboratory organisation, equipment maintenance, and continuous improvement initiatives
- Ensure all laboratory activities are conducted in accordance with company safety and quality standards 🎓 Who we're looking for Essential
- BSc, MSc, or Ph D (plus 2+ years post-qualification research experience) in Cell Biology, Immunology, Biomedical Sciences, Biotechnology, or a related discipline
- Hands-on experience with mammalian cell culture techniques
- Practical experience performing ELISA assays
- Experience with flow cytometry, including sample preparation, staining, instrument operation, and data analysis
- Strong experimental design, troubleshooting, and problem-solving skills
- Excellent organisational skills and attention to detail
- Strong written and verbal communication skills
- Ability to work independently while contributing effectively within a multidisciplinary team Desirable
- Experience working with primary human immune cells, including PBMCs and T cells
- Knowledge of T cell biology, immune activation, and cancer immunology
- Experience with T cell functional assays, including cytokine release, proliferation, or cytotoxicity assays
- Familiarity with T cell engaging therapies, bispecific antibodies, CAR-T, or TCR-T approaches
- Experience using Flow Jo or similar flow cytometry analysis software
- Experience analysing scientific data using Graph Pad Prism or equivalent tools
- Understanding of assay development and validation principles 📩 How to apply Please submit your CV together with a brief cover letter outlining your interest in the role and how your experience aligns with the requirements.
Applications will be reviewed on a rolling basis, so early applications are encouraged.
Cell biology scientist employer: Yellowstone Biosciences
At Yellowstone Biosciences, we pride ourselves on being an exceptional employer, offering a dynamic and collaborative work environment in the heart of Oxford. Our commitment to employee growth is evident through our focus on pioneering cancer therapies, providing scientists with the opportunity to engage in meaningful research that directly impacts patient lives. With access to cutting-edge resources and a culture that fosters innovation and teamwork, joining our Cell Biology team means becoming part of a mission-driven organisation dedicated to making a real difference in the field of biotechnology.
