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For Companies At a Glance
- Tasks: Lead innovative drug development strategies and collaborate with cross-functional teams.
- Company: Join GSK, a leader in pharmaceutical innovation and research.
- Benefits: Competitive salary, bonuses, health care, and generous leave policies.
- Other info: Flexible working options available across the UK and Europe.
- Why this job: Make a real impact on patient access to novel therapies and drive scientific excellence.
- Qualifications: PhD or MD with extensive experience in clinical pharmacology and drug development.
The Department of Clinical Pharmacology Modelling & Simulation Respiratory and Inflammation (CPMS R&I) at GSK is recruiting a director-level Clinical Pharmacologist. The role is based in the UK or US, with remote working or placement at other European GSK sites possible for the right candidate.
Job Purpose
The Director, Clinical Pharmacology sits within the newly established Clinical Pharmacology and Quantitative Medicine (CPQM) organisation and aims to be a centre of excellence in Model‑Informed Drug Development (MIDD) by integrating clinical pharmacology, digital medicine, translational imaging and mechanistic/systems modelling. You will lead the end‑to‑end application of MIDD across the drug development lifecycle—from first‑in‑human studies through filing and lifecycle management—and provide clinical pharmacology strategy and evidence-generation input.
Main Responsibilities
- Design & Execute Model Informed and Clinical Pharmacology strategies: Develop and implement robust MIDD & ClinPharm evidence strategies to de‑risk and accelerate RIIRU programs, with a focus on faster development, optimal dosing and stronger regulatory positioning across respiratory, inflammation, neurodegeneration and emerging areas.
- Ensure robust ways of working and regulatory‑ready evidence: Draft and review clinical pharmacology regulatory content to support timely approvals and optimal labelling; maintain up‑to‑date knowledge of FDA, EMA, CDE, PMDA and ICH expectations and embed regulatory considerations into study design and MIDD strategies.
- Build cross‑functional partnerships: Work closely with CPQM peers (digital medicine, translational imaging, MIDD specialists, mechanistic/systems modelling) and cross‑functional partners (biology, data science, computational biology, clinical, etc.). Maintain strong networks and share best practices in the CPMS community of practice; collaborate with key functions such as AI/ML, biomarkers, biostatistics, clinical operations, data science, computational biology and RWE.
- External engagement & scientific leadership: Raise GSK’s profile in MIDD, clinical pharmacology, QSP and AI/ML integration through publications, conference presentations and active participation in scientific and regulatory fora.
Basic Qualifications
- PhD in life sciences or related discipline, MD or PharmD with experience in clinical pharmacology, modelling and simulation in pharmaceutical research and development.
- Significant experience in clinical pharmacology, modelling/simulation and drug development to solve practical problems in the pharmaceutical industry.
- Experience in pharmacometrics and their application to clinical questions in drug development.
Preferred Qualifications
- Additional experience in respiratory and immunology would be beneficial.
- Demonstrated collaboration in a multi-discipline team, using effective communication and taking personal accountability for timely delivery of results.
- Evidenced experience making sound judgement in complex situations and adapting to changing business needs by prioritizing multiple tasks.
- Experience working with senior stakeholders in a cross‑functional environment.
- Track record of implementation of MIDD approaches to accelerate patient access to novel therapies and to expand therapeutic indications of marketed drugs.
- Drive and learning agility to build knowledge on a drug‑disease system, symptom progression, standard of care and trial design.
Salary and Benefits
For US candidates in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary ranges from $188,100 to $313,500. The position offers an annual bonus, eligibility to participate in a share‑based long‑term incentive program and benefits including health care, retirement, paid holidays, vacation and paid caregiver/parental and medical leave.
Director Clinical Pharmacology in London employer: WISE Campaign
Contact Detail:
WISE Campaign Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Director Clinical Pharmacology in London
✨Tip Number 1
Network like a pro! Reach out to professionals in the clinical pharmacology field on LinkedIn or at industry events. We can’t stress enough how important it is to build relationships; you never know who might have the inside scoop on job openings.
✨Tip Number 2
Prepare for interviews by brushing up on your knowledge of Model-Informed Drug Development (MIDD) and current trends in clinical pharmacology. We recommend practising common interview questions with a friend or mentor to boost your confidence.
✨Tip Number 3
Showcase your expertise! Create a portfolio that highlights your experience in pharmacometrics and drug development. We suggest including case studies or examples of your work to impress potential employers.
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets noticed. Plus, we often have exclusive roles listed there that you won’t find anywhere else.
We think you need these skills to ace Director Clinical Pharmacology in London
Some tips for your application 🫡
Tailor Your Application: Make sure to customise your CV and cover letter to highlight your experience in clinical pharmacology and modelling. We want to see how your skills align with the role, so don’t hold back on showcasing relevant projects or achievements!
Showcase Your Collaboration Skills: Since this role involves building cross-functional partnerships, it’s essential to demonstrate your teamwork abilities. Share examples of how you've successfully collaborated with different teams or stakeholders in your previous roles.
Highlight Your Regulatory Knowledge: Given the importance of regulatory considerations in this position, make sure to mention your familiarity with FDA, EMA, and other regulatory bodies. We’re looking for candidates who can navigate these waters smoothly, so any relevant experience is a plus!
Apply Through Our Website: We encourage you to apply directly through our website for a seamless application process. It’s the best way for us to receive your application and ensure it gets the attention it deserves. Don’t miss out on this opportunity!
How to prepare for a job interview at WISE Campaign
✨Know Your MIDD Inside Out
Make sure you have a solid understanding of Model-Informed Drug Development (MIDD) and how it applies to the role. Brush up on recent advancements in clinical pharmacology, especially in respiratory and inflammation areas. Being able to discuss specific examples of how you've applied MIDD strategies in your past work will really impress.
✨Regulatory Knowledge is Key
Familiarise yourself with the latest FDA, EMA, and ICH guidelines. Be prepared to discuss how you’ve integrated regulatory considerations into study designs before. Showing that you can navigate these complexities will demonstrate your readiness for the role.
✨Showcase Your Collaborative Spirit
This role requires strong cross-functional partnerships, so be ready to share examples of how you've successfully collaborated with diverse teams. Highlight your communication skills and how you’ve taken accountability for delivering results in a multi-disciplinary environment.
✨Engage with Scientific Leadership
Prepare to talk about your contributions to the field, whether through publications or conference presentations. Discuss how you’ve raised your previous organisation's profile in clinical pharmacology and MIDD. This shows not only your expertise but also your passion for the field.