At a Glance
- Tasks: Lead scientific assessments and collaborate with experts in clinical outcomes research.
- Company: Join Wiley, a forward-thinking company dedicated to impactful science and innovation.
- Benefits: Competitive salary, inclusive culture, and opportunities for professional growth.
- Other info: Engage with leading medical societies and contribute to groundbreaking research.
- Why this job: Make a real difference in clinical outcomes while working with top professionals in the field.
- Qualifications: Postgraduate degree and 5+ years in clinical outcome assessments required.
The predicted salary is between 53000 - 75867 € per year.
We believe in bold ideas, diverse perspectives, and the drive to transform knowledge into impact. Here, your curiosity fuels progress, your voice shapes innovation, and your ambition helps redefine what’s possible within science and learning. We are a culture that obsesses over impact, challenges, and drives what’s next to power infinite possibilities for our customers, colleagues and society at large.
About The Role
We are looking for a Principal Scientist to be the senior scientific voice across Wiley's Clinical Outcome Assessment (COA) work, part of our AI and Data Analytics organization. The role exists to make sure that the science underpinning every instrument we work with is sound, current, and well‑represented, and that decisions across our business reflect the views of clinical authors and instrument developers. The role works closely with the medical societies and academic authors who originated these instruments, supports their continued scientific development, and represents Wiley credibly in the clinical outcomes community. It is an opportunity to do real scientific work alongside commercial, product, partnership, and publishing colleagues, and reports to the Senior Director, Clinical Outcome Assessments.
Job Responsibilities
- Provide expert scientific assessment of instruments across the portfolio, evaluating psychometric properties, validation evidence, and regulatory precedent in line with current measurement science.
- Work closely with the medical societies, instrument authors, and academic groups behind the instruments in our portfolio, supporting their scientific work and acting as a senior point of contact for scientific questions.
- Support the continued scientific development of instruments alongside their authors and Scientific Affairs colleagues, including evidence updates, validation work, and considered translation and adaptation programmes.
- Provide scientific guidance to colleagues across the business so that customer conversations, product builds, and partnership decisions all reflect sound clinical measurement principles.
- Represent Wiley as an active and credible participant in the clinical outcomes community, including at ISOQOL, ISPOR, CPATH, and other professional forums.
- Provide scientific input to clinical platform product development, ensuring the platforms are built on sound clinical foundations and respect the integrity of the underlying instruments.
Required Qualifications
- Postgraduate degree (MSc, PhD, or equivalent) in clinical outcomes research, psychometrics, health economics and outcomes research (HEOR), epidemiology, clinical psychology, or a closely related discipline.
- Strong academic background combined with substantial practical experience in clinical measurement science is also acceptable.
- 5+ years working with Clinical Outcome Assessments in a scientific, regulatory, or commercial context, including roles in pharmaceutical clinical development, CRO scientific affairs, health outcomes consultancy, academic research in psychometrics or patient‑reported outcomes, or regulatory science.
- Demonstrated ability to evaluate the psychometric properties and clinical utility of measurement instruments.
- Familiarity with the regulatory landscape for COAs, including FDA Patient‑Focused Drug Development guidance, EMA qualification, and ICH standards.
- Strong literature review and evidence synthesis skills.
- Familiarity with psychometric validation methodologies (classical test theory, item response theory, Rasch analysis).
- Ability to communicate complex scientific and psychometric concepts to both technical and non‑technical audiences, with credibility among clinical and academic peers.
Preferred Qualifications
- PhD in psychometrics, HEOR, or clinical outcomes research.
- Published research in COA‑related fields.
- Experience working across multiple therapeutic areas.
- Track record of contributing to instrument development, validation, or regulatory submission, ideally in collaboration with academic or society partners.
- Experience with systematic evidence review or meta‑analysis.
- Familiarity with CDISC standards for COA data.
- Active engagement with ISOQOL, ISPOR, CPATH, or equivalent professional communities.
- Familiarity with electronic COA implementation and the impact of mode of administration on measurement properties.
- Knowledge of AI‑assisted evidence synthesis approaches.
Salary Range: 53,000 GBP to 75,867 GBP
Principal Scientist, Clinical Outcomes employer: Wiley
Wiley is an exceptional employer that champions bold ideas and diverse perspectives, fostering a culture where your curiosity drives progress and your contributions shape innovation. Located in the vibrant city of Oxford, we offer a collaborative work environment that prioritises scientific integrity and employee growth, providing opportunities to engage with leading medical societies and contribute to impactful clinical outcomes research. With a commitment to inclusivity and professional development, Wiley empowers its employees to redefine possibilities within science and learning.
StudySmarter Expert Advice🤫
We think this is how you could land Principal Scientist, Clinical Outcomes
✨Tip Number 1
Network like a pro! Reach out to professionals in the clinical outcomes community, attend relevant conferences, and engage with them on social media. Building relationships can open doors that a CV just can't.
✨Tip Number 2
Show off your expertise! Prepare to discuss your past projects and how they relate to the role. Be ready to explain complex concepts in simple terms – it shows you really know your stuff and can communicate effectively.
✨Tip Number 3
Be proactive! Don’t wait for job openings to apply. If you see a company you love, reach out directly. Express your interest and share how your skills align with their goals. We love seeing enthusiasm!
✨Tip Number 4
Utilise our website! Apply through StudySmarter to streamline your application process. It’s a great way to ensure your application gets noticed and shows you’re serious about joining our team.
We think you need these skills to ace Principal Scientist, Clinical Outcomes
Some tips for your application 🫡
Show Your Passion for Science:When writing your application, let your enthusiasm for clinical outcomes and measurement science shine through. We want to see how your curiosity fuels your work and how you can contribute to our mission of transforming knowledge into impact.
Tailor Your Experience:Make sure to highlight your relevant experience in clinical outcome assessments and psychometrics. We’re looking for specific examples that demonstrate your ability to evaluate psychometric properties and your familiarity with regulatory landscapes. Tailoring your application will help us see how you fit into our team.
Be Clear and Concise:While we appreciate detail, clarity is key! Use straightforward language to communicate your qualifications and experiences. Remember, we want to understand your expertise without getting lost in jargon or overly complex explanations.
Apply Through Our Website:Don’t forget to submit your application through our website! It’s the best way for us to receive your details and ensures you’re considered for the role. Plus, it gives you a chance to explore more about our culture and values while you’re at it.
How to prepare for a job interview at Wiley
✨Know Your Science
Make sure you brush up on the latest developments in clinical outcomes research and psychometrics. Be prepared to discuss specific instruments you've worked with, their psychometric properties, and any validation evidence you've encountered. This will show your depth of knowledge and passion for the field.
✨Engage with the Community
Familiarise yourself with key organisations like ISOQOL and ISPOR. Mention any relevant conferences or forums you've attended, and be ready to discuss how these experiences have shaped your understanding of clinical outcome assessments. This demonstrates your active engagement and credibility in the community.
✨Communicate Clearly
Practice explaining complex scientific concepts in simple terms. You might be asked to present your ideas to both technical and non-technical audiences, so being able to adapt your communication style is crucial. Think of examples where you've successfully done this in the past.
✨Showcase Your Collaboration Skills
Highlight your experience working with medical societies, academic authors, and cross-functional teams. Be ready to share specific examples of how you've supported scientific development or contributed to instrument validation. This will illustrate your ability to work collaboratively and drive impactful results.
