At a Glance
- Tasks: Lead scientific assessments and collaborate with experts in clinical outcomes research.
- Company: Join Wiley, a forward-thinking company dedicated to impactful science and innovation.
- Benefits: Competitive salary, inclusive culture, and opportunities for professional growth.
- Other info: Engage with leading medical societies and contribute to groundbreaking research.
- Why this job: Make a real difference in clinical outcomes while working with top professionals in the field.
- Qualifications: Postgraduate degree and 5+ years in clinical outcome assessments required.
The predicted salary is between 53000 - 75867 € per year.
We believe in bold ideas, diverse perspectives, and the drive to transform knowledge into impact. Here, your curiosity fuels progress, your voice shapes innovation, and your ambition helps redefine what’s possible within science and learning. We are a culture that obsesses over impact, challenges, and drives what’s next to power infinite possibilities for our customers, colleagues and society at large.
About The Role
We are looking for a Principal Scientist to be the senior scientific voice across Wiley's Clinical Outcome Assessment (COA) work, part of our AI and Data Analytics organization. The role exists to make sure that the science underpinning every instrument we work with is sound, current, and well‑represented, and that decisions across our business reflect the views of clinical authors and instrument developers. The role works closely with the medical societies and academic authors who originated these instruments, supports their continued scientific development, and represents Wiley credibly in the clinical outcomes community. It is an opportunity to do real scientific work alongside commercial, product, partnership, and publishing colleagues, and reports to the Senior Director, Clinical Outcome Assessments.
Job Responsibilities
- Provide expert scientific assessment of instruments across the portfolio, evaluating psychometric properties, validation evidence, and regulatory precedent in line with current measurement science.
- Work closely with the medical societies, instrument authors, and academic groups behind the instruments in our portfolio, supporting their scientific work and acting as a senior point of contact for scientific questions.
- Support the continued scientific development of instruments alongside their authors and Scientific Affairs colleagues, including evidence updates, validation work, and considered translation and adaptation programmes.
- Provide scientific guidance to colleagues across the business so that customer conversations, product builds, and partnership decisions all reflect sound clinical measurement principles.
- Represent Wiley as an active and credible participant in the clinical outcomes community, including at ISOQOL, ISPOR, CPATH, and other professional forums.
- Provide scientific input to clinical platform product development, ensuring the platforms are built on sound clinical foundations and respect the integrity of the underlying instruments.
Required Qualifications
- Postgraduate degree (MSc, PhD, or equivalent) in clinical outcomes research, psychometrics, health economics and outcomes research (HEOR), epidemiology, clinical psychology, or a closely related discipline.
- Strong academic background combined with substantial practical experience in clinical measurement science is also acceptable.
- 5+ years working with Clinical Outcome Assessments in a scientific, regulatory, or commercial context, including roles in pharmaceutical clinical development, CRO scientific affairs, health outcomes consultancy, academic research in psychometrics or patient‑reported outcomes, or regulatory science.
- Demonstrated ability to evaluate the psychometric properties and clinical utility of measurement instruments.
- Familiarity with the regulatory landscape for COAs, including FDA Patient‑Focused Drug Development guidance, EMA qualification, and ICH standards.
- Strong literature review and evidence synthesis skills.
- Familiarity with psychometric validation methodologies (classical test theory, item response theory, Rasch analysis).
- Ability to communicate complex scientific and psychometric concepts to both technical and non‑technical audiences, with credibility among clinical and academic peers.
Preferred Qualifications
- PhD in psychometrics, HEOR, or clinical outcomes research.
- Published research in COA‑related fields.
- Experience working across multiple therapeutic areas.
- Track record of contributing to instrument development, validation, or regulatory submission, ideally in collaboration with academic or society partners.
- Experience with systematic evidence review or meta‑analysis.
- Familiarity with CDISC standards for COA data.
- Active engagement with ISOQOL, ISPOR, CPATH, or equivalent professional communities.
- Familiarity with electronic COA implementation and the impact of mode of administration on measurement properties.
- Knowledge of AI‑assisted evidence synthesis approaches.
Salary Range 53,000 GBP to 75,867 GBP
Principal Scientist, Clinical Outcomes in Oxford employer: Wiley
Wiley is an exceptional employer that champions bold ideas and diverse perspectives, fostering a culture where your scientific curiosity and ambition can truly make an impact. Located in the vibrant city of Oxford, we offer a collaborative work environment that encourages professional growth through meaningful contributions to clinical outcomes research, while also providing opportunities to engage with leading medical societies and academic authors. With a commitment to innovation and inclusivity, Wiley empowers its employees to shape the future of science and learning.
StudySmarter Expert Advice🤫
We think this is how you could land Principal Scientist, Clinical Outcomes in Oxford
✨Tip Number 1
Network like a pro! Reach out to professionals in the clinical outcomes community, attend relevant conferences, and engage with them on social media. Building relationships can open doors that a CV just can't.
✨Tip Number 2
Show off your expertise! Prepare to discuss your past projects and how they relate to the role. Be ready to share insights on psychometric properties and validation evidence – it’ll show you know your stuff.
✨Tip Number 3
Practice makes perfect! Conduct mock interviews with friends or mentors who understand the field. This will help you articulate your thoughts clearly and confidently when discussing complex scientific concepts.
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets noticed. Plus, it shows you’re genuinely interested in being part of our innovative team at Wiley.
We think you need these skills to ace Principal Scientist, Clinical Outcomes in Oxford
Some tips for your application 🫡
Show Your Passion for Science:When writing your application, let your enthusiasm for clinical outcomes and measurement science shine through. We want to see how your curiosity fuels your work and how you can contribute to our mission of transforming knowledge into impact.
Tailor Your Experience:Make sure to highlight your relevant experience in clinical outcome assessments and psychometrics. We’re looking for specific examples that demonstrate your ability to evaluate psychometric properties and your familiarity with regulatory landscapes. Tailoring your application will help us see how you fit into our team.
Communicate Clearly:We value the ability to communicate complex concepts simply. In your written application, aim for clarity and conciseness. Use straightforward language to explain your scientific background and how it relates to the role, ensuring both technical and non-technical audiences can understand your expertise.
Apply Through Our Website:Don’t forget to submit your application through our website! It’s the best way for us to receive your details and ensures you’re considered for the role. Plus, it shows you’re keen on joining our community at Wiley.
How to prepare for a job interview at Wiley
✨Know Your Science
Make sure you brush up on the latest developments in clinical outcomes research and psychometrics. Be prepared to discuss specific instruments you've worked with, their psychometric properties, and any relevant regulatory guidelines. This will show your depth of knowledge and passion for the field.
✨Engage with the Community
Familiarise yourself with key organisations like ISOQOL and ISPOR. Mention any past engagements or contributions you've made to these communities during the interview. This demonstrates your commitment to staying connected and active in the clinical outcomes space.
✨Prepare for Technical Questions
Expect questions that dive deep into psychometric validation methodologies and evidence synthesis. Practise explaining complex concepts in simple terms, as you'll need to communicate effectively with both technical and non-technical audiences.
✨Showcase Your Collaborative Spirit
Highlight your experience working with medical societies, academic authors, and cross-functional teams. Share examples of how you've supported scientific development and contributed to successful projects, as collaboration is key in this role.
