Principal Biostatistician | Global CRO | FSP | Home Based | UK | Europe | Permanent | Our client, a leading global CRO, is seeking an experienced Principal Biostatistician to join a dedicated FSP team, supporting real-world evidence, pharmacoepidemiology, outcomes research, and non-interventional study programmes. This is an excellent opportunity for a senior statistician with strong real-world data experience to work across impactful studies using electronic health records, claims data, registries, and other real-world data sources. You will provide statistical leadership across non-interventional studies, safety and comparative effectiveness research, and pharmacoepidemiology projects, partnering closely with clients, internal teams, and cross-functional stakeholders. This position can be home-based across Europe, including UK, Bulgaria, Hungary, Poland, Romania What you will be doing: Lead statistical activities across real-world evidence, pharmacoepidemiology, and non-interventional studies Contribute to and review protocols, statistical analysis plans, and study reports Scope, design, and deliver analyses using real-world data sources including EHR, claims, and registries Apply pharmacoepidemiologic methods to safety and comparative effectiveness research Provide statistical leadership and scientific input to cross-functional teams and clients What you will need: MSc or PhD in Biostatistics, Statistics, or a related discipline 9+ years' biostatistics experience with an MSc, or 7+ years with a PhD Strong experience in real-world evidence, pharmacoepidemiology, and non-interventional study methodology Proven expertise working with real-world data sources including EHR, claims, and registries Strong R programming skills (essential) Experience authoring and reviewing protocols and Statistical Analysis Plans (SAPs) Solid understanding of biases associated with claims data (particularly US claims) and EHR analyses Experience with study designs such as cohort, self-controlled, and target trial emulation studies Knowledge of analytical methods including propensity scores, clone-censor-weighting, and time-to-event analyses Vaccines and/or infectious disease experience would be advantageous What’s in it for you: Competitive salary + benefits package including medical, dental, vision, pension, fitness subsidy
Principal Statistician in Norfolk employer: Warman O'Brien
Join a leading global biotech organisation that is at the forefront of Oncology innovation, where your expertise as a Senior Medical Science Liaison will be valued and impactful. With a hybrid work model, you will enjoy a flexible work-life balance while being part of a collaborative culture that prioritises employee growth and development through continuous learning opportunities. This role not only offers competitive benefits but also the chance to contribute to groundbreaking advancements in healthcare, making it a truly rewarding career choice.
