At a Glance
- Tasks: Lead a dynamic team in discovering innovative clinical candidates.
- Company: Vertex, a global leader in biotechnology focused on transformative medicines.
- Benefits: Competitive salary, mentorship opportunities, and a vibrant work culture.
- Other info: Join a top-rated workplace with excellent career growth potential.
- Why this job: Make a real impact in drug discovery and help change lives.
- Qualifications: Extensive experience in medicinal chemistry and proven leadership skills.
The predicted salary is between 100000 - 130000 £ per year.
GENERAL SUMMARY: We are seeking a highly motivated and experienced Medicinal Chemistry leader to join our group at Vertex Oxford at the Senior Director level. Reporting to the Head of Medicinal Chemistry, you will lead a highly skilled and motivated medicinal chemistry team to discover high quality clinical candidates that progress into clinical trials. You will have a track record of success across multiple projects from Hit ID to Candidate delivery. You will lead, develop, and implement state of the art medicinal chemistry strategies, providing key expertise in medicinal chemistry and related disciplines (DMPK, biology, computational chemistry, process chemistry). You will help drive the development of our internal talent through continuous teaching and mentorship. You may also take on wider project leadership responsibility, driving a multi-disciplinary project team, accountable to the Site Head for the overall strategy and delivery of a key project within our portfolio.
KEY RESPONSIBILITIES:
- Drive state of the art chemistry design and synthesis to rapidly deliver high-quality clinical candidates.
- Exercise exceptional judgement based on significant medicinal chemistry experience to ensure your team delivers molecules with low predicted human doses and overall profiles that enable rapid progression through pre-clinical safety assessments and into clinical trials.
- Drive and motivate your team of medicinal chemists to deliver molecules using efficient synthetic routes, ensuring smooth transition to scale up teams to enable rapid progress and delivery to project goal timelines.
- Provide dynamic leadership of a multidisciplinary drug-discovery team working on a key project within our portfolio.
SKILLS & EXPERIENCE:
- Qualifications in Organic or Medicinal Chemistry with extensive experience working in a pharmaceutical and/or biotechnology setting as a medicinal chemist.
- Leadership of medicinal chemistry teams with a strong record of scientific accomplishment and success delivering clinical candidates.
- Experience from Hit ID to candidate delivery, with deep knowledge of both molecular properties and drug substance solid form.
- Expert knowledge of medicinal chemistry literature, organic synthesis, and methodology, with good working knowledge of DMPK, biology, computational chemistry, and structure-based drug design.
- A concise and effective communication style to provide teams with clear guidelines, energy, drive, and motivation.
- Strong interpersonal teamwork and organizational skills, with ability to thrive in a dynamic, fast-paced, innovative environment. Ability to manage timelines and drive projects to rapidly answer key questions.
Flex Designation: On-Site Designated
Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.
Company Information: Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
About Vertex: Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has approved medicines that treat the underlying causes of multiple chronic, life-shortening genetic diseases — cystic fibrosis, sickle cell disease and transfusion-dependent beta thalassemia — and continues to advance clinical and research programs in these diseases. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including APOL1-mediated kidney disease, acute and neuropathic pain, type 1 diabetes, myotonic dystrophy type 1 and alpha-1 antitrypsin deficiency.
Founded in 1989 in Cambridge, Mass., Vertex's global headquarters is now located in Boston's Innovation District and its international headquarters is in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 14 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For.
The diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people’s lives.
Our vision is clear: to be the place where an authentic, diverse mix of talent want to come, to stay, and do their best work.
Senior Director, Medicinal Chemistry in Oxford employer: Vertex Pharmaceuticals
Vertex Pharmaceuticals is an exceptional employer that prioritises employee well-being and professional growth. With a flexible hybrid working model, our team enjoys a supportive work culture that fosters collaboration and innovation, while also providing ample opportunities for career advancement in the dynamic field of tax compliance.
StudySmarter Expert Advice🤫
We think this is how you could land Senior Director, Medicinal Chemistry in Oxford
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We think you need these skills to ace Senior Director, Medicinal Chemistry in Oxford
Some tips for your application 🫡
Showcase Your Relevant Experience:When applying for a role in the pharmaceutical industry, it's crucial to highlight any relevant experience you have. Whether that's internships, lab work, or even related coursework, make sure to weave this into your CV and cover letter. We want to see how your background aligns with the role you're applying for at Vertex Pharmaceuticals!
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Tailor Your CV to Be Result-Driven:Craft your CV to highlight quantifiable achievements, especially if you have previous roles in pharmaceuticals or related fields. Use metrics to demonstrate your impact, such as improved processing times or successful project completions while working on trials. This analytical approach will resonate well with hiring managers at Vertex Pharmaceuticals!
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✨Understand the Science
Make sure you brush up on key pharmaceutical concepts and recent developments in the industry. You might get asked some technical questions during the interview at Vertex Pharmaceuticals that show your grasp of drug development processes or regulatory requirements, so be ready to discuss them clearly.
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If you have any hands-on experience or internships in a laboratory setting, be sure to highlight these in your responses. Think about the projects you worked on, the methodologies you used, and the impact you made. It's all about telling a story that connects your background to the role you're applying for.
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In a full-time pharmaceutical role, understanding the regulatory landscape is crucial. Prepare for situational questions that may test your problem-solving skills concerning compliance and safety standards. You could be asked how you'd handle a hypothetical issue regarding a drug’s market release, so think through your approach.
