Find a job 
Featured Companies 
Featured Universities 
For Companies At a Glance
- Tasks: Join a dynamic team to explore cutting-edge research in molecular biology and cell signalling.
- Company: Be part of a diverse university committed to inclusivity and personal development.
- Benefits: Enjoy flexible working arrangements and family-friendly policies.
- Why this job: Contribute to impactful research while developing valuable skills in a collaborative environment.
- Qualifications: PhD in Molecular Biology, Cell Biology or Microbiology required; experience with gene editing is a plus.
- Other info: We encourage applications from underrepresented backgrounds to foster diversity.
The predicted salary is between 36000 - 60000 £ per year.
Applications are invited for a postdoctoral researcher for 36 months to characterise the signalling pathways that regulate autophagy, lysosome exocytosis and biomolecular condensates during the lifecycle differentiations and host adaptation of the African trypanosome T. brucei. The position is funded by a MRC CDA to Dr. Mathieu Cayla who will manage the post. The project will require the use of a wide range of different techniques such as high−throughput live imaging, gene silencing screens, mass spectrometry and murine infection, giving plenty of opportunity to develop transferable skills.
The position requires you to have a PhD in Molecular Biology, Cell Biology or Microbiology. For this multidisciplinary project, you will bring knowledge and expertise in standard molecular biology, -omics studies and imaging techniques. It would be highly desirable to have previous experience in one or more of the following: handling murine models and pathogens of class 2, in protein kinases and signalling, in -omics data analysis, super resolution microscopy and/or live imaging, and CRISPR/Cas9 mediated precision editing.
Key responsibilities- Validate of high−throughput live imaging system combined with gene silencing screen of protein kinases
- Autophagy-related proximity labelling, phospho-proteomic and mass spectrometry analysis
- Assays of protein interaction and enzyme activity using biophysical and biochemical approaches
- Generation of mutated cell lines by CRISPR/Cas9 mediated precision editing and phenotypic validation in vitro and in murine model
- Biomolecular condensate purification and component analysis by mass spectrometry and sequencing
- A PhD in Molecular Biology, Cell Biology or Microbiology
- Knowledge in molecular biology, parasitology, and a range of modern techniques, to engage in high quality research
- Skills and experiences in cell culture, handling of class 2 pathogens, murine infection, and gene editing is desirable
- Excellent track record of research publications and highly developed communication skills
- Attention to detail, collaborative ethos with interest in and enthusiasm for co-supervising students
- Positive attitude to colleagues and students and a willingness to work proactively
- Commitment to personal development and understanding of equality and diversity issues
The University strives to be diverse and inclusive – a place where we can ALL be ourselves. We particularly encourage applications from people who identify as Black, Asian or from a Minority Ethnic background, who are underrepresented at the University. We offer family friendly, flexible working arrangements, with forums and inclusive facilities to support our staff.
Postdoctoral Research Associate employer: University of York
Contact Detail:
University of York Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Postdoctoral Research Associate
✨Tip Number 1
Network with professionals in the field of molecular biology and parasitology. Attend relevant conferences or seminars where you can meet researchers and academics who may have insights into the position or even know Dr. Mathieu Cayla personally.
✨Tip Number 2
Familiarise yourself with the latest research and techniques related to autophagy and lysosome exocytosis. Being well-versed in current literature will not only help you during interviews but also demonstrate your genuine interest in the project.
✨Tip Number 3
Prepare to discuss your previous research experiences in detail, especially any work involving murine models, CRISPR/Cas9, or mass spectrometry. Highlighting specific examples will show your expertise and how it aligns with the job requirements.
✨Tip Number 4
Showcase your collaborative skills by mentioning any past experiences where you worked in a team or co-supervised students. This will resonate well with the emphasis on collaboration and communication in the job description.
We think you need these skills to ace Postdoctoral Research Associate
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights your PhD in Molecular Biology, Cell Biology or Microbiology. Emphasise any relevant experience with techniques mentioned in the job description, such as gene silencing screens, mass spectrometry, and murine models.
Craft a Strong Cover Letter: In your cover letter, express your enthusiasm for the project and how your skills align with the responsibilities outlined. Mention specific experiences that demonstrate your expertise in molecular biology and any relevant research publications.
Highlight Transferable Skills: Discuss any transferable skills you have developed through previous research projects, especially those related to high-throughput live imaging and CRISPR/Cas9 editing. This will show your ability to adapt and contribute to the multidisciplinary nature of the project.
Show Commitment to Diversity: Reflect on your understanding of equality and diversity issues in your application. Mention any experiences that demonstrate your commitment to creating an inclusive environment, which is highly valued by the University.
How to prepare for a job interview at University of York
✨Showcase Your Research Experience
Be prepared to discuss your previous research projects in detail, especially those related to molecular biology and cell biology. Highlight any publications or presentations you've contributed to, as this demonstrates your expertise and commitment to the field.
✨Demonstrate Technical Proficiency
Familiarise yourself with the specific techniques mentioned in the job description, such as CRISPR/Cas9 editing and mass spectrometry. Be ready to explain how you have used these techniques in your past work and how you can apply them to the new role.
✨Emphasise Collaboration Skills
Since the position involves co-supervising students and working within a team, be sure to highlight your collaborative experiences. Share examples of how you've successfully worked with others in research settings and how you handle differing opinions.
✨Express Enthusiasm for the Project
Show genuine interest in the research project and its implications. Discuss why you are passionate about studying T. brucei and how you see your role contributing to the overall goals of the research team.
