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- Tasks: Join a cutting-edge research team to explore genetic drivers of Motor Neurone Disease.
- Company: Be part of the NIHR Sheffield Biomedical Research Centre's innovative research programme.
- Benefits: Enjoy competitive leave, flexible working, and a commitment to your personal development.
- Why this job: Make a real impact in neuroscience while developing your own research projects.
- Qualifications: Background in molecular biology and neuropathology is essential.
- Other info: Diverse and inclusive environment with excellent opportunities for career growth.
The predicted salary is between 30000 - 40000 £ per year.
An exciting opportunity has arisen for a highly motivated postdoctoral researcher with a background in molecular biology and neuropathology, to join our Motor Neurone Disease (MND) / Neurodegeneration clinical research programme. You will have the opportunity to be part of the NIHR Sheffield Biomedical Research Centre (Translational Neuroscience for Chronic Neurological Disorders) Junior Academy and gain an appreciation of a wide variety of translational neuroscience research programmes. The focus of the role will be the neuropathological characterisation of newly identified genetic drivers of MND including CCDC146, WDR49 and ZNF839. All three genetic drivers have been identified through our approach joining cell biology with large scale genotyping via machine learning. Neuropathology is essential to determine the relationship between newly discovered genetic drivers and pathological hallmarks of disease such as mislocalisation of TDP-43. Increasingly we are also utilising cutting‑edge medium‑high throughput technology such as spatial transcriptomics, spatial metabolomics and spatial proteomics. You will also have the opportunity to develop your own research project aligned to the interests of the MND group. This could include new machine learning models or exploring a particular aspect of MND biology.
Responsibilities
- Design, develop and refine methodology for characterisation of new and established neuropathological hallmarks of MND.
- Prepare papers for journals / presentations either in‑house or at national / international conferences or seminars to disseminate research findings.
- Read academic papers, journals and textbooks and attend conferences.
- Contribute to research group planning.
- Coordinate and liaise with other members of the research group over work progress; supervise research team/activities if required.
- Continuously monitor and check results with daily planning to accommodate new developments.
- Plan several months in advance to meet deadlines for journal publications and to prepare presentations and papers for conferences.
- Carry out other duties, commensurate with the grade and remit of the post.
Benefits
We offer a fantastic range of benefits including a highly competitive annual leave entitlement (with the ability to purchase more), a generous pensions scheme, flexible working opportunities, a commitment to your development and wellbeing, a wide range of retail discounts, and much more.
Equal Opportunity Statement
We build teams of people from different heritages and lifestyles from across the world, whose talent and contributions complement each other to greatest effect. We believe diversity in all its forms delivers greater impact through research, teaching and student experience.
Research Associate in Neuropathology and Translational Neuroscience in Sheffield employer: University of Sheffield
Contact Detail:
University of Sheffield Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Research Associate in Neuropathology and Translational Neuroscience in Sheffield
✨Tip Number 1
Network like a pro! Reach out to professionals in the field of neuropathology and neuroscience. Attend conferences, join relevant online forums, and connect with researchers on LinkedIn. You never know who might have the inside scoop on job openings!
✨Tip Number 2
Show off your skills! Prepare a portfolio showcasing your research projects, publications, and any presentations you've done. This will help you stand out during interviews and give potential employers a taste of what you can bring to their team.
✨Tip Number 3
Practice makes perfect! Conduct mock interviews with friends or mentors to refine your responses. Focus on articulating your experience with molecular biology and neuropathology, and be ready to discuss how you can contribute to their research programme.
✨Tip Number 4
Apply through our website! We’ve got a streamlined application process that makes it easy for you to showcase your talents. Plus, it shows you're genuinely interested in joining our team at StudySmarter. Don’t miss out on this opportunity!
We think you need these skills to ace Research Associate in Neuropathology and Translational Neuroscience in Sheffield
Some tips for your application 🫡
Tailor Your CV: Make sure your CV is tailored to highlight your experience in molecular biology and neuropathology. We want to see how your background aligns with the exciting research we're doing at the NIHR Sheffield Biomedical Research Centre.
Craft a Compelling Cover Letter: Your cover letter should tell us why you're passionate about MND and how your skills can contribute to our research programme. Be genuine and let your enthusiasm shine through!
Showcase Your Research Skills: In your application, emphasise any previous research projects you've worked on, especially those involving machine learning or neuropathological techniques. We love seeing how you’ve applied your knowledge in real-world scenarios.
Apply Through Our Website: Don’t forget to apply through our website! It’s the best way for us to receive your application and ensures you’re considered for this fantastic opportunity. We can’t wait to hear from you!
How to prepare for a job interview at University of Sheffield
✨Know Your Research
Make sure you’re well-versed in the latest findings related to Motor Neurone Disease and the specific genetic drivers mentioned in the job description. Familiarise yourself with key papers, especially those by Zhang et al., as they’ll likely come up during your interview.
✨Showcase Your Methodology Skills
Be prepared to discuss your experience with methodologies relevant to neuropathology and translational neuroscience. Highlight any previous work with spatial transcriptomics or machine learning models, as this will demonstrate your fit for the role.
✨Prepare for Team Dynamics
Since collaboration is key in research, think about examples from your past where you’ve successfully worked in a team. Be ready to discuss how you can contribute to group planning and supervise activities, as these are important aspects of the role.
✨Plan Your Questions
Interviews are a two-way street! Prepare thoughtful questions about the research group’s current projects and future directions. This shows your genuine interest and helps you assess if the environment aligns with your career goals.