At a Glance
- Tasks: Design and optimise synthetic routes for small-molecule APIs in a collaborative environment.
- Company: Wilmington PharmaTech, a leader in pharmaceutical innovation.
- Benefits: Competitive salary, professional development, and opportunities for mentorship.
- Other info: Join a dynamic team with excellent career growth potential.
- Why this job: Make a real impact in drug development while working with cutting-edge technology.
- Qualifications: PhD in Organic Chemistry with experience in synthetic organic chemistry.
The predicted salary is between 60000 - 80000 £ per year.
Wilmington PharmaTech (WPT) is seeking a highly skilled Senior Synthetic Organic Chemist, PhD to support the design, development, and optimization of synthetic routes for small-molecule APIs and advanced intermediates. This role will play a critical technical leadership position within process development, contributing deep expertise in organic synthesis, route scouting, and scale-up to support kilo-scale and commercial manufacturing programs. The successful candidate will work cross-functionally with Analytical, Manufacturing, and Quality Assurance teams to deliver robust, scalable, and cost-effective chemical processes. This position reports to the Executive VP of Process Chemistry.
Responsibilities
- Route Scouting & Design: Design, evaluate, and optimize synthetic routes for APIs and key intermediates, balancing efficiency, safety, scalability, and cost considerations.
- Reaction Development: Develop and optimize chemical reactions, including reagent selection, solvent systems, catalysts, and reaction conditions to improve yield, purity, and robustness.
- Process Understanding: Apply strong mechanistic understanding and scientific rationale to guide development decisions and troubleshoot complex synthetic challenges.
- Literature & IP Review: Conduct thorough literature and patent reviews to identify viable synthetic approaches and ensure freedom to operate.
- Technology Transfer: Support the transfer of synthetic processes from laboratory scale to pilot plant and manufacturing environments.
- Scale-Up Execution: Collaborate with manufacturing teams to scale reactions safely and reproducibly, addressing process risks and variability.
- Troubleshooting: Provide hands-on technical support during scale-up, validation, and routine manufacturing to resolve process deviations and performance issues.
- Safety & Risk Assessment: Conduct reaction hazard assessments and contribute to safe process design and implementation.
- Technical Mentorship: Provide scientific guidance and mentorship to junior chemists, fostering technical growth and best practices in the laboratory.
- Innovation & Improvement: Identify opportunities to improve synthetic efficiency, sustainability, and process robustness across development programs.
- Knowledge Sharing: Contribute to internal knowledge bases, best-practice documents, and continuous improvement initiatives within Process Chemistry.
Qualifications
- Education: PhD in Organic Chemistry or a closely related scientific discipline.
- Experience: 0-5+ years of postdoctoral or industry experience in synthetic organic chemistry, process development, or pharmaceutical R&D.
- Technical Expertise: Strong hands-on expertise in complex organic synthesis, reaction optimization, and impurity control for small-molecule APIs.
- Scale-Up Experience: Demonstrated experience supporting scale-up and technology transfer to pilot or commercial manufacturing environments.
- Communication: Excellent written and verbal communication skills, with the ability to clearly document work and communicate technical concepts to cross-functional teams and external stakeholders.
Sr. Analytical Chemists - B.S., M.S., Ph.D. - Wilmington PharmaTech - Posted May 20, 2026 employer: University of Pittsburgh, Department of Chemistry
The U.S.-India TRUST Fellowship at Manipal Institute of Technology offers an exceptional opportunity for postdoctoral researchers to engage in cutting-edge solar fuel technology while enjoying a supportive work environment in the vibrant city of Udupi. With competitive benefits including a monthly stipend, on-campus housing, meals, and health insurance, this fellowship fosters collaboration and innovation, making it an ideal place for professional growth and meaningful contributions to sustainable energy solutions.
Contact Details:
University of Pittsburgh, Department of Chemistry Recruitment Team
