At a Glance
- Tasks: Design and optimise synthetic routes for small-molecule APIs in a collaborative environment.
- Company: Wilmington PharmaTech, a leader in pharmaceutical innovation.
- Benefits: Competitive salary, professional development, and opportunities for mentorship.
- Other info: Join a dynamic team with excellent career growth potential.
- Why this job: Make a real impact in drug development while working with cutting-edge technology.
- Qualifications: PhD in Organic Chemistry with experience in synthetic organic chemistry.
The predicted salary is between 60000 - 80000 £ per year.
Wilmington PharmaTech (WPT) is seeking a highly skilled Senior Synthetic Organic Chemist, PhD to support the design, development, and optimization of synthetic routes for small-molecule APIs and advanced intermediates. This role will play a critical technical leadership position within process development, contributing deep expertise in organic synthesis, route scouting, and scale-up to support kilo-scale and commercial manufacturing programs. The successful candidate will work cross-functionally with Analytical, Manufacturing, and Quality Assurance teams to deliver robust, scalable, and cost-effective chemical processes. This position reports to the Executive VP of Process Chemistry.
Responsibilities
- Route Scouting & Design: Design, evaluate, and optimize synthetic routes for APIs and key intermediates, balancing efficiency, safety, scalability, and cost considerations.
- Reaction Development: Develop and optimize chemical reactions, including reagent selection, solvent systems, catalysts, and reaction conditions to improve yield, purity, and robustness.
- Process Understanding: Apply strong mechanistic understanding and scientific rationale to guide development decisions and troubleshoot complex synthetic challenges.
- Literature & IP Review: Conduct thorough literature and patent reviews to identify viable synthetic approaches and ensure freedom to operate.
- Technology Transfer: Support the transfer of synthetic processes from laboratory scale to pilot plant and manufacturing environments.
- Scale-Up Execution: Collaborate with manufacturing teams to scale reactions safely and reproducibly, addressing process risks and variability.
- Troubleshooting: Provide hands-on technical support during scale-up, validation, and routine manufacturing to resolve process deviations and performance issues.
- Safety & Risk Assessment: Conduct reaction hazard assessments and contribute to safe process design and implementation.
- Technical Mentorship: Provide scientific guidance and mentorship to junior chemists, fostering technical growth and best practices in the laboratory.
- Innovation & Improvement: Identify opportunities to improve synthetic efficiency, sustainability, and process robustness across development programs.
- Knowledge Sharing: Contribute to internal knowledge bases, best-practice documents, and continuous improvement initiatives within Process Chemistry.
Qualifications
- Education: PhD in Organic Chemistry or a closely related scientific discipline.
- Experience: 0-5+ years of postdoctoral or industry experience in synthetic organic chemistry, process development, or pharmaceutical R&D.
- Technical Expertise: Strong hands-on expertise in complex organic synthesis, reaction optimization, and impurity control for small-molecule APIs.
- Scale-Up Experience: Demonstrated experience supporting scale-up and technology transfer to pilot or commercial manufacturing environments.
- Communication: Excellent written and verbal communication skills, with the ability to clearly document work and communicate technical concepts to cross-functional teams and external stakeholders.
Sr. Analytical Chemists - B.S., M.S., Ph.D. - Wilmington PharmaTech - Posted May 20, 2026 employer: University of Pittsburgh, Department of Chemistry
Wilmington PharmaTech is an exceptional employer that fosters a collaborative and innovative work culture, where employees are encouraged to contribute their expertise in synthetic organic chemistry to impactful projects. Located in Newark, Delaware, the company offers competitive benefits, opportunities for professional growth, and a commitment to safety and sustainability, making it an ideal place for chemists looking to advance their careers while making a meaningful difference in the pharmaceutical industry.
Contact Details:
University of Pittsburgh, Department of Chemistry Recruitment Team
StudySmarter Expert Advice🤫
We think this is how you could land Sr. Analytical Chemists - B.S., M.S., Ph.D. - Wilmington PharmaTech - Posted May 20, 2026
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We think you need these skills to ace Sr. Analytical Chemists - B.S., M.S., Ph.D. - Wilmington PharmaTech - Posted May 20, 2026
Some tips for your application 🫡
Show Off Your Lab Skills:When applying for a chemistry position, make sure to highlight any lab experience you've got. Mention specific techniques and instruments you've worked with, as they can set you apart from other candidates. For us, demonstrating your practical skills is as important as your theoretical knowledge!
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How to prepare for a job interview at University of Pittsburgh, Department of Chemistry
✨Know Your Experiments
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