Research Assistant: Neuronal iPSC Biomarker Discovery

Research Assistant: Neuronal iPSC Biomarker Discovery

Full-Time 30000 - 40000 £ / year (est.) No working from home possible
University of Oxford

At a Glance

  • Tasks: Conduct lab experiments and analyse data to discover biomarkers for Parkinson's disease.
  • Company: Join a cutting-edge research team at the Kavli Institute in Oxford.
  • Benefits: Gain hands-on experience, work in a supportive environment, and contribute to meaningful research.
  • Other info: Flexible working arrangements available; we celebrate diversity and inclusion.
  • Why this job: Make a real impact in neuroscience and help advance Parkinson's disease research.
  • Qualifications: BSc/MSc in relevant field and experience in cellular neuroscience or molecular biology.

The predicted salary is between 30000 - 40000 £ per year.

Applications are invited for a Research Assistant neuronal cell biologist to work on a project to discover novel biomarkers of lysosomal dysfunction in Parkinson's disease. The project, funded by the Michael J Fox Foundation and in collaboration with EndLyz, represents an exciting opportunity to undertake translation work at the interface between academic research and pharmaceutical target and drug discovery. This work will develop novel biomarkers to better understand lysosomal dysfunction in Parkinson's by working with induced pluripotent stem cell (iPSC)-derived dopamine neurons generated from Parkinson's patients.

Responsibilities:

  • Undertaking laboratory experiments
  • Interpretation of data
  • Imaging analysis
  • Generation and study of iPSC-derived neurons and cell lines
  • Preparation of data for publication
  • Study biomarker read-outs of endolysosomal dysfunction in cellular models of Parkinson's
  • Contribute to wider project planning and determine the most appropriate methodologies to test hypotheses

You will have excellent practical experience of working with induced pluripotent stem cell cultures and good knowledge of cellular models of neurodegenerative disease. The ability to innovate, troubleshoot technical problems, and be meticulous in practical work and in record keeping is essential.

Recruitment Criteria:

Applicants must hold, or be near completion of, a BSc/MSc in a relevant area of research and have experience in cellular neuroscience or molecular cell biology relevant to analysis of neuronal phenotypes.

Details:

The post is available for 24 months to start on January 1st 2024. The post will be based in the Kavli Institute for Nanoscience Discovery, South Parks Road, Oxford, OX1 3PT.

Inclusion:

Applications are particularly welcome from women, black and minority ethnic candidates who are underrepresented in academic posts in Oxford. While this is a full-time role, we welcome applications from individuals who wish to be considered for part-time working or other flexible working arrangements. We, as a Department and Community, will be considerate and welcoming of all people, regardless of race, ethnicity, religion, disability, sexual orientation and gender identity. We acknowledge societal inequalities and how these impact us, and those around us, personally and professionally.

Research Assistant: Neuronal iPSC Biomarker Discovery employer: University of Oxford

Join a pioneering research environment at the Kavli Institute for Nanoscience Discovery in Oxford, where you will contribute to groundbreaking work in neuronal iPSC biomarker discovery for Parkinson's disease. Our inclusive and supportive culture fosters collaboration and innovation, providing ample opportunities for professional growth and development. With a commitment to diversity and flexible working arrangements, we strive to create a workplace that values every individual's contribution and perspective.

University of Oxford

Contact Details:

University of Oxford Recruitment Team

StudySmarter Expert Advice🤫

We think this is how you could land Research Assistant: Neuronal iPSC Biomarker Discovery

Tip Number 1

Network like a pro! Reach out to your connections in the field of cellular neuroscience or molecular cell biology. Attend relevant events, webinars, or workshops to meet potential collaborators and employers. You never know who might have the inside scoop on job openings!

Tip Number 2

Show off your skills! Prepare a portfolio showcasing your lab work, experiments, and any publications. This will give you an edge during interviews, as it demonstrates your hands-on experience and passion for research. Plus, it’s a great conversation starter!

Tip Number 3

Practice makes perfect! Conduct mock interviews with friends or mentors to refine your responses. Focus on articulating your experience with iPSC cultures and neurodegenerative disease models. The more comfortable you are, the better you'll perform when it counts!

Tip Number 4

Apply through our website! We’ve got a streamlined application process that makes it easy for you to showcase your qualifications. Don’t hesitate to reach out if you have questions about the role or the application process – we’re here to help you land that dream job!

We think you need these skills to ace Research Assistant: Neuronal iPSC Biomarker Discovery

Laboratory Experimentation
Data Interpretation
Imaging Analysis
Induced Pluripotent Stem Cell (iPSC) Cultures
Cellular Models of Neurodegenerative Disease
Biomarker Discovery
Technical Problem-Solving

Some tips for your application 🫡

Tailor Your CV:Make sure your CV highlights your experience in cellular neuroscience and molecular cell biology. We want to see how your skills align with the role, so don’t be shy about showcasing relevant projects or lab work!

Craft a Compelling Cover Letter:Your cover letter is your chance to shine! Use it to explain why you're passionate about discovering biomarkers for Parkinson's disease and how your background makes you a great fit for our team. Keep it engaging and personal!

Showcase Your Technical Skills:Since this role involves a lot of practical lab work, make sure to mention any specific techniques or methodologies you’re familiar with. We love seeing candidates who can innovate and troubleshoot technical problems!

Apply Through Our Website:Don’t forget to submit your application through our website! It’s the best way for us to keep track of your application and ensure it gets the attention it deserves. Plus, we’re excited to see what you bring to the table!

How to prepare for a job interview at University of Oxford

Know Your Science

Make sure you brush up on your knowledge of induced pluripotent stem cells and their role in neurodegenerative diseases. Be ready to discuss specific methodologies you've used in the lab, as well as any relevant findings from your previous research.

Showcase Your Problem-Solving Skills

Prepare examples of how you've tackled technical challenges in your past work. Whether it’s troubleshooting an experiment or innovating a new approach, demonstrating your ability to think critically will impress the interviewers.

Be Meticulous

Since attention to detail is crucial in this role, be prepared to talk about how you maintain accurate records and ensure quality in your experiments. You might even want to bring along a sample of your lab notes to showcase your meticulousness.

Engage with the Project's Goals

Familiarise yourself with the aims of the project funded by the Michael J Fox Foundation. Show genuine interest in how discovering biomarkers can impact Parkinson's research and be ready to share your thoughts on potential methodologies that could be employed.