Senior Postdoctoral Research Assistant in Skin Immunology and Single-cell Genomics in Oxford

Senior Postdoctoral Research Assistant in Skin Immunology and Single-cell Genomics in Oxford

Oxford Full-Time 49199 - 58265 £ / year (est.) No working from home possible
University of Oxford

At a Glance

  • Tasks: Lead innovative research on T cell antigens in GvHD and GvL for blood cancer treatments.
  • Company: Join the prestigious University of Oxford's Kennedy Institute, a leader in biomedical research.
  • Benefits: Enjoy 38 days annual leave, excellent pension, childcare services, and more.
  • Other info: Dynamic, interdisciplinary environment with opportunities for career growth and development.
  • Why this job: Make a real impact in cancer research while collaborating with top scientists.
  • Qualifications: PhD in immunology or related field with strong research and publication record.

The predicted salary is between 49199 - 58265 £ per year.

We are offering an exciting and unique opportunity for an experienced postdoctoral researcher to work on an interdisciplinary, multi-centre project aiming to identify antigens targeted by T cells mediating Graft-versus-Host Disease (GvHD) and Graft-versus-Leukaemia (GvL) following stem cell transplantation (SCT) as a treatment for blood cancers.

In this role you will carry out collaborative projects with colleagues in partner institutions and research groups, and write up experimental results, methodology and interpretation which will contribute to reports when required. You will develop, establish, and pursue appropriate analytical protocols and techniques to support research, including standardized protocols for patient sample flows.

You will also develop research questions within a specific context, conduct individual research, analysing detailed and complex qualitative and/or quantitative data from a variety of sources, and generate original ideas by building on existing concepts. Use initiative and creativity to identify areas for research, adapt existing and develop new research methodologies and extend the research portfolio.

You will ensure the smooth day-to-day running of the laboratory e.g., by ensuring equipment is functioning and monitoring and ordering stock as necessary. Use specialist scientific equipment within the laboratory environment for protocols such as 10X controllers, spatial transcriptomics profilers, PCR machines and flow cytometers.

You will hold a PhD/DPhil in immunology or related area with post-qualification research experience alongside a keen interest in cancer and/or transplantation immunology and/or dermatology. You will have a strong publication record and familiarity with the existing literature and research in the field together with evidence of having collaborated with both wet and dry lab researchers to complete a project.

You will demonstrate experience handling and dissociating human tissues including skin as well as in standard laboratory-based immunology techniques, such as human tissue handling and culture, flow cytometry. You will have demonstrable experience in bioinformatics analysis of omics datasets, e.g. single-cell omics, including single-cell immune repertoire analysis as well as experience and knowledge of R and/or python programming. Proficiency in histopathology work such as tissue sectioning, conducting 10X single-cell RNAseq (wet lab) and conducting spatial transcriptomics (wet lab or data analysis) is desirable.

Location: Kennedy Institute of Rheumatology, Roosevelt Drive, Headington, Oxford OX3 7FY

Salary: Grade 8: Salary in the range of £49,199-£58,265 per annum. This is inclusive of a pensionable Oxford University Weighting of £1,730 per year. This is a full-time (100%), fixed term position until 30/06/2029. A lower grade offer (Grade 7: £39,424 - £47,779 per annum) may be made to a less experienced candidate if a suitable candidate cannot be found to fill the Grade 8 position.

The University of Oxford is a stimulating work environment, which enjoys an international reputation as a world-class centre of excellence. Our research plays a key role in tackling many global challenges, from reducing our carbon emissions to developing vaccines during a pandemic. The Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) is part of the Medical Sciences Division and is the largest European academic department in its field, running a globally competitive programme of research and teaching.

The Kennedy Institute is a biomedical research centre uniquely bringing together discovery science and early-stage clinical research, to develop transformative new therapies for chronic inflammatory and musculoskeletal conditions. The Dendrou group is an interdisciplinary team whose research aims to compare inflammatory diseases and immunological responses across tissues, over time and upon perturbation for translational benefit, leveraging tissue profiling through multiomic technologies in conjunction with cutting-edge computational and machine learning approaches.

As an employer, we genuinely care about our employees' wellbeing and this is reflected in the range of benefits that we offer including:

  • An excellent contributory pension scheme
  • 38 days annual leave
  • A comprehensive range of childcare services
  • Family leave schemes
  • Cycle loan scheme
  • Discounted bus travel and Season Ticket travel loans
  • Membership to a variety of social and sports clubs

Senior Postdoctoral Research Assistant in Skin Immunology and Single-cell Genomics in Oxford employer: University of Oxford

The University of Oxford is an exceptional employer, offering a vibrant research environment that fosters creativity and innovation in neuroscience. With access to cutting-edge facilities and a collaborative work culture, employees are encouraged to grow professionally through various development opportunities. Located in the historic city of Oxford, the university provides a unique blend of academic excellence and cultural richness, making it an ideal place for those seeking meaningful and impactful careers in research.

University of Oxford

Contact Details:

University of Oxford Recruitment Team

StudySmarter Expert Advice🤫

We think this is how you could land Senior Postdoctoral Research Assistant in Skin Immunology and Single-cell Genomics in Oxford

Get Involved in Research Communities

Dive headfirst into the scientific research world by joining relevant communities and forums. Engage in discussions, share your insights, and even attend conferences or seminars in your field. This not only boosts your visibility but can also lead to potential job opportunities—don't forget to connect with like-minded folks!

Show Off Your Research Projects

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Utilise Professional Networks

Networking is key in scientific research. Join professional bodies or organisations related to your field. They often have job boards and resources tailored for job seekers. Make connections with professionals who may know about openings or can give you tips on landing a full-time position.

Keep Your Eyes on Openings & Apply Directly

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We think you need these skills to ace Senior Postdoctoral Research Assistant in Skin Immunology and Single-cell Genomics in Oxford

Communication Skills
Problem-Solving Skills
Compassion
Flexibility
Organizational Skills
Teamwork
Adaptability

Some tips for your application 🫡

Highlight Your Research Experience:When applying for a full-time role in scientific research, make sure to emphasise your research experience prominently in your CV. Share specific projects you’ve worked on, the methodologies you used, and any significant findings. If you’ve published papers or presented at conferences, definitely include that too – it shows you’re on it in the academic world!

Tailor Your Cover Letter to the Research Area:Your cover letter should reflect your passion for the specific area of research at University of Oxford. Mention relevant experiences that align with the organisation’s goals or projects. This shows that you’ve done your homework and are genuinely interested in the position – plus, it helps us see how you’d fit into the team dynamics.

Showcase Your Data Analysis Skills:In scientific research, data analysis skills are a big deal! Make sure to detail any relevant analytical tools or software you’re familiar with, like R, Python, or statistical packages. Employers are keen to know you can handle the data-heavy elements of the role, so add specific examples where you’ve used these skills effectively.

Discuss Your Future Research Goals:In your motivation section, it’s a great idea to talk about your future research goals and how they align with the work being done at University of Oxford. This shows that you’re not just looking for any job, but rather a chance to contribute meaningfully to the field. We love to see applicants who are forward-thinking and enthusiastic about their research journey!

How to prepare for a job interview at University of Oxford

Showcase Your Research Skills

In scientific research, it’s crucial to demonstrate your ability to design and conduct experiments. Come armed with examples of past projects where you've developed hypotheses, collected data, and analysed results. Be ready to discuss any specific methodologies or tools you’ve used, like PCR techniques or statistical software.

Prepare for Technical Questions

Expect some technical questions specific to your field. Make sure you're up to speed with recent advancements in scientific research related to the role at University of Oxford. Brush up on concepts relevant to their projects and be prepared to discuss how you would approach a specific research problem or challenge they might face.

Know Your Publications

If you've authored or co-authored any papers, be prepared to discuss them! Highlighting your contributions to published research can really set you apart. It shows not only your expertise but also your ability to communicate complex ideas clearly, which is key in scientific research roles.

Exhibit Your Team Spirit

In full-time roles, collaboration is often at the heart of scientific research. Prepare examples that show how you've successfully worked in teams, dealt with conflicts, or contributed to group projects. We want to know how you can work effectively with the team at University of Oxford to drive research projects forward.