At a Glance
- Tasks: Explore neuron-astrocyte communication in neurodegeneration and lead innovative research projects.
- Company: Join the prestigious University of Oxford and GSK in a collaborative research environment.
- Benefits: Gain access to cutting-edge resources, mentorship, and opportunities for career advancement.
- Other info: Be part of a dynamic team focused on scientific creativity and multidisciplinary collaboration.
- Why this job: Make a real impact in neuroscience and contribute to groundbreaking discoveries in health.
- Qualifications: PhD/DPhil in relevant fields and hands-on experience with iPSCs and neurodegenerative diseases.
The predicted salary is between 35000 - 44600 £ per year.
Job overview
We are looking for a highly motivated Postdoctoral Research Scientist in neuron-astrocyte communication in neurodegeneration looking to develop an independent research career to join the Lang group (Oxford-GSK IMCM Fellow & NDM Group Leader, University of Oxford).
The Lang Lab is an inclusive environment with a focus on positive and proactive mentorship, teamwork, and scientific creativity.
This post provides an exciting opportunity to join the multidisciplinary Oxford-GSK Institute for Molecular & Computational Medicine (IMCM) operating within Nuffield Department of Medicine (NDM) in collaboration with Nuffield Department of Clinical Neuroscience (NDCN), Sir William Dunn School of Pathology and Department of Physiology, Anatomy and Genetics (DPAG).
The Institute will bring together the very best scientific, clinical, technological and computational expertise from Oxford University and GSK to form unique industry/academic partnership.
The aim of the institute is to improve tools in, and knowledge from, genetics, genomics, molecular and single cell biology, spatial imaging, machine learning and novel methods of data handling to study the pattern of diseases in new ways.
You will be responsible for undertaking a multidisciplinary approach to understand mechanisms of communication between dopamine neurons and astrocytes in health and neurodegenerative disease.
You will perform neuronal and astrocyte differentiation of i PSCs from Parkinson’s patients and controls.
You will perform monocultures and microfluidic co-culture of i PSC-derived dopamine neurons and astrocytes from Parkinson’s patients and controls.
You will utilise transcritpomic approaches to look at gene expression changes to identify proteins/pathways involved in i PSC-derived neuron-astrocyte support or damage.
You will perform extracellular vesicle isolation in biofluids & lentiviral CRISPR-Cas9 knockdown of genes of interest in i PSC-derived dopamine neurons and astrocytes.
You will manage own academic research and administrative activities, including small scale project management and co-ordination of multiple aspects of work to meet deadlines.
It is essential that you hold a Ph D/DPhil (or close to completion) in Neuroscience, Biology, Molecular Biology, Biochemistry, Biomedical Sciences, Genetics/Genomics or related area.
You must have hands-on experience in the differentiation of human induced pluripotent stem cells (i PSCs) into neurons.
You must have experience and knowledge of neurodegenerative diseases, such as Parkinson’s.
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Postdoctoral Research Scientist In Neuron-Astrocyte Communication In Neurodegeneration in Oxford employer: University of Oxford
The University of Oxford is an exceptional employer, offering a vibrant research environment that fosters creativity and innovation in neuroscience. With access to cutting-edge facilities and a collaborative work culture, employees are encouraged to grow professionally through various development opportunities. Located in the historic city of Oxford, the university provides a unique blend of academic excellence and cultural richness, making it an ideal place for those seeking meaningful and impactful careers in research.
StudySmarter Expert Advice🤫
We think this is how you could land Postdoctoral Research Scientist In Neuron-Astrocyte Communication In Neurodegeneration in Oxford
✨Get Involved in Local Research Communities
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We think you need these skills to ace Postdoctoral Research Scientist In Neuron-Astrocyte Communication In Neurodegeneration in Oxford
Some tips for your application 🫡
Show Off Your Lab Skills:In the biotechnology field, it's super important to highlight your lab experience in your CV. Be sure to mention specific techniques or instruments you've mastered (think PCR, gel electrophoresis, etc.) and any relevant projects you've worked on. This will show University of Oxford that you have the hands-on skills they need.
Tailor Your Technical Skills:Make sure to emphasise your technical skills, especially those relevant to the biotechnology sector. Include any software tools or programming languages you've used, like R or Python for data analysis, which could be key for this role at University of Oxford.
Craft a Compelling Cover Letter:Since this is a full-time role, your cover letter should reflect not only your passion for biotechnology but also your long-term career ambitions. Share why you're excited about the work that University of Oxford does and how you envision contributing to their goals. This shows that you’re not just looking for any job, but you're genuinely invested in this opportunity.
Include Your Papers and Projects:If you've published any papers or contributed to significant projects, mention them! These documents can boost your application and provide tangible evidence of your expertise in the biotechnology field. Don’t forget to link to any relevant publications or project summaries—this can set you apart from other candidates.
How to prepare for a job interview at University of Oxford
✨Brush Up on Lab Techniques
Since you're eyeing a full-time gig in biotechnology, make sure you're well-versed in the lab techniques relevant to the role. Be ready to talk about PCR, CRISPR, or any specific methods mentioned in the job description at University of Oxford. You might even be asked to demonstrate your understanding of these processes.
✨Know Your Bioinformatics Tools
Get comfortable with bioinformatics tools that are commonly used in the industry, like BLAST or Bioconductor. These are key in biotechnology, and having hands-on experience or at least familiarity can set you apart. Prepare to discuss any relevant projects you've worked on, especially if they involved data analysis or genomic research.
✨Show Your Teamwork Skills
Biotech often involves collaboration across multiple disciplines. Be ready to share stories that highlight your teamwork and communication skills, especially in research projects. Think about working with different teams at university or any internships – this is where you can show how well you fit into University of Oxford's culture.
✨Research Recent Biotech Innovations
Stay updated on the latest trends and breakthroughs in biotechnology. Knowing what's happening in the field can help you engage in more meaningful discussions during your interview. Bring up recent articles or advancements that excite you, especially those related to the work being done at University of Oxford. This shows your passion for the industry!
