At a Glance
- Tasks: Conduct cutting-edge research in mathematical modelling of osteoarthritis and publish findings.
- Company: Join the prestigious University of Oxford's Mathematical Institute and be part of a renowned research team.
- Benefits: Competitive salary, academic environment, and opportunities for teaching and professional development.
- Other info: Collaborative environment with a commitment to diversity and inclusion.
- Why this job: Make a real impact in healthcare by advancing understanding of osteoarthritis through innovative modelling.
- Qualifications: PhD in a relevant field and strong mathematical modelling skills.
The predicted salary is between 35000 - 45000 £ per year.
We invite applications for a Postdoctoral Research Associate to work with Professor Helen Byrne at the Mathematical Institute, University of Oxford. This is a three-year, fixed-term position, funded by the GSK-Imperial-Oxford Modelling-Informed Medicine Centre (MiMeC). The post is available to start immediately. The successful candidate will be a member of the Wolfson Centre for Mathematical Biology in the Mathematical Institute.
Responsibilities
- The role involves carrying out research involving mathematical modelling of osteoarthritis as part of the MiMeC Osteoarthritis research theme.
- The candidate will develop a multiscale model describing the response of chondrocytes to mechanical and biochemical stimuli, integrating established subcellular signalling pathways that regulate switching between homeostatic and mechano-activated chondrocyte phenotypes, and validating against existing datasets and experimental data from Professor Vincent's group at the Kennedy Institute for Rheumatology.
- In the longer term, the cellular model will be embedded within a pericellular niche to investigate the co-evolution of chondrocyte phenotype and microenvironment during osteoarthritis progression and response to treatment.
- The researcher will contribute to the research and scholarly activities of the Wolfson Centre for Mathematical Biology and write up the results for publication in leading, peer-reviewed journals.
- Opportunities for a small amount of teaching (up to three hours per week during the academic terms) are also available.
Collaboration & Support
The research theme is led by Professors Helen Byrne and Tonia Vincent in Oxford, in close collaboration with Dr Grant Generaux at GSK, and supported by Professor Philip Maini (Oxford), Prabhakar Pandian (GSK) and John Kreeger (GSK).
Commitment
We proudly hold a departmental Athena SWAN Silver Award and an institutional Race Equality Charter Bronze Award.
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We think this is how you could land Postdoctoral Research Associate in Mathematical Modelling of Osteoarthritis in Oxford
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Discuss Your Future Research Goals:In your motivation section, it’s a great idea to talk about your future research goals and how they align with the work being done at University of Oxford. This shows that you’re not just looking for any job, but rather a chance to contribute meaningfully to the field. We love to see applicants who are forward-thinking and enthusiastic about their research journey!
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