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- Tasks: Explore the mechanisms of protein degradation and lead your own research project.
- Company: Join a dynamic research group at the Sir William Dunn School of Pathology, Oxford.
- Benefits: Competitive salary, professional development opportunities, and a supportive environment.
- Why this job: Make a real impact in cell biology and biochemistry while advancing your career.
- Qualifications: PhD in molecular/cell biology, biochemistry, or related field; strong publication record required.
- Other info: Fixed-term contract for 2 years with excellent career growth potential.
The predicted salary is between 39424 - 47779 £ per year.
Location: Sir William Dunn School of Pathology, South Parks Road, Oxford
Contract: Fixed-term contract
We are seeking to appoint a Postdoctoral Research Assistant with a strong interest in addressing fundamental mechanistic questions in cell biology, biochemistry and/or structural biology. You will join a dynamic and supportive research group led by Prof. Pedro Carvalho and will play an active role in shaping the direction of the project.
The position would suit a well-trained, enthusiastic and self-motivated scientist interested in studying the molecular and mechanistic basis of ubiquitin-dependent protein degradation, with a particular emphasis on ERAD of membrane proteins. The project will involve the mechanistic dissection of protein quality control pathways, combining biochemical and cell-biological approaches, and, where appropriate, structural biology.
You will be responsible for managing your own research project while contributing conceptually to the overall research programme. This includes coordinating multiple aspects of the work, refining working hypotheses in light of new data, and contributing ideas for new research directions.
The post-holder should hold, or be close to completion of, a PhD in molecular/cell biology, biochemistry, structural biology or a closely related discipline. You should be able to think critically about experimental design, develop and test hypotheses, and integrate data from multiple approaches to address fundamental biological questions. Strong publication records as well as experience in protein biochemistry, including expression and purification of recombinant protein (membrane proteins in particular) are essential.
This is a fixed-term appointment available for 2 years. If you are interested in this role, and have the skills and experience we are looking for, please apply online. You will be required to upload a CV and supporting statement as part of your online application. Informal enquiries could be sent to Prof Pedro Carvalho via email: pedro.carvalho@path.ox.ac.uk.
The closing date for applications is 12.00 midday on Friday 27 February 2026. Interviews will be held as soon as possible thereafter.
At the Dunn School we are committed to supporting the professional and career development of our postdocs and research staff. To help them thrive and achieve their ambitions, we have created a comprehensive range of opportunities and initiatives designed to provide an exceptional launchpad for their future careers.
£39,424 to £47,779 p.a. Research Grade 7
Postdoctoral Research Assistant - the mechanisms of protein degradation in Oxford employer: University of Oxford
Contact Detail:
University of Oxford Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Postdoctoral Research Assistant - the mechanisms of protein degradation in Oxford
✨Tip Number 1
Network like a pro! Reach out to current or former researchers at the Sir William Dunn School of Pathology. A friendly chat can give you insights into the team culture and might even lead to a referral.
✨Tip Number 2
Prepare for your interview by diving deep into the latest research on ubiquitin-dependent protein degradation. Show us that you're not just familiar with the basics, but that you're genuinely excited about contributing to cutting-edge science.
✨Tip Number 3
Practice your pitch! Be ready to discuss your previous research experiences and how they relate to the project. We want to see your passion and how you can bring your unique skills to the table.
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets seen. Plus, it shows us that you’re serious about joining our dynamic research group.
We think you need these skills to ace Postdoctoral Research Assistant - the mechanisms of protein degradation in Oxford
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights your relevant experience in molecular/cell biology, biochemistry, and structural biology. We want to see how your skills align with the role, so don’t be shy about showcasing your strong publication record and any hands-on experience with protein biochemistry.
Craft a Compelling Supporting Statement: Your supporting statement is your chance to shine! Use it to explain why you’re passionate about the project and how your background makes you a perfect fit. We love seeing enthusiasm and a clear understanding of the research area, so let your personality come through.
Be Clear and Concise: When writing your application, clarity is key. We appreciate straightforward language that gets to the point. Avoid jargon unless it’s necessary, and make sure your ideas flow logically. This will help us understand your thought process better!
Apply Through Our Website: Don’t forget to apply online through our website! It’s the easiest way for us to receive your application. Plus, it ensures you’re following the correct procedure, which we really appreciate. Get your application in before the deadline!
How to prepare for a job interview at University of Oxford
✨Know Your Science
Make sure you brush up on the latest research in protein degradation, especially around ubiquitin-dependent pathways. Be ready to discuss your previous work and how it relates to the project at hand. This shows your genuine interest and expertise.
✨Prepare Your Questions
Think of insightful questions to ask during the interview. This could be about the research group's current projects or future directions. It demonstrates your enthusiasm and critical thinking skills, which are essential for a role like this.
✨Showcase Your Skills
Be prepared to talk about your experience with protein biochemistry, particularly with membrane proteins. Highlight specific techniques you've mastered, such as expression and purification, and how they can contribute to the research goals.
✨Practice Your Presentation
You might be asked to present your previous research or a relevant topic. Keep it clear and concise, focusing on your methodology and findings. Practising will help you communicate your ideas effectively and confidently.
