We are seeking a Postdoctoral Researcher to participate in research in the Quantitative Immunodynamics Laboratory led by Dr. Narain Karedla as part of an ERC Starting Grant project MIETEN (Metal-Induced Energy Transfer based Electrometry and Nanometry). In this role, you will contribute to the ERC-funded MIETEN program by developing and applying quantitative fluorescence microscopy and spectroscopy methods for single‑molecule charge measurements and nanoscale membrane electrostatics.
You will adapt existing scientific techniques and develop new experimental methods to investigate how molecular and membrane electrostatics regulate immune‑cell signalling and immune‑cell–target cell interactions, using engineered substrates, electroactive biointerfaces, and membrane‑mimetic systems. This position involves the use of specialist laboratory equipment, including advanced fluorescence microscopy and spectroscopy platforms such as the PicoQuant Luminosa, to generate, analyse and interpret imaging, fluorescence lifetime, single‑molecule, correlation spectroscopy and other biophysical data.
You must hold a PhD/DPhil (or be near completion) in physics, biophysics, physical chemistry, nanoscience, bioengineering or a closely related discipline, with a strong background in quantitative fluorescence microscopy or spectroscopy and experience in methods related to single‑molecule or membrane biophysics. You should have demonstrable experience in developing, fabricating and characterising engineered substrates, nanoscale devices, electroactive biointerfaces, or thin‑film platforms for optical, electrochemical or biological measurements. You will also have the ability to design, plan and independently manage academic research and associated activities, and evidence of research productivity appropriate to the career stage, including publications, preprints, conference presentations, or other relevant research outputs. Experience with FCS, FLCS, single‑molecule fluorescence, super‑resolution microscopy or photon‑counting/TCSPC methods is desirable.
Grade 7: Salary in the range of £39,424–£43,984 per annum. This is inclusive of a pensionable Oxford University weighting of £1,730 per year. This is a full‑time (100% FTE), fixed‑term position for 3 years.
Benefits
- An excellent contributory pension scheme
- 38 days annual leave
- A comprehensive range of childcare services
- Family leave schemes
- Cycle loan scheme
- Discounted bus travel and season ticket travel loans
- Membership to a variety of social and sports clubs