Postdoc: Autoimmune Neuropathy & B-Cell Immunology in Oxford

Postdoc: Autoimmune Neuropathy & B-Cell Immunology in Oxford

Oxford Full-Time 35000 - 45000 £ / year (est.) No working from home possible
University of Oxford

At a Glance

  • Tasks: Join a cutting-edge research team to study autoimmune neuropathy and B-cell immunology.
  • Company: University of Oxford, renowned for its innovative research in clinical neurosciences.
  • Benefits: Gain invaluable experience across two leading European centres with potential for career advancement.
  • Other info: Collaborate with top researchers and contribute to high-impact projects.
  • Why this job: Make a real impact in the field of autoimmune neurology while developing your scientific expertise.
  • Qualifications: PhD in relevant field and a passion for translational research.

The predicted salary is between 35000 - 45000 £ per year.

This is an exciting opportunity for a highly motivated Post-Doctoral Research Assistant to join the Inflammatory Neuropathy Research Group within the Nuffield Department of Clinical Neurosciences (NDCN), University of Oxford. The post is funded by GBS|CIDP Foundation International as part of a translational research programme entitled "Decoding and monitoring the immunology of multifocal motor neuropathy to guide next-generation, disease-modifying therapies".

The overall aim of the project is to define and track the pathogenic B-cell clones and autoantibodies driving multifocal motor neuropathy (MMN), and to use this knowledge to inform targeted, disease-modifying therapeutic strategies. The project integrates advanced immunophenotyping, single-cell approaches, B-cell receptor sequencing, antibody cloning, in vitro functional assays (including human iPSC-derived motor neuron systems), and longitudinal immune monitoring.

The post-holder will work under the joint supervision of Prof Simon Rinaldi (Oxford) and Dr Nicolas Dubuisson (Oxford/UCLouvain). The first 18 months will be based in Oxford, focusing on detection and characterisation of pathogenic B-cell clones and antibody cloning. The remaining 18 months will be spent at UCLouvain (Belgium), developing downstream antibody production, characterisation, and therapeutic testing pipelines, while remaining employed by the University of Oxford.

The post offers an outstanding opportunity to contribute to a high-impact translational programme, develop independent scientific expertise in autoimmune neurology and B-cell immunology, and gain experience across two leading European centres.

Postdoc: Autoimmune Neuropathy & B-Cell Immunology in Oxford employer: University of Oxford

The Nuffield Department of Clinical Neurosciences at the University of Oxford is an exceptional employer, offering a dynamic work environment that fosters innovation and collaboration in cutting-edge research. With access to world-class facilities and the opportunity to work alongside leading experts in the field, employees benefit from a strong culture of support and professional development, ensuring meaningful contributions to impactful projects in autoimmune neurology. The unique dual-location experience between Oxford and UCLouvain further enriches career growth and networking opportunities within Europe’s top research institutions.

University of Oxford

Contact Details:

University of Oxford Recruitment Team

StudySmarter Expert Advice🤫

We think this is how you could land Postdoc: Autoimmune Neuropathy & B-Cell Immunology in Oxford

Tip Number 1

Network like a pro! Reach out to current and former researchers in the field of autoimmune neurology. A friendly chat can lead to valuable insights and even job leads. Don't be shy; we all love a good conversation about our passions!

Tip Number 2

Showcase your skills! Create a personal website or an online portfolio that highlights your research, publications, and any relevant projects. This is your chance to shine and let potential employers see what you bring to the table. We recommend linking it in your applications!

Tip Number 3

Prepare for interviews by diving deep into the latest research in B-cell immunology and autoimmune neuropathies. Being well-versed in current trends will not only impress your interviewers but also show your genuine interest in the field. We believe knowledge is power!

Tip Number 4

Apply through our website! It’s the easiest way to stay updated on new opportunities and ensures your application gets the attention it deserves. Plus, we’re always looking for passionate individuals to join our team, so don’t miss out!

We think you need these skills to ace Postdoc: Autoimmune Neuropathy & B-Cell Immunology in Oxford

Immunophenotyping
Single-Cell Approaches
B-Cell Receptor Sequencing
Antibody Cloning
In Vitro Functional Assays
Human iPSC-Derived Motor Neuron Systems
Longitudinal Immune Monitoring

Some tips for your application 🫡

Tailor Your CV:Make sure your CV is tailored to highlight your relevant experience in autoimmune neurology and B-cell immunology. We want to see how your skills align with the exciting research we're doing at NDCN!

Craft a Compelling Cover Letter:Your cover letter should tell us why you're passionate about this project and how you can contribute. Be genuine and let your enthusiasm for the role shine through – we love to see that!

Showcase Your Research Skills:In your application, emphasise any previous research experience, especially in immunophenotyping or antibody cloning. We’re looking for someone who can hit the ground running, so don’t hold back on showcasing your expertise!

Apply Through Our Website:We encourage you to apply directly through our website. It’s the best way to ensure your application gets into the right hands. Plus, it shows us you’re keen on joining our team at StudySmarter!

How to prepare for a job interview at University of Oxford

Know Your Research

Dive deep into the specifics of autoimmune neuropathy and B-cell immunology. Familiarise yourself with recent studies, especially those related to multifocal motor neuropathy. This will not only show your passion but also help you engage in meaningful discussions during the interview.

Prepare for Technical Questions

Expect questions about advanced immunophenotyping, single-cell approaches, and antibody cloning. Brush up on your knowledge of these techniques and be ready to discuss how you've applied them in your previous work or how you would approach them in this role.

Showcase Your Collaborative Spirit

Since this position involves working under joint supervision, highlight your experience in collaborative research environments. Share examples of how you've successfully worked with others, particularly in multidisciplinary teams, to achieve common goals.

Ask Insightful Questions

Prepare thoughtful questions about the project and the team dynamics. Inquire about the specific challenges they face in tracking pathogenic B-cell clones or the future direction of the research. This demonstrates your genuine interest and helps you assess if the role is the right fit for you.