Oxford Centre for Diabetes Endocrinology and Metabolism (OCDEM), Churchill Hospital, Old Road, Headington, Oxford, OX3 7LE
An exciting opportunity has arisen for a Computational Biologist to lead the core computational analyses for a British Heart Foundation-funded project investigating how RSPO3 regulates human body fat distribution and cardiometabolic risk.
The study combines recall-by-genotype human phenotyping with single-nucleus RNA sequencing of abdominal and gluteal adipose tissue, large-scale proteomic datasets and genetic analyses. You will analyse and integrate these data to define the cellular and molecular effects of RSPO3 and identify pathways linking adipose tissue biology to cardiometabolic disease.
We are seeking a highly motivated Bioinformatician to lead the core computational analyses for a British Heart Foundation-funded three-year project investigating how RSPO3 regulates human body fat distribution and cardiometabolic risk. The study combines recall-by-genotype human phenotyping with single-nucleus RNA sequencing of abdominal and gluteal adipose tissue, large-scale proteomic datasets and genetic analyses. The postholder will analyse and integrate these data to define the cellular and molecular effects of RSPO3 and identify pathways linking adipose tissue biology to cardiometabolic disease. The appointee will bring strong computational and statistical skills and work closely with experts in adipose tissue biology, single-cell genomics and statistical genetics. The role offers substantial scope for intellectual contribution, method development, first-author publications and presentation of findings at national and international meetings.
The position is full time and fixed term for 3 years in the first instance. The position will be based at OCDEM, Churchill Hospital, Oxford.
For informal enquiries, please contact Ruby Ramsamy at ocdem.personnel@ndm.ox.ac.uk Please quote reference 189348 on all correspondence.
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Computational Biologist in Oxford employer: University of Oxford
The Department of Politics and International Relations at the University of Oxford is an exceptional employer, offering a collaborative and intellectually stimulating environment where finance professionals can thrive. With a commitment to equality, diversity, and inclusion, along with generous benefits such as 38 days of annual leave and a robust family leave scheme, employees are supported in both their professional and personal lives. This role not only provides the opportunity to influence strategic financial decisions within a world-renowned department but also fosters continuous growth and development in a vibrant academic community.
