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- Tasks: Manage sample prep and conduct bioinformatics analyses on heart failure and diabetes research.
- Company: Join the University of Leicester, a leader in innovative health research and diversity.
- Benefits: Enjoy competitive salary, excellent pension, generous leave, and professional development opportunities.
- Why this job: Be part of impactful research that drives discovery in cardiovascular disease and diabetes.
- Qualifications: Experience in proteomics, mass spectrometry, and bioinformatics is essential; diabetes knowledge is a plus.
- Other info: Applications for job share and secondments are welcome; informal enquiries encouraged.
The predicted salary is between 28800 - 48000 £ per year.
Overview
Research Associate in Omics of Heart Failure and Type 2 Diabetes – University of Leicester School of Business. This role is part of the NIHR-BRC Core and Cardiovascular Themes, supporting a dynamic research group with substantial recent grant activity. The position is based at the University of Leicester van Geest Omics facility (Hodgkin Building). The facility hosts NIHR Biomedical Research Centre infrastructure, a BHF Clinical Research Centre, a BHF Accelerator centre award and a 4-year PhD programme, the van Geest MultiOmics facility, and a NIHR Clinical Research Facility including a dedicated 3T MRI research scanner. It is equipped with high-throughput biomarker discovery and translation capabilities, including more than 10 state-of-the-art mass spectrometers, timsTOF HT for plasma proteomics and automation platforms such as Andrew+ and Bravo AssayMAP.
Responsibilities
- Manage sample preparation using automated platforms at the van Geest Omics facility and acquire mass spectrometry data for proteomic and metabolomic analyses of plasma samples from studies on heart failure and type 2 diabetes (e.g., the PREDICT study).
- Perform downstream bioinformatics analyses of high-dimensional omics data and conduct pathway enrichment investigations to delineate the most impacted disease processes in early heart failure within a multi-ethnic type 2 diabetes cohort.
- Design and optimize targeted assays for biomarker candidates using the Waters TQ-XS platform; work to verify and validate biomarkers and biotargets.
- Collaborate with colleagues in the Leicester Diabetes Centre and the Leicester Precision Medicine Institute and with Professors Leong Ng, Don Jones and Gerry McCann on related projects, including multi-centre MRI and plasma sampling studies.
- Support the NIHR Leicester BRC flagship projects and contribute to the overall programme of omics-driven discovery and translation in cardiovascular disease and diabetes.
Qualifications
- Knowledge of proteomic and small molecule sample preparation and mass spectrometric data acquisition for complex downstream bioinformatic pathway analysis is mandatory.
- Knowledge of type 2 diabetes and/or cardiac imaging is desirable.
- The successful candidate will be able to obtain independent funding as a principal investigator and will be encouraged to apply for personal fellowships.
Enquiries
Informal enquiries are welcome and should be directed to Dr Gavin Whyman at gavin.whyman@leicester.ac.uk.
Additional information
- Applications for job share will be considered.
- The role may be considered on a secondment basis for existing staff (discuss with your line manager prior to applying).
- More information regarding secondments can be found on the University’s site.
- The University of Leicester is committed to equality, diversity and inclusion; it offers a competitive salary package, excellent pension and generous annual leave, with opportunities for professional development.
Location: Leicester, England, United Kingdom
The University of Leicester is a diverse and forward-thinking employer that embeds equality, diversity and inclusion in all we do. We strive for wellbeing and sustainability on campus and beyond.
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Research Associate In Omics of Heart Failure and Type 2 Diabetes employer: University of Leicester School of Business
Contact Detail:
University of Leicester School of Business Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Research Associate In Omics of Heart Failure and Type 2 Diabetes
✨Tip Number 1
Familiarise yourself with the latest research in omics related to heart failure and type 2 diabetes. This will not only help you understand the current landscape but also allow you to engage in meaningful conversations during interviews.
✨Tip Number 2
Network with professionals in the field by attending relevant conferences or seminars. Building connections can provide insights into the role and may even lead to referrals, increasing your chances of landing the job.
✨Tip Number 3
Reach out to Dr Gavin Whyman for an informal chat about the position. This shows initiative and gives you a chance to ask specific questions that could set you apart from other candidates.
✨Tip Number 4
Stay updated on advancements in mass spectrometry and bioinformatics tools. Demonstrating your knowledge of these technologies during discussions can highlight your suitability for the role.
We think you need these skills to ace Research Associate In Omics of Heart Failure and Type 2 Diabetes
Some tips for your application 🫡
Understand the Role: Read the job description thoroughly to grasp the responsibilities and qualifications required for the Research Associate position. Highlight your relevant experience in proteomics, bioinformatics, and any knowledge of type 2 diabetes or cardiac imaging.
Tailor Your CV: Customise your CV to reflect the skills and experiences that align with the job requirements. Emphasise your expertise in mass spectrometry, sample preparation, and any previous research projects related to cardiovascular disease or diabetes.
Craft a Compelling Cover Letter: Write a cover letter that not only outlines your qualifications but also expresses your enthusiasm for the role and the research being conducted at the University of Leicester. Mention specific projects or initiatives that resonate with you.
Highlight Collaborative Experience: Since the role involves collaboration with various institutes and colleagues, make sure to include examples of past teamwork and how you contributed to successful research outcomes. This will demonstrate your ability to work effectively in a dynamic research environment.
How to prepare for a job interview at University of Leicester School of Business
✨Showcase Your Technical Skills
Make sure to highlight your experience with mass spectrometry and bioinformatics during the interview. Be prepared to discuss specific projects where you've managed sample preparation or conducted pathway enrichment analyses, as these are crucial for the role.
✨Demonstrate Collaborative Spirit
This position involves working closely with various teams and institutes. Share examples of past collaborations and how you contributed to team success, especially in multi-centre studies or projects related to heart failure and diabetes.
✨Prepare for Questions on Current Research
Familiarise yourself with recent advancements in omics research related to cardiovascular disease and type 2 diabetes. Being able to discuss current trends and how they relate to the work at the University of Leicester will show your enthusiasm and knowledge.
✨Ask Insightful Questions
Prepare thoughtful questions about the research group's ongoing projects and future directions. This not only shows your interest in the role but also helps you gauge if the environment aligns with your career goals.
