At a Glance
- Tasks: Investigate Bacillus spores germination using cutting-edge microfluidics and microscopy techniques.
- Company: University of Exeter’s Living Systems Institute, in partnership with Defence Science and Technology Laboratory.
- Benefits: Fully funded PhD with home tuition fees and a tax-free stipend of at least £22,442.
- Other info: Gain interdisciplinary training and work with leading experts in the field.
- Why this job: Make a real impact on environmental challenges and develop innovative decontamination strategies.
- Qualifications: Degree in Biological Sciences; expertise in Microbiology, Biophysics, or Biotechnology preferred.
The predicted salary is between 21442 - 21442 € per year.
The University of Exeter’s Living Systems Institute is inviting applications for a PhD studentship titled “Understanding Bacillus Spores Germination via microfluidics‑based single‑cell microscopy”. This PhD studentship is fully funded by the Defence Science and Technology Laboratory in partnership with the University of Exeter Faculty of Health and Life Sciences and will commence on 21 September 2026 or as soon as possible thereafter.
For eligible students, the studentship will cover home tuition fees plus an annual tax‑free stipend of at least £22,442 for 3.5 years full‑time, or pro‑rata for part‑time study. The student would be based in the Living Systems Institute in the Faculty of Health and Life Sciences at the Streatham Campus in Exeter.
This fully funded PhD studentship will focus on the investigation of the processes that allow germination of Bacillus anthracis spores. Bacillus anthracis spores cause environmental contamination challenges, primarily due to their considerable resistance to therapeutic intervention and conventional decontamination agents. Their dormant state allows prolonged survival, rendering remediation efforts difficult and costly.
This proposed fully funded PhD project aims to employ microfluidics‑based microscopy to visualise the germination process and understand the mechanisms that allow B. anthracis spore germination after an initial optimisation phase carried out using Bacillus thuringiensis. Microfluidics, a rapidly evolving technology, offers precision and control over cellular microenvironments, enabling real‑time, single‑cell analysis of biological processes. This technology is not restricted by the limitations of traditional bulk assays, which can obscure heterogeneity within spore populations.
By determining the mechanisms that make B. anthracis spores germinate, this project will open the way for transforming highly resistant spores into a vulnerable state, making them susceptible to inactivation. Therefore, this project will develop and validate innovative treatments and decontamination strategies that are more effective, less toxic, and environmentally sound.
This project is particularly suitable for candidates with a degree in Biological Sciences and expertise in Microbiology, Biophysics, Biochemistry or Biotechnology. Expertise in culturing and handling bacteria would be particularly valuable. Previous experience in using microscopy or microfluidics would also be helpful.
This position is only open to UK nationals. The successful applicant will need to obtain clearance from Dstl to work on the project. This project will provide the student with highly interdisciplinary training and expertise which will be very valuable for their future career.
Supervision will be provided by Prof Stefano Pagliara and Dr Remy Chait, at the University of Exeter with expertise in microbiology, microscopy and microfluidics and by Dr Phil Ireland and Dr Graham Christie at the Defence Science and Technology Laboratory and at the University of Cambridge with expertise in Bacillus anthracis and the biology of spore germination.
PhD Studentship: PhD Opportunity TitlePhD in Complex Living Systems - Understanding Bacillus Sp[...] in Exeter employer: University of Exeter
The University of Exeter’s Living Systems Institute offers an exceptional environment for PhD candidates, providing fully funded studentships that include a generous stipend and comprehensive training in cutting-edge research techniques. Located in the vibrant city of Exeter, students benefit from a collaborative work culture that fosters innovation and interdisciplinary learning, alongside opportunities for professional growth through mentorship from leading experts in microbiology and microfluidics. This unique position not only supports academic excellence but also contributes to meaningful advancements in environmental health and safety.
StudySmarter Expert Advice🤫
We think this is how you could land PhD Studentship: PhD Opportunity TitlePhD in Complex Living Systems - Understanding Bacillus Sp[...] in Exeter
✨Tip Number 1
Network like a pro! Reach out to current or former PhD students at the University of Exeter or in similar fields. They can give you insider info on the application process and what the supervisors are really looking for.
✨Tip Number 2
Prepare for interviews by diving deep into the research area. Familiarise yourself with Bacillus spores and microfluidics. The more you know, the more confident you'll feel when discussing your ideas and how you can contribute to the project.
✨Tip Number 3
Showcase your skills! If you've got experience in microbiology or microscopy, make sure to highlight that in conversations. Bring examples of your work or projects to discuss during interviews to really impress the panel.
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets seen. Plus, we’re here to support you every step of the way, so don’t hesitate to reach out if you have questions.
We think you need these skills to ace PhD Studentship: PhD Opportunity TitlePhD in Complex Living Systems - Understanding Bacillus Sp[...] in Exeter
Some tips for your application 🫡
Tailor Your Application:Make sure to customise your application to highlight your relevant skills and experiences. We want to see how your background in Biological Sciences, Microbiology, or related fields aligns with the PhD project on Bacillus spores.
Showcase Your Passion:Let us know why you're excited about this research opportunity! Share your enthusiasm for microbiology and how you see yourself contributing to the understanding of Bacillus anthracis germination.
Be Clear and Concise:Keep your application straightforward and to the point. We appreciate clarity, so make sure your writing is easy to follow and free from jargon that might confuse us.
Apply Through Our Website:Don’t forget to submit your application through our official website. It’s the best way to ensure we receive all your materials and can consider you for this exciting PhD studentship!
How to prepare for a job interview at University of Exeter
✨Know Your Bacillus
Make sure you brush up on your knowledge of Bacillus spores, especially Bacillus anthracis and Bacillus thuringiensis. Understanding their germination processes and the challenges they pose will show your genuine interest in the project and impress the interviewers.
✨Familiarise with Microfluidics
Since this PhD involves microfluidics-based microscopy, it’s crucial to have a solid grasp of this technology. If you’ve had any hands-on experience or coursework related to microfluidics, be ready to discuss it in detail during the interview.
✨Highlight Relevant Experience
If you have experience in microbiology, biophysics, or biochemistry, make sure to highlight it. Discuss any relevant projects or research you've done, particularly those involving microscopy or bacterial culturing, as these will be key to your success in this role.
✨Prepare Questions for Your Interviewers
Interviews are a two-way street! Prepare thoughtful questions about the project, the team, and the training opportunities available. This not only shows your enthusiasm but also helps you gauge if this PhD is the right fit for you.
