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- Tasks: Join a dynamic lab to explore paediatric brain tumours and contribute to groundbreaking research.
- Company: Be part of the Cancer Research UK Cambridge Institute, a leader in cancer research.
- Benefits: Enjoy a collaborative environment with opportunities for professional growth and skill development.
- Why this job: Make a real impact in cancer research while working with cutting-edge techniques and technologies.
- Qualifications: B.Sc. or M.Sc. in Biomedical Sciences, Oncology, or Neuroscience required; lab experience preferred.
- Other info: This is a fixed-term role for 2 years, ideal for motivated individuals eager to learn.
The predicted salary is between 28800 - 48000 £ per year.
Overview
We are seeking a motivated and skilled in vitro Research Assistant to join the group of Professor Richard Gilbertson at the Cancer Research UK Cambridge Institute. The Gilbertson lab is dedicated to understanding the origins and progression of paediatric brain tumours and developing new therapeutic strategies. The lab combines genetic engineering, molecular biology, and translational research to investigate the cellular and molecular mechanisms driving tumour development.
Responsibilities
- In this role, you will support Dr Cooper, using genetically engineered mouse models (GEMMs) and transplantable tumour models (e.g., immunocompetent orthotopic allotransplantation models) to study the role of the immune system in tumour biology and therapeutic response.
- You will play a key role in immunophenotyping a broad array of tissues across our spontaneous mouse models, following functional perturbation experiments in vivo or ex vivo, as well as working collaboratively with postdoctoral researchers, students, and other research staff in the group.
- Conducting detailed necropsies and dissociation of mouse tissues for downstream flow cytometry and molecular analysis
- Perform spectral flow cytometry on mouse tissues and downstream analysis
- Performing cell culture and in vitro immune cell assays
- Performing high-plex immunohistochemical staining of mouse and human tissue
- Conduct confocal imaging of immunofluorescent staining of mouse tissues
- Conducting detailed necropsies and tissue dissections for downstream molecular analyses
- Maintaining accurate and organised records of experimental studies and ensure data is captured in lab databases
- Complying with all regulatory requirements including Home Office licences, local AWERB oversight, and institutional biosafety and welfare protocols
Qualifications
- The successful candidate will hold a B.Sc. or M.Sc. in a relevant discipline (e.g., Biomedical Sciences, Immunology, Oncology, or Neuroscience), and a Home Office Personal Licence (Modules A, B and C or equivalent).
- They should have demonstrable experience in a range of in vitro and ex vivo techniques, including flow cytometry, cell culture, immunohistochemistry and immunofluorescence staining. Proficiency in performing mouse necropsies is preferred, but not essential.
- The ideal candidate will be proactive, adaptable, and capable of working effectively under pressure, with excellent communication skills and a strong focus on teamwork and accurate data recording.
- This position offers the opportunity to contribute directly to impactful cancer research in a dynamic and supportive team.
- Fixed-term: The funds for this post are available for 18 months in the first instance.
Additional information
- Once an offer of employment has been accepted, the successful candidate will be required to undergo a basic disclosure (criminal records check) check and a security check.
- Click the \’Apply\’ button below to register an account with our recruitment system (if you have not already) and apply online.
- Informal enquiries may be made to Elizabeth.cooper@cruk.cam.ac.uk
- Please quote reference SW48729 on your application and in any correspondence about this vacancy.
- The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
- The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
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Research Assistant (Gilbertson Group) (Fixed Term) employer: University of Cambridge
Contact Detail:
University of Cambridge Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Research Assistant (Gilbertson Group) (Fixed Term)
✨Tip Number 1
Familiarise yourself with the specific research projects currently being undertaken in the Gilbertson lab. Understanding their focus on paediatric brain tumours and the techniques they employ will help you tailor your discussions during interviews.
✨Tip Number 2
Network with current or former members of the Gilbertson group or similar research environments. Engaging with them can provide insights into the lab culture and expectations, which can be invaluable when preparing for your application.
✨Tip Number 3
Demonstrate your problem-solving skills by preparing examples of past challenges you've faced in a lab setting. Be ready to discuss how you approached these issues and what the outcomes were, as this is crucial for the role.
✨Tip Number 4
Showcase your adaptability and teamwork skills by highlighting experiences where you successfully collaborated on projects or adapted to new techniques. This will resonate well with the lab's fast-paced environment.
We think you need these skills to ace Research Assistant (Gilbertson Group) (Fixed Term)
Some tips for your application 🫡
Understand the Role: Read the job description thoroughly to understand the specific skills and experiences required for the Research Assistant position. Highlight your relevant qualifications, such as your B.Sc. or M.Sc. in Biomedical Sciences, Oncology, or Neuroscience.
Craft a Tailored Cover Letter: Write a cover letter that specifically addresses how your background and skills align with the responsibilities of the role. Mention your experience with molecular techniques and any relevant laboratory work, showcasing your problem-solving abilities and adaptability.
Highlight Relevant Experience: In your CV, emphasise any practical laboratory experience you have, particularly in techniques mentioned in the job description like RNA extraction, qRT-PCR, and cell culture. Include any in vivo studies if applicable, and ensure your IT and communication skills are clearly stated.
Follow Application Instructions: Make sure to upload your CV and cover letter in the specified format. Avoid including any additional documents that are not requested, as these will not be considered. Remember to quote reference SW46581 in your application.
How to prepare for a job interview at University of Cambridge
✨Show Your Passion for Research
Make sure to express your enthusiasm for the research being conducted in the Gilbertson lab. Discuss any relevant projects or experiences that have ignited your interest in paediatric brain tumours and how you can contribute to their mission.
✨Demonstrate Technical Skills
Be prepared to discuss your hands-on experience with molecular techniques such as RNA extraction, qRT-PCR, and Western blotting. Highlight specific instances where you've successfully applied these skills in a lab setting.
✨Emphasise Problem-Solving Abilities
Since the role requires troubleshooting technical challenges, share examples of how you've approached and resolved issues in previous research projects. This will showcase your critical thinking and adaptability.
✨Prepare Questions About the Lab
Have thoughtful questions ready about the Gilbertson lab's current projects and future directions. This shows your genuine interest in the role and helps you assess if it's the right fit for you.
