Overview
Senior Principal Statistical Programmer (RWE) – 12-Month Freelance Contract
Location: Munich, Bavaria, Germany (100% remote within EU/UK possible)
Contract Duration: 12 months (full-time, 40h/week)
Start Date: ASAP (target September 2025)
Role Overview
We are seeking an experienced Senior Principal Statistical Programmer with expertise in Real-World Evidence (RWE) , R/SAS programming , and R Shiny development . This role involves leading statistical programming for real-world data (RWD) projects and developing interactive applications to support decision-making, regulatory, and HTA submissions.
Key Responsibilities
Lead programming and statistical analysis for RWE projects using EMR, claims, and registry data.
Design, develop, and maintain R Shiny applications for visualization and dissemination of analytical results.
Ensure high-quality, reproducible outputs aligned with project timelines and regulatory standards.
Collaborate with cross-functional teams (HEOR, Biostatistics, Data Science, Medical, Market Access) to scope, interpret, and present results.
Contribute to programming standards, reproducibility frameworks, and code review practices .
Essential Qualifications & Requirements
Advanced degree in Biostatistics, Statistics, Data Science, or HEOR .
Proven hands-on experience with real-world data (EMR, claims, registries) .
Strong programming expertise in R and SAS for RWE analyses.
Proficiency in R Shiny app development for interactive visualization.
Excellent communication skills, with the ability to engage both technical and non-technical stakeholders.
Availability to commit full-time (5 days/week) for the contract duration.
Preferred Skills
Experience supporting regulatory, HTA, or pricing submissions .
Knowledge of OMOP/OHDSI or other common data models.
Familiarity with reproducible workflows (Git), documentation standards, and code review processes .
Understanding of data privacy/GDPR compliance in secondary data usage.
Exposure to cloud-based analytics (AWS, Azure) and deployment of R Shiny applications.
Ideal Candidate Profile
This role is ideal for a principal-level RWE programmer who is comfortable working across complex real-world datasets, can deliver decision-ready insights, and has strong technical expertise in R, SAS, and Shiny . The right candidate will be equally skilled in technical coding, methodological rigor, and effective communication with stakeholders.
Seniority level
Mid-Senior level
Employment type
Contract
Job function
Information Technology
Industries
Pharmaceutical Manufacturing
Biotechnology Research
Hospitals and Health Care
Senior Principal Statistical Programmer (RWE) in London employer: Unity Systems
Unity Systems is an attractive employer due to its focus on innovation and employee development. The company provides competitive salaries and opportunities for remote work, fostering a flexible and supportive work culture. Employees are encouraged to engage in continuous learning, enhancing their skills and career prospects.
