At a Glance
- Tasks: Lead the development of innovative ocular disease models and bioassays.
- Company: Join a cutting-edge CRO focused on human-relevant disease models.
- Benefits: Opportunity to make a real impact in drug discovery and scientific innovation.
- Other info: Dynamic role with potential for team growth and career advancement.
- Why this job: Be at the forefront of reducing animal testing with advanced lab techniques.
- Qualifications: Experience with iPSC-derived systems and strong lab skills in bioassays.
The predicted salary is between 45000 - 60000 £ per year.
We are seeking an Ophthalmology Bioassay Senior Scientist to join a growing, innovative CRO environment focused on developing next-generation human-relevant disease models. This role sits at the forefront of moving drug discovery away from traditional animal models, with a strong emphasis on advanced in vitro systems, including iPSC-derived models and 3D organoids for ocular diseases. You will play a key role in building and developing capability in ophthalmology, contributing to both project delivery and the longer-term growth of this area of the business. This is an excellent opportunity for someone who enjoys combining hands-on lab work, scientific innovation, and commercial impact.
Responsibilities
- Ocular Model Development
- Develop and optimise human-relevant ocular disease models
- Design and implement iPSC-derived systems, including retinal and epithelial models
- Contribute to the development of complex 3D organoid and co-culture systems
- Assay Development & Delivery
- Design and execute bioassays relevant to ocular disease, including:
- Imaging and fluorescence-based assays
- Immunoassays
- Functional and translational assays
- Analyse and interpret experimental data and present findings clearly to stakeholders
- Molecular & Cell Biology
- Apply molecular biology techniques including:
- Gene knockdown approaches (e.g. siRNA, shRNA)
- Work with primary cells, cell lines, and stem-cell derived models
- Support development of increasingly complex and physiologically relevant systems
- Project Delivery & Growth
- Support delivery of CRO projects across drug discovery programmes
- Troubleshoot experimental challenges and drive continuous improvement
- Contribute to building and scaling ophthalmology capability, including future team growth
- Engage with clients and support scientific discussions where required
About You
You are a scientist with strong hands-on experience in advanced cellular models particularly within ophthalmology or closely related disease areas. You'll bring:
- Experience working with iPSC-derived systems and/or 3D organoid models (critical)
- Strong laboratory experience across bioassays, imaging, and molecular biology techniques
- Experience working with ocular models or strong transferable cell biology experience
- A proactive, problem-solving mindset with the ability to work independently
Desirable (but not essential)
- PhD in Ophthalmology, Cell Biology, Stem Cell Biology, or a related discipline
- Experience in a CRO or fast-paced applied research environment
- Exposure to replacing or reducing animal models with human-relevant systems
- Interest in helping build or grow a new scientific capability or team
If you're excited by organoids, stem cell models, and reducing reliance on animal testing, this role will give you the platform to make a real impact.
Ophthalmology iPSC & Organoid Bioassay Lead employer: United Cerebral Palsy of Georgia
Join a pioneering CRO in Nottingham, where innovation meets impact in the field of ophthalmology. We foster a collaborative work culture that values scientific creativity and offers ample opportunities for professional growth, allowing you to contribute to meaningful advancements in drug discovery while working with cutting-edge technologies. With a commitment to reducing reliance on traditional animal models, this role not only enhances your skills but also positions you at the forefront of transformative research.
Contact Details:
United Cerebral Palsy of Georgia Recruitment Team
StudySmarter Expert Advice🤫
We think this is how you could land Ophthalmology iPSC & Organoid Bioassay Lead
✨Network Like a Pro
Get out there and connect with people in the industry! Attend conferences, workshops, or even local meet-ups. You never know who might have the inside scoop on job openings or can put in a good word for you.
✨Show Off Your Skills
When you get the chance to chat with potential employers, make sure to highlight your hands-on experience with iPSC-derived systems and 3D organoids. Share specific examples of your work that demonstrate your problem-solving mindset and innovative approach.
✨Tailor Your Approach
Don’t just send out generic applications! Tailor your conversations and presentations to align with the company’s focus on reducing reliance on animal models. Show them you’re genuinely interested in their mission and how you can contribute.
✨Apply Through Our Website
We’ve got some fantastic opportunities waiting for you! Make sure to apply through our website to ensure your application gets the attention it deserves. Plus, it’s a great way to stay updated on new roles as they come up.
We think you need these skills to ace Ophthalmology iPSC & Organoid Bioassay Lead
Some tips for your application 🫡
Tailor Your CV:Make sure your CV highlights your experience with iPSC-derived systems and 3D organoid models. We want to see how your skills align with our focus on innovative ocular disease models, so don’t hold back!
Craft a Compelling Cover Letter:Your cover letter is your chance to shine! Share your passion for reducing reliance on animal testing and how you can contribute to our mission. Let us know why you're excited about this role and what you can bring to the team.
Showcase Your Lab Skills:We’re looking for hands-on experience, so be sure to mention any relevant lab techniques you've mastered, especially in bioassays and molecular biology. Highlight specific projects where you’ve made an impact!
Apply Through Our Website:Don’t forget to apply through our website! It’s the best way for us to receive your application and ensures you’re considered for this exciting opportunity. We can’t wait to hear from you!
How to prepare for a job interview at United Cerebral Palsy of Georgia
✨Know Your Models
Make sure you brush up on your knowledge of iPSC-derived systems and 3D organoid models. Be ready to discuss specific techniques you've used in the lab, as well as any challenges you've faced and how you overcame them.
✨Showcase Your Problem-Solving Skills
Prepare examples that highlight your proactive, problem-solving mindset. Think about times when you had to troubleshoot experimental challenges and how your solutions contributed to project success.
✨Engage with the Science
Be prepared to discuss recent advancements in ocular disease models and how they relate to drug discovery. Showing genuine interest in the field will demonstrate your passion and commitment to the role.
✨Communicate Clearly
Practice presenting your findings clearly and concisely. You might be asked to explain complex data or concepts, so being able to communicate effectively with stakeholders is key to making a great impression.