At a Glance
- Tasks: Join us in building the world's first automated airlock for health research environments.
- Company: UK Biobank, a leader in biomedical data technology.
- Benefits: Enjoy 26 days of annual leave, healthcare cash plan, and a £500 training budget.
- Other info: Flexible working hours and a supportive team culture focused on personal growth.
- Why this job: Make a real impact on global health research with cutting-edge AI and cloud technologies.
- Qualifications: Experience in full-stack development, Python, TypeScript, and AWS services required.
The predicted salary is between 70000 - 75000 £ per year.
Help build the world’s first automated “airlock” for health research environments. At UK Biobank, we’re developing new technologies that will help researchers securely work with some of the world’s richest biomedical datasets. This role sits within a team building what is believed to be the world’s first automated output checking system for trusted research environments using AI and cloud-native technologies to help ensure researchers can only export files regarded as safe. It’s a genuinely greenfield engineering challenge, combining AI-driven approaches, secure cloud-native architecture, and modern full-stack development to support global health research.
You’ll play a leading role in the development, integration, and delivery of UK Biobank’s Automated Output Checking System, helping shape a platform that supports secure research at a global scale. Working closely with architects, researchers, vendors, and internal engineering teams, you’ll help design and build scalable integrations across research platforms and cloud-native services. This role combines hands-on engineering, technical leadership, and modern platform design, requiring someone who can work confidently across backend services, frontend applications, infrastructure, APIs, and cloud environments. The solution applies AI techniques, follows cloud-native principles, and is being built from the ground up giving you the opportunity to influence both architecture and technical direction.
Responsibilities
- Ensuring integration patterns align with enterprise architecture principles, including event-driven, API-first, and microservices-based approaches.
- Designing and developing scalable, secure, cost-efficient and maintainable full-stack applications using Python (backend) and TypeScript (frontend), including relational and non-relational database management systems on AWS.
- Developing responsive and accessible user interfaces using modern frontend frameworks (e.g., React with TypeScript).
- Developing and managing infrastructure using Infrastructure as Code (Terraform), ensuring reproducible and auditable environments; develop CI/CD pipelines to enable continuous integration, testing, and deployment.
- Ensuring systems are designed with observability, logging, and monitoring to support operational excellence.
Qualifications
- Full-stack software development within enterprise environments.
- Backend development using Python frameworks such as FastAPI, Flask, or similar.
- Frontend development experience using TypeScript and modern frameworks such as React or Vue.
- AWS services (e.g., IAM, S3, Lambda, ECS/EKS, API Gateway, Step Functions).
- Microservices architecture and distributed systems.
- Designing and consuming secure APIs with CI/CD pipelines and DevOps tooling.
Working hours are 35 hours per week, Monday to Friday, with some flexibility, 2 days onsite with hybrid working available. Located in Greater Manchester (initially based in Stockport with a move to Manchester Science Park mid to late 2026).
Our passion for diversity and equality means creating a work environment for all employees that is welcoming, respectful, engaging, and enriched with opportunities for personal and professional development. We actively welcome applications from people with disabilities, long-term health conditions, neurodivergent candidates, and those with diverse thinking styles. We are committed to making reasonable adjustments throughout our recruitment process and in the workplace so that everyone can perform at their best. If you require any adjustments during the recruitment process, please contact Tommy Wilson jobs@ukbiobank.ac.uk so we can support you.
Your Wellbeing Matters to Us
Our wellbeing score on Indeed is rated as 77% (High), reflecting how people experience working here day-to-day. Colleagues often highlight a strong sense of purpose, supportive team culture, and the opportunity to grow. There’s a real focus on learning, flexibility, and feeling valued, whether that’s developing new skills, contributing ideas, or building a career within Data & Technology.
Benefits
- 26 Days’ Annual Leave – Plus Bank Holidays
- Holiday Buy Scheme
- Birthday Leave
- USS Pension Scheme
- Healthcare Cash Plan
- Enhanced Family Leave
- Cycle to Work Scheme
- Season Ticket Loan
- Professional Subscriptions
- £500 annual training budget
- Free On-Site Gym
- Subsidised Canteen Lunches
- Free Car Parking
- Employee Discounts Portal
- Employee Assistance Programme
- Annual Flu Vaccination
- Life Assurance Cover
Senior Full Stack Developer in Manchester employer: UK Biobank Limited
At UK Biobank, we pride ourselves on being an exceptional employer, offering a dynamic work environment in Cheadle that fosters innovation and collaboration. Our commitment to employee wellbeing is reflected in our high satisfaction ratings, comprehensive benefits package, and a culture that prioritises diversity, personal growth, and professional development. Join us to be part of groundbreaking projects that not only advance your career but also contribute to global health research.
StudySmarter Expert Advice🤫
We think this is how you could land Senior Full Stack Developer in Manchester
✨Tip Number 1
Network like a pro! Reach out to your connections in the tech industry, especially those who work at UK Biobank or similar organisations. A friendly chat can lead to insider info about the role and even a referral!
✨Tip Number 2
Show off your skills! Prepare a portfolio showcasing your best full-stack projects, especially those using Python and TypeScript. This will give you a chance to demonstrate your expertise and creativity during interviews.
✨Tip Number 3
Get ready for technical interviews! Brush up on your knowledge of microservices, cloud-native architecture, and CI/CD pipelines. Practice coding challenges and system design questions to impress the interviewers.
✨Tip Number 4
Apply through our website! It’s the best way to ensure your application gets noticed. Plus, it shows you’re genuinely interested in joining the team at UK Biobank and contributing to groundbreaking health research.
We think you need these skills to ace Senior Full Stack Developer in Manchester
Some tips for your application 🫡
Tailor Your CV:Make sure your CV reflects the skills and experiences that match the Senior Full Stack Developer role. Highlight your experience with Python, TypeScript, and AWS, as well as any relevant projects that showcase your full-stack capabilities.
Craft a Compelling Cover Letter:Use your cover letter to tell us why you're passionate about this role and how your background aligns with our mission at UK Biobank. Share specific examples of your work in AI-driven approaches or cloud-native technologies to grab our attention.
Showcase Your Projects:If you've worked on any interesting projects, especially those involving microservices or modern frontend frameworks, make sure to include them in your application. We love seeing real-world applications of your skills!
Apply Through Our Website:For the best chance of getting noticed, apply directly through our website. It helps us keep track of your application and ensures you’re considered for this exciting opportunity to shape the future of health research.
How to prepare for a job interview at UK Biobank Limited
✨Know Your Tech Stack
Make sure you’re well-versed in the technologies mentioned in the job description, especially Python and TypeScript. Brush up on your knowledge of frameworks like FastAPI and React, as well as AWS services. Being able to discuss these confidently will show that you’re ready to hit the ground running.
✨Showcase Your Problem-Solving Skills
Prepare to discuss specific challenges you've faced in previous projects, particularly those involving full-stack development or cloud-native architectures. Use the STAR method (Situation, Task, Action, Result) to structure your answers and highlight how you approached and solved complex problems.
✨Understand the Company’s Mission
Familiarise yourself with UK Biobank's goals and the significance of their work in health research. Be ready to articulate how your skills can contribute to their mission of securely handling biomedical datasets. This shows genuine interest and alignment with their values.
✨Ask Insightful Questions
Prepare thoughtful questions about the team dynamics, project timelines, and the technologies they use. This not only demonstrates your enthusiasm for the role but also helps you gauge if the company culture aligns with your expectations.