At a Glance
- Tasks: Investigate epigenetic changes linked to environmental aerosol exposures in cancer research.
- Company: UCL Cancer Institute, a leader in innovative cancer research.
- Benefits: Competitive salary, collaborative environment, and opportunities for professional growth.
- Other info: Join a dynamic team with access to cutting-edge bioinformatics facilities.
- Why this job: Make a real impact on cancer research and contribute to groundbreaking studies.
- Qualifications: PhD in bioinformatics or related field; strong analytical skills required.
The predicted salary is between 40000 - 50000 £ per year.
TRACERx is supported by the excellent bioinformatics facilities already available in our Centre together with substantial investment in bioinformatics staff, data storage and computer processing power. TRACERx has been highly successful; as of 2023, sequencing data from more than 400 patients have been fully analysed resulting in a flow of high-impact publications, including manuscripts in Nature, Cell, Science and New England Journal of Medicine.
PEACE is a pan cancer national research autopsy programme in which post-mortem sampling allows access to tissue from all sites of metastasis, and to date has recruited over 390 patients and performed over 240 autopsies. The combination of both TRACERx and PEACE with patient co-recruitment has established an unprecedented resource of multi-regional matched primary and metastatic tissue, and therefore facilitates tissue- and blood-based analyses from diagnosis to death.
We are seeking a collaborative and self‑motivated bioinformatician post‑doctoral fellow to work on investigating epigenetic alterations linked to different environmental aerosol exposures. Our previous work identified air pollutants associated with lung cancer promotion; however, the potential health risks associated with other aerosol exposures have not yet been well studied.
Prof Nnenna Kanu leads the Genome Plasticity laboratory at the UCL Cancer Institute and is the Chief Scientific Officer of the Cancer Research UK Lung Cancer Centre of Excellence. This project aims to analyse how immune cells respond to environmental aerosol exposures over time using WGS/RNA/ATAC/DNA methylation sequencing and the consequent metabolomic changes in immune and epithelial cells. The candidate will study how environmental aerosol exposures affect specific immune cells in mouse lung cancer models and analyse relevant published human data. Environmental aerosol exposures‑associated changes in human blood will be compared to early cancer signs observed in mice.
The position will be available for 2 years in the first instance, with the possibility of extension depending on funding availability. Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at Research Assistant Grade 6B.
Research Fellow - Bioinformatics - Environmental Carcinogens / Tumour Evolution Scientist in London employer: UCL
Contact Detail:
UCL Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Research Fellow - Bioinformatics - Environmental Carcinogens / Tumour Evolution Scientist in London
✨Tip Number 1
Network like a pro! Reach out to professionals in the bioinformatics field, especially those connected to TRACERx and PEACE. Attend conferences or webinars where you can meet potential colleagues and mentors – it’s all about making those connections!
✨Tip Number 2
Show off your skills! Prepare a portfolio showcasing your previous research, especially any work related to environmental carcinogens or tumour evolution. This will help you stand out during interviews and demonstrate your hands-on experience.
✨Tip Number 3
Practice makes perfect! Conduct mock interviews with friends or mentors to refine your responses. Focus on how your background aligns with the goals of the TRACERx and PEACE projects, and be ready to discuss your approach to tackling complex bioinformatics challenges.
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets noticed. Plus, we love seeing candidates who are proactive and engaged with our mission at StudySmarter.
We think you need these skills to ace Research Fellow - Bioinformatics - Environmental Carcinogens / Tumour Evolution Scientist in London
Some tips for your application 🫡
Tailor Your CV: Make sure your CV is tailored to the role of Research Fellow in Bioinformatics. Highlight your relevant experience, especially any work related to environmental carcinogens or tumour evolution. We want to see how your skills align with our exciting projects!
Craft a Compelling Cover Letter: Your cover letter should tell us why you're passionate about this research area. Share specific examples of your previous work and how it relates to the TRACERx and PEACE projects. We love seeing enthusiasm and a clear connection to our mission!
Showcase Your Technical Skills: Don’t forget to mention your technical skills, especially in bioinformatics tools and techniques like WGS, RNA sequencing, and data analysis. We’re looking for someone who can hit the ground running, so make sure we know what you bring to the table!
Apply Through Our Website: We encourage you to apply through our website for a smooth application process. It’s the best way to ensure your application gets into the right hands. Plus, it shows us you’re keen on joining our team at StudySmarter!
How to prepare for a job interview at UCL
✨Know Your Research
Dive deep into the specifics of TRACERx and PEACE projects. Familiarise yourself with their methodologies, findings, and publications. Being able to discuss these in detail will show your genuine interest and understanding of the work being done.
✨Showcase Your Skills
Prepare to discuss your experience with bioinformatics tools and techniques relevant to the role, such as WGS, RNA sequencing, and data analysis. Bring examples of past projects where you've successfully applied these skills, especially in relation to environmental exposures or cancer research.
✨Collaborative Spirit
This role emphasises collaboration, so be ready to share examples of how you've worked effectively in teams. Highlight any interdisciplinary projects you've been part of, especially those involving bioinformatics and cancer biology.
✨Ask Insightful Questions
Prepare thoughtful questions about the lab's current projects, future directions, and the team dynamics. This not only shows your enthusiasm but also helps you gauge if the environment is the right fit for you.