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- Tasks: Drive innovative non-clinical PKPD strategies and collaborate with diverse teams.
- Company: Join UCB, a global biopharmaceutical leader focused on neurology and immunology.
- Benefits: Enjoy a supportive culture, hybrid work, and opportunities for personal growth.
- Why this job: Make a real impact on patient outcomes through cutting-edge drug development.
- Qualifications: PhD in relevant fields and expertise in PKPD methods required.
- Other info: Be part of a caring team that values collaboration and innovation.
The predicted salary is between 36000 - 60000 £ per year.
We are looking for a Principal Scientist, Non-Clinical PKPD, who is innovative and agile to join us in our Clinical Development Sciences Group, based at the R&D site in Slough, UK, then Windlesham, Surrey (2027).
About The Role
The Non-Clinical PKPD group sits within the Quantitative Clinical Pharmacology (QCP) function of Early Clinical Development & Translational Science (ECD-TS) Department. Our goal is to use integrated quantitative approaches as an essential strategic driver from target to market to bring differentiated solutions to patients. We are driving the quantitative integrated strategy of pharmacokinetics and pharmacology (e.g. PKPD, Systems modelling and clinical pharmacology/pharmacometrics) together with DMPK activities throughout the entirety of the lifetime of projects, from target identification through to life cycle management.
Who You’ll Work With
We operate and collaborate closely with colleagues in Development Sciences, which, as a department, is responsible for providing strategy and support in bioanalysis, immunogenicity, safety, pathology, and regulatory activities. Work with external partners, academic institutions, CROs and consultants as required.
What You’ll Do
- Develop and drive the nonclinical PKPD strategy for projects, communicating effectively ensuring implementation in projects.
- Ensure translation from in vitro data and in vivo nonclinical studies to prediction of efficacy and safety in patients.
- Initiate and engage in multifunctional collaborations to facilitate the advancement of drug candidates and build a thorough knowledge of drug pharmacology and PKPD, leading to quantitative translation to the clinic.
- Build PKPD models of sufficient complexity to allow hypothesis testing and inform decision-making.
- Represent the interests of QCP internally and externally in matters relevant to mechanistic PKPD and contribute to enhancing the scientific reputation of Non-Clinical PKPD, QCP and UCB.
- Provide required support and input into regulatory study protocols, reports and summaries, and regulatory submission documents.
Interested? For this role you will need the following education, experience and skills:
- PhD in relevant discipline (pharmacology, pharmaceutical sciences, pharmacokinetics/pharmacodynamics, system biology or related fields).
- Good understanding of pharmacology and pharmacologic processes related to disease and drug mechanisms.
- Expertise and proven application of PKPD methods and concepts in support of drug discovery and development; systems modelling experience would be advantageous.
- Demonstrated experience in developing and executing effective non-clinical PKPD strategies from early discovery through to clinic.
- Demonstrated experience and leadership skills working within a matrix environment with a wide range of internal stakeholders including Non-Clinical Safety, Bioanalysis, Clinical Pharmacology and Translational Medicine.
- Experience in using modelling and simulation packages such as Phoenix, Berkeley Madonna, R and Monolix.
Are you ready to ‘go beyond’ to create value and make your mark for patients? If this sounds like you, then we would love to hear from you!
About Us
UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are over 9,000 people in all four corners of the globe, inspired by patients and driven by science.
Why work with us?
At UCB, we don’t just complete tasks, we create value. We aren’t afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equal opportunities to do their best work. We ‘go beyond’ to create value for our patients, and always with a human focus, whether that’s on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential. At UCB, we’ve embraced a hybrid-first approach to work, bringing teams together in local hubs to foster collaborative curiosity. Unless expressly stated in the description or precluded by the nature of the position, roles are hybrid with 40% of your time spent in the office.
UCB is an equal opportunity employer. All employment decisions will be made without regard to any characteristic protected by applicable laws. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on EMEA-Reasonable_Accommodation@ucb.com. Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.
Principal Scientist PK/PD in Slough employer: UCB
Contact Detail:
UCB Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Principal Scientist PK/PD in Slough
✨Tip Number 1
Network like a pro! Reach out to your connections in the industry, especially those who work at UCB or similar companies. A friendly chat can sometimes lead to insider info about job openings or even a referral.
✨Tip Number 2
Prepare for interviews by diving deep into PKPD concepts and recent advancements in pharmacology. We want you to showcase your expertise and passion, so practice articulating how your skills align with UCB's mission to create value for patients.
✨Tip Number 3
Don’t just wait for job postings! Keep an eye on our website and apply directly. Sometimes, roles are filled before they’re even advertised, so being proactive can give you an edge.
✨Tip Number 4
Follow up after interviews with a thank-you note. It’s a simple gesture that shows your enthusiasm for the role and keeps you fresh in the interviewers' minds. Plus, it’s a great way to reiterate your fit for the Principal Scientist position!
We think you need these skills to ace Principal Scientist PK/PD in Slough
Some tips for your application 🫡
Tailor Your CV: Make sure your CV reflects the skills and experiences that align with the Principal Scientist role. Highlight your expertise in PKPD methods and any relevant projects you've worked on, as this will show us you're a great fit for our team.
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to tell us why you're passionate about pharmacology and how your background makes you the perfect candidate. Don't forget to mention your innovative approach and any collaborative experiences you've had.
Showcase Your Technical Skills: We want to see your technical prowess! Be sure to include any experience with modelling and simulation packages like Phoenix or R. This will help us understand how you can contribute to our quantitative integrated strategy.
Apply Through Our Website: We encourage you to apply directly through our website. It’s the best way for us to receive your application and ensures you’re considered for the role. Plus, it shows us you’re keen to join our team at UCB!
How to prepare for a job interview at UCB
✨Know Your PKPD Inside Out
Make sure you have a solid grasp of pharmacokinetics and pharmacodynamics concepts. Brush up on your understanding of drug mechanisms and how they relate to disease. Be ready to discuss specific examples from your past work where you've applied these principles.
✨Showcase Your Collaboration Skills
Since this role involves working with various internal and external stakeholders, prepare to share experiences that highlight your ability to collaborate effectively. Think of instances where you’ve led or contributed to cross-functional teams and how that impacted project outcomes.
✨Demonstrate Your Modelling Expertise
Familiarise yourself with the modelling and simulation packages mentioned in the job description, like Phoenix or R. Be prepared to discuss how you've used these tools in previous projects, including any challenges you faced and how you overcame them.
✨Prepare for Regulatory Discussions
Understand the regulatory landscape related to non-clinical PKPD strategies. Be ready to talk about your experience with regulatory submissions and how you’ve contributed to study protocols or reports. This will show that you’re not just technically skilled but also aware of the broader implications of your work.