At a Glance
- Tasks: Analyse patient-level molecular data to generate insights for clinical assets.
- Company: Join a leading clinical bioinformatics group in Slough, UK.
- Benefits: Competitive salary, flexible working, and opportunities for professional growth.
- Other info: Collaborative environment with opportunities to publish and present your work.
- Why this job: Make a real impact on patient outcomes through innovative bioinformatics.
- Qualifications: Master/PhD with 8+ years of experience in bioinformatics and omics data analysis.
The predicted salary is between 60000 - 80000 £ per year.
Make your mark for patients. We are looking for a Principal Clinical Bioinformatician who is innovative and agile to join our Clinical Bioinformatics Group in Slough, UK (Windlesham, Surrey from 2027).
About the role: To support generation of insights for clinical assets through understanding of mode of action and treatment effects as seen in patient-level molecular data.
Who you’ll work with: Working with a high level of autonomy, you will report to Head of Clinical Bioinformatics.
What you’ll do:
- With minimal guidance of senior staff, processes, analyzes and interprets data from omics studies for assets in the clinical portfolio, to refine understanding of biological mechanisms, disease pathobiology, characterise treatment effect, safety signals and other relevant insights.
- Develops approaches, methods, analysis pipelines utilizing state-of-the-art tools and technologies to enable the above.
- Documents code, analyses and ensure reproducibility of results according to best practices suited to patient-level data.
- Draft reports detailing methods and results that require minimal revision.
- Drafts/contributes to scientific publications that present the results of these analyses (conference abstracts/presentations and manuscripts).
Interested? For this role you need the following education, experience and skills:
- Master/PhD with 8+ years of experience, preferably with industry experience.
- Expertise in pre-processing, integration and analysis of different omics data types, in particular extensive experience analysing large bulk and single-cell RNAseq datasets from complex studies (preferably clinical trials), and experience deriving relevant biological insights from these.
- Experience with spatial data, epigenomics and proteomics is also desirable.
- Expertise in the development and application of methods pertinent for functional interpretation of omics data e.g. pathway enrichment, functional module detection, causal reasoning.
- Experience analyzing and deriving insights using large omics datasets from clinical trials and relating omics data results to clinical variables is a plus.
- Excellent computational skills, such as experience of operating in a HPC Unix environment, cloud-based computational and/or pipelining platforms, and containerization technologies (e.g., Docker) for reproducible and portable bioinformatics workflows.
- Experience using DNAnexus is a plus.
- Proficiency using R and other programming languages common to the bioinformatics community.
- Ability to document code and follow coding best practices, in particular suited to patient-level data, to ensure reproducibility of results.
- Good understanding of statistics, data mining, and visualization of biological data types and the standard tools used in these domains.
- Ability to interpret and communicate efficiently (orally and with reports) the outcomes of analytical work to both expert and non-expert scientific audience to foster efficient decision-making.
- Preferably experience in authoring scientific publications.
Are you ready to ‘go beyond’ to create value and make your mark for patients? If this sounds like you, then we would love to hear from you!
Principal Clinical Bioinformatician (UK) in Slough employer: UCB
Join a forward-thinking organisation that prioritises innovation and patient impact, where as a Principal Clinical Bioinformatician in Slough, you will enjoy a collaborative work culture that fosters autonomy and creativity. With access to cutting-edge technologies and a commitment to employee development, you will have ample opportunities for professional growth while contributing to meaningful projects that directly benefit patients. Our supportive environment encourages scientific exploration and the sharing of ideas, making it an ideal place for those looking to make a significant difference in the field of bioinformatics.
StudySmarter Expert Advice🤫
We think this is how you could land Principal Clinical Bioinformatician (UK) in Slough
✨Tip Number 1
Network like a pro! Reach out to professionals in the bioinformatics field on LinkedIn or at conferences. A friendly chat can lead to opportunities that aren’t even advertised yet.
✨Tip Number 2
Show off your skills! Create a portfolio showcasing your projects, especially those involving omics data analysis. This gives potential employers a taste of what you can do and sets you apart from the crowd.
✨Tip Number 3
Prepare for interviews by brushing up on common bioinformatics questions and case studies. Practising how to explain your analytical methods and results will help you communicate effectively with both experts and non-experts.
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets seen by the right people. Plus, we love hearing from passionate candidates who want to make a difference for patients.
We think you need these skills to ace Principal Clinical Bioinformatician (UK) in Slough
Some tips for your application 🫡
Tailor Your CV:Make sure your CV reflects the skills and experiences that match the job description. Highlight your expertise in omics data analysis and any relevant projects you've worked on. We want to see how you can make an impact!
Craft a Compelling Cover Letter:Your cover letter is your chance to shine! Use it to explain why you're passionate about bioinformatics and how your background aligns with our mission. Be sure to mention specific experiences that demonstrate your innovative approach.
Showcase Your Technical Skills:Don’t forget to highlight your computational skills, especially with tools like R, DNAnexus, and Docker. We’re looking for someone who can hit the ground running, so make sure we know what you bring to the table!
Apply Through Our Website:We encourage you to apply directly through our website. It’s the best way for us to receive your application and ensures you’re considered for this exciting opportunity. Let’s make your mark together!
How to prepare for a job interview at UCB
✨Know Your Data Inside Out
Make sure you’re well-versed in the types of omics data relevant to the role. Brush up on your experience with RNAseq datasets and be ready to discuss specific projects where you derived insights from complex studies. This will show your depth of knowledge and how you can contribute to the team.
✨Showcase Your Technical Skills
Be prepared to talk about your computational skills, especially in HPC Unix environments and cloud-based platforms. If you've used tools like Docker or DNAnexus, highlight these experiences. Demonstrating your technical prowess will reassure them that you can handle the demands of the role.
✨Communicate Clearly and Effectively
Practice explaining your analytical work in simple terms. You’ll need to convey complex ideas to both experts and non-experts, so think of examples where you’ve successfully communicated your findings. This will showcase your ability to foster efficient decision-making within the team.
✨Prepare for Questions on Publications
If you have authored scientific publications, be ready to discuss them in detail. Talk about the methodologies you used and the insights gained. If you haven’t published yet, think of how you would approach writing a paper based on your analyses. This shows your commitment to contributing to the scientific community.
