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For Companies At a Glance
- Tasks: Analyse and interpret patient-level molecular data to generate clinical insights.
- Company: Join UCB, a global biopharmaceutical leader in neurology and immunology.
- Benefits: Enjoy a hybrid work model, competitive salary, and opportunities for professional growth.
- Why this job: Make a real impact on patient care through innovative bioinformatics solutions.
- Qualifications: Master/PhD with 8+ years of experience in bioinformatics and omics data analysis.
- Other info: Collaborative culture focused on inclusion, respect, and equal opportunities.
The predicted salary is between 43200 - 72000 £ per year.
We are looking for a Principal Clinical Bioinformatician who is innovative and agile to join our Clinical Bioinformatics Group in Slough, UK, (Windlesham, Surrey from 2027).
About The Role
To support generation of insights for clinical assets through understanding of mode of action and treatment effects as seen in patient‑level molecular data.
Who You’ll Work With
Working with a high level of autonomy, you will report to Head of Clinical Bioinformatics.
What You’ll Do
- With minimal guidance of senior staff, processes, analyzes and interprets data from omics studies for assets in the clinical portfolio, to refine understanding of biological mechanisms, disease pathobiology, characterise treatment effect, safety signals and other relevant insights.
- Develops approaches, methods, analysis pipelines utilizing state‑of‑the‑art tools and technologies to enable the above.
- Documents code, analyses and ensure reproducibility of results according to best practices suited to patient‑level data.
- Draft reports detailing methods and results that require minimal revision.
- Drafts / contributes to scientific publications that present the results of these analyses (conference abstracts/presentations and manuscripts).
Interested?
For this role you need the following education, experience and skills:
- Master/PhD with 8+ years of experience, preferably with industry experience.
- Expertise in pre‑processing, integration and analysis of different omics data types, in particular extensive experience analysing large bulk and single‑cell RNAseq datasets from complex studies (preferably clinical trials), and experience deriving relevant biological insights from these.
- Experience with spatial data, epigenomics and proteomics is also desirable.
- Expertise in the development and application of methods pertinent for functional interpretation of omics data e.g. pathway enrichment, functional module detection, causal reasoning.
- Experience analysing and deriving insights using large omics datasets from clinical trials and relating omics data results to clinical variables is a plus.
- Excellent computational skills, such as experience of operating in a HPC Unix environment, cloud‑based computational and/or pipelining platforms, and containerization technologies (e.g., Docker) for reproducible and portable bioinformatics workflows.
- Experience using DNAnexus is a plus.
- Proficiency using R and other programming languages common to the bioinformatics community.
- Ability to document code and follow coding best practices, in particular suited to patient‑level data, to ensure reproducibility of results.
- Good understanding of statistics, data mining, and visualization of biological data types and the standard tools used in these domains.
- Ability to interpret and communicate efficiently (orally and with reports) the outcomes of analytical work to both expert and non‑expert scientific audience to foster efficient decision‑making.
- Preferably experience in authoring scientific publications.
Are you ready to ‘go beyond’ to create value and make your mark for patients? If this sounds like you, then we would love to hear from you!
About Us
UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are over 9,000 people in all four corners of the globe, inspired by patients and driven by science.
Why work with us?
At UCB, we don’t just complete tasks, we create value. We aren’t afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equal opportunities to do their best work. We ‘go beyond’ to create value for our patients, and always with a human focus, whether that’s on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential. At UCB, we’ve embraced a hybrid‑first approach to work, bringing teams together in local hubs to foster collaborative curiosity. Unless expressly stated in the description or precluded by the nature of the position, roles are hybrid with 40% of your time spent in the office.
UCB is an equal opportunity employer. All employment decisions will be made without regard to any characteristic protected by applicable laws. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on EMEA‑Reasonable_Accommodation@ucb.com. Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.
Principal Clinical Bioinformatician (UK) employer: UCB
Contact Detail:
UCB Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Principal Clinical Bioinformatician (UK)
✨Tip Number 1
Network like a pro! Reach out to professionals in the bioinformatics field on LinkedIn or at conferences. A friendly chat can lead to opportunities that aren’t even advertised yet.
✨Tip Number 2
Show off your skills! Create a portfolio showcasing your projects, especially those involving omics data analysis. This gives potential employers a taste of what you can do and sets you apart from the crowd.
✨Tip Number 3
Prepare for interviews by brushing up on common bioinformatics questions and case studies. Practising how to explain complex concepts simply will help you connect with both technical and non-technical interviewers.
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets seen by the right people. Plus, it shows you’re genuinely interested in joining our team.
We think you need these skills to ace Principal Clinical Bioinformatician (UK)
Some tips for your application 🫡
Tailor Your Application: Make sure to customise your CV and cover letter to highlight your relevant experience in clinical bioinformatics. We want to see how your skills align with the role, so don’t hold back on showcasing your expertise in omics data analysis!
Showcase Your Projects: Include specific examples of projects you've worked on that demonstrate your ability to analyse and interpret complex datasets. We love seeing how you’ve applied your knowledge in real-world scenarios, especially if it relates to clinical trials.
Keep It Clear and Concise: When drafting your application, clarity is key! Use straightforward language and avoid jargon where possible. We appreciate a well-structured application that’s easy to read and gets straight to the point.
Apply Through Our Website: Don’t forget to submit your application through our website! It’s the best way for us to receive your details and ensures you’re considered for the role. Plus, it shows you’re keen to join our team at UCB!
How to prepare for a job interview at UCB
✨Know Your Data Inside Out
Make sure you’re well-versed in the types of omics data relevant to the role. Brush up on your experience with RNAseq datasets and be ready to discuss specific projects where you derived insights from complex studies. This will show that you can hit the ground running.
✨Showcase Your Technical Skills
Be prepared to talk about your computational skills, especially in HPC Unix environments and cloud-based platforms. If you’ve used tools like Docker or DNAnexus, highlight these experiences. Demonstrating your technical prowess will set you apart from other candidates.
✨Communicate Clearly and Effectively
Practice explaining complex bioinformatics concepts in simple terms. You’ll need to convey your findings to both expert and non-expert audiences, so being able to communicate clearly is key. Consider preparing a few examples of how you've done this in the past.
✨Prepare for Questions on Collaboration
Since the role involves working with autonomy but also collaborating with senior staff, think of examples where you’ve successfully worked in teams. Be ready to discuss how you foster collaboration and innovation in your previous roles, as this aligns with the company’s values.