At a Glance
- Tasks: Drive innovative non-clinical PKPD strategies and collaborate with diverse teams.
- Company: UCB, a global biopharmaceutical leader focused on neurology and immunology.
- Benefits: Hybrid work model, supportive culture, and opportunities for career growth.
- Other info: Join a caring team that values collaboration, innovation, and inclusivity.
- Why this job: Make a real impact on patients' lives through cutting-edge research and development.
- Qualifications: PhD in relevant field and expertise in PKPD methods and systems modelling.
The predicted salary is between 63000 - 77000 £ per year.
We are looking for a Principal Scientist, Non-Clinical PKPD, who is innovative and agile to join us in our Clinical Development Sciences Group, based at the R&D site in Slough, UK, then Windlesham, Surrey (2027).
About the role
The Non-Clinical PKPD group sits within the Quantitative Clinical Pharmacology (QCP) function of Early Clinical Development & Translational Science (ECD-TS) Department. Our goal is to use integrated quantitative approaches as an essential strategic driver from target to market to bring differentiated solutions to patients. We are driving the quantitative integrated strategy of pharmacokinetics and pharmacology (e.g. PKPD, Systems modelling and clinical pharmacology/pharmacometrics) together with DMPK activities throughout the entirety of the lifetime of projects, from target identification through to life cycle management.
Who you’ll work with
We operate and collaborate closely with colleagues in Development Sciences, which, as a department, is responsible for providing strategy and support in bioanalysis, immunogenicity, safety, pathology, and regulatory activities. Work with external partners, academic institutions, CROs and consultants as required.
What you’ll do
- Develop and drive the nonclinical PKPD strategy for projects, communicating effectively to ensure implementation in projects.
- Ensure translation from in vitro data and in vivo nonclinical studies to prediction of efficacy and safety in patients.
- Initiate and engage in multifunctional collaborations to facilitate the advancement of drug candidates and build a thorough knowledge of drug pharmacology and PKPD, leading to quantitative translation to the clinic.
- Build PKPD models of sufficient complexity to allow hypothesis testing and inform decision-making.
- Represent the interests of QCP internally and externally in matters relevant to mechanistic PKPD and contribute to enhancing the scientific reputation of Non-Clinical PKPD, QCP and UCB.
- Provide required support and input into regulatory study protocols, reports and summaries, and regulatory submission documents.
Interested? For this role you will need the following education, experience and skills:
- PhD in relevant discipline (pharmacology, pharmaceutical sciences, pharmacokinetics/pharmacodynamics, system biology or related fields).
- Good understanding of pharmacology and pharmacologic processes related to disease and drug mechanisms.
- Expertise and proven application of PKPD methods and concepts in support of drug discovery and development; systems modelling experience would be advantageous.
- Demonstrated experience in developing and executing effective non-clinical PKPD strategies from early discovery through to clinic.
- Demonstrated experience and leadership skills working within a matrix environment with a wide range of internal stakeholders including Non-Clinical Safety, Bioanalysis, Clinical Pharmacology and Translational Medicine.
- Experience in using modelling and simulation packages such as Phoenix, Berkeley Madonna, R and Monolix.
Are you ready to ‘go beyond’ to create value and make your mark for patients? If this sounds like you, then we would love to hear from you!
About us
UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are over 9,000 people in all four corners of the globe, inspired by patients and driven by science.
Why work with us?
At UCB, we don’t just complete tasks, we create value. We aren’t afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equal opportunities to do their best work. We ‘go beyond’ to create value for our patients, and always with a human focus, whether that’s on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential. At UCB, we’ve embraced a hybrid-first approach to work, bringing teams together in local hubs to foster collaborative curiosity. Unless expressly stated in the description or precluded by the nature of the position, roles are hybrid with 40% of your time spent in the office.
UCB is an equal opportunity employer. All employment decisions will be made without regard to any characteristic protected by applicable laws. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on EMEA-Reasonable_Accommodation@ucb.com. Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.
Principal Scientist PK/PD in Princes Risborough employer: Ucb Group
UCB is an exceptional employer that prioritises innovation and collaboration, making a significant impact in the biopharmaceutical industry. With a supportive work culture that values inclusivity and personal growth, employees are encouraged to pursue their career aspirations while contributing to meaningful advancements in patient care. Located in Slough, UK, with plans to transition to Windlesham, Surrey, UCB offers a hybrid work model that fosters teamwork and flexibility, ensuring a balanced and rewarding work environment.
StudySmarter Expert Advice🤫
We think this is how you could land Principal Scientist PK/PD in Princes Risborough
✨Unlock Networking Opportunities
Dive into industry-specific events like pharmaceutical conferences and seminars, where you can meet hiring managers from companies like Ucb Group. These are goldmines for making connections and learning about job openings before they hit the mainstream job boards.
✨Join Relevant Professional Bodies
Get involved with organisations such as the Royal Pharmaceutical Society or your local pharmaceutical professionals' network. Being an active member can boost your credibility and may even lead to job referrals in top organisations like Ucb Group.
✨Leverage Internships for Full-time Roles
If you can, consider pursuing internships in the pharmaceutical industry, especially with companies like Ucb Group. These opportunities often pave the way for full-time positions and allow you to demonstrate your capabilities firsthand.
✨Tailor Your Approach
When you're applying for roles, don't rush it! Take the time to customise your applications for specific positions, showcasing relevant skills and experiences that align with what Ucb Group is looking for. A tailored application can really make you stand out!
We think you need these skills to ace Principal Scientist PK/PD in Princes Risborough
Some tips for your application 🫡
Showcase Your Relevant Experience:When applying for a role in the pharmaceutical industry, it's crucial to highlight any relevant experience you have. Whether that's internships, lab work, or even related coursework, make sure to weave this into your CV and cover letter. We want to see how your background aligns with the role you're applying for at Ucb Group!
Emphasise Your Understanding of Regulations:The pharmaceutical industry is heavily regulated, so it's important to indicate your familiarity with industry standards and regulations. In your cover letter, mention any training or certifications you've received that are relevant, or discuss projects where you’ve navigated compliance. This will show Ucb Group that you're not just a fit for the job but also a safety-conscious candidate!
Tailor Your CV to Be Result-Driven:Craft your CV to highlight quantifiable achievements, especially if you have previous roles in pharmaceuticals or related fields. Use metrics to demonstrate your impact, such as improved processing times or successful project completions while working on trials. This analytical approach will resonate well with hiring managers at Ucb Group!
Convey Your Passion for the Industry:In your cover letter, express why you are passionate about working in the pharmaceutical sector. Whether it’s your desire to contribute to groundbreaking drug research or improve patient outcomes, let it shine through! At Ucb Group, we value candidates who are truly enthusiastic about their work—you might just stand out from the crowd.
How to prepare for a job interview at Ucb Group
✨Understand the Science
Make sure you brush up on key pharmaceutical concepts and recent developments in the industry. You might get asked some technical questions during the interview at Ucb Group that show your grasp of drug development processes or regulatory requirements, so be ready to discuss them clearly.
✨Showcase Relevant Experience
If you have any hands-on experience or internships in a laboratory setting, be sure to highlight these in your responses. Think about the projects you worked on, the methodologies you used, and the impact you made. It's all about telling a story that connects your background to the role you're applying for.
✨Know Their Products
Take some time to familiarise yourself with Ucb Group’s product range and recent breakthroughs. Understanding their portfolio not only shows your enthusiasm for the role but also allows you to ask insightful questions that demonstrate your interest in actively contributing to their projects.
✨Be Ready for Regulatory Scenarios
In a full-time pharmaceutical role, understanding the regulatory landscape is crucial. Prepare for situational questions that may test your problem-solving skills concerning compliance and safety standards. You could be asked how you'd handle a hypothetical issue regarding a drug’s market release, so think through your approach.
