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- Tasks: Lead synthetic chemistry projects and collaborate with multidisciplinary teams to drive drug discovery.
- Company: Join an innovative biotech company at the forefront of drug discovery.
- Benefits: Competitive salary, dynamic work environment, and opportunities for professional growth.
- Other info: Work closely with top universities and contribute to groundbreaking research.
- Why this job: Make a real impact in drug discovery using cutting-edge technology and methodologies.
- Qualifications: PhD in Organic Chemistry or relevant experience, with strong skills in medicinal chemistry.
The predicted salary is between 70000 - 90000 £ per year.
The Company Transition Bio is an innovative, early-stage biotechnology company with the vision of being the world leader in drug discovery targeting biological condensates. At Transition Bio, multidisciplinary teams with diverse skillsets in biology, biophysics, chemistry, engineering, and machine learning work closely together, building first-in-class technology for high-throughput screening to aid hit identification and driving drug discovery.
We are seeking an outstanding and highly motivated medicinal chemist to join our research group at Transition Bio, where we are discovering & developing drugs that modulate biomolecular condensates. Our drug discovery engine (CONDENSOMICSâ„¢) is built on droplet microfluidics & machine learning, as we believe having the right tools is key to unlocking an exciting new field.
As a critical part of the internal drug discovery team and working closely with external providers of chemistry and ADME services, this individual will contribute to discovery programs across multiple indications, from target discovery & validation through hit-to-lead and lead optimization activities. The successful candidate will have strong interpersonal skills and leadership qualities, will have demonstrated a successful track-record working with CROs and contributing to delivering projects against challenging targets, and enjoy working in a truly multi-disciplinary environment.
This position will report directly to our head of chemistry, and interact closely with Transition Bio colleagues in chemistry, data sciences, biology, and protein sciences, as well as external partners and consultants.
Key Responsibilities- Lead synthetic chemistry efforts across projects towards milestone achievements through expertise in synthetic chemistry and excellent communication and organisational skills.
- Manage outsourced chemistry, establishing and maintaining positive working relationships with internal team and external providers.
- Organise information sharing and sample distribution across various sites, continuously improving efficiency of existing workflows.
- Work closely and collaboratively with other disciplines and stakeholders (biology, DMPK, toxicology, etc.) in broader drug discovery to help drive programs forward.
- Represent Synthetic Chemistry as well as contribute to drug design across all Transition Bio discovery projects.
- Support and possibly lead publication efforts to strengthen the company’s external scientific reputation, including patent write up and articles.
- PhD in Organic Chemistry, or substantial relevant work experience.
- Solid industry medicinal chemistry experience with a passion for synthesis.
- Recognised expertise in synthetic chemistry and drug discovery process.
- Experience working with international CROs, vendors and other external partners through various phases of drug discovery.
- Excellent communication and presentation skills, capable of leading complex scientific discussions with partners and reporting back to key stakeholders.
- Experience working on diverse range of challenging chemistry, prior exposure to CMC desirable.
- Solid understanding of medicinal chemistry principles applied to drug design, including physiochemical and ADME.
- Critical but respectful thinking, desire to improve ways of working by bringing and implementing their own ideas.
- Evidence of working collaboratively with key related disciplines (Drug Design, DMPK, cell biology, safety, formulation, etc.).
- Familiarity with tools used in drug design.
Associate Director, Synthetic Chemistry in Cambridge employer: Transition Bio
Contact Detail:
Transition Bio Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Associate Director, Synthetic Chemistry in Cambridge
✨Tip Number 1
Network like a pro! Reach out to your connections in the biotech field, especially those linked to Transition Bio. A friendly chat can sometimes lead to opportunities that aren’t even advertised.
✨Tip Number 2
Prepare for interviews by diving deep into Transition Bio’s projects and technologies. Show us you’re not just interested in the role but also passionate about our mission in drug discovery.
✨Tip Number 3
Don’t underestimate the power of follow-ups! After an interview, drop us a quick thank-you email. It shows your enthusiasm and keeps you fresh in our minds.
✨Tip Number 4
Apply through our website! It’s the best way to ensure your application gets seen by the right people. Plus, it shows you’re keen on being part of our innovative team at Transition Bio.
We think you need these skills to ace Associate Director, Synthetic Chemistry in Cambridge
Some tips for your application 🫡
Show Your Passion for Chemistry: When writing your application, let your enthusiasm for synthetic chemistry shine through. We want to see how your passion aligns with our mission at Transition Bio and how you can contribute to our innovative drug discovery efforts.
Tailor Your Experience: Make sure to highlight your relevant experience in medicinal chemistry and working with CROs. We’re looking for candidates who can demonstrate a solid track record, so be specific about your achievements and how they relate to the role.
Communicate Clearly: Your written application should reflect your excellent communication skills. Use clear and concise language to convey your ideas, and don’t forget to showcase your ability to lead complex scientific discussions, as this is key for us at Transition Bio.
Apply Through Our Website: We encourage you to apply directly through our website. This not only streamlines the process but also ensures that your application gets the attention it deserves. Plus, it’s a great way to show your interest in being part of our team!
How to prepare for a job interview at Transition Bio
✨Know Your Chemistry Inside Out
Make sure you brush up on your synthetic chemistry knowledge and be ready to discuss specific methodologies you've used in past projects. Transition Bio is looking for someone with a solid understanding of drug discovery processes, so be prepared to explain how your expertise aligns with their CONDENSOMICSâ„¢ approach.
✨Showcase Your Collaborative Spirit
Since this role involves working closely with multidisciplinary teams, highlight your experience collaborating with other disciplines like biology and data sciences. Share examples of how you've successfully managed relationships with CROs and external partners to drive projects forward.
✨Prepare for Complex Discussions
Expect to engage in detailed scientific discussions during the interview. Practice articulating your thoughts clearly and confidently, especially when it comes to presenting your ideas on drug design and synthesis. This will demonstrate your excellent communication skills, which are crucial for this position.
✨Bring Ideas for Improvement
Transition Bio values critical thinking and innovation. Think about ways you could improve existing workflows or introduce new methodologies in synthetic chemistry. Be ready to share these ideas during your interview to show that you're proactive and eager to contribute to the team's success.