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- Tasks: Lead drug discovery projects and collaborate with multidisciplinary teams to develop innovative therapies.
- Company: Join Transition Bio, a pioneering biotech firm at the forefront of drug discovery.
- Benefits: Competitive salary, dynamic work environment, and opportunities for professional growth.
- Other info: Work closely with top universities and contribute to groundbreaking scientific advancements.
- Why this job: Make a real impact in drug discovery using cutting-edge technology and methodologies.
- Qualifications: PhD in relevant field and extensive medicinal chemistry experience required.
The predicted salary is between 80000 - 120000 ÂŁ per year.
The Company Transition Bio is an innovative, earlyâstage biotechnology company with the vision of being the world leader in drug discovery targeting biological condensates. At Transition Bio, multidisciplinary teams with diverse skillsets in biology, biophysics, chemistry, engineering, and machine learning work closely together, building firstâinâclass technology for highâthroughput screening to aid hit identification and driving drug discovery.
We are seeking an outstanding and highly motivated medicinal chemist to join our scientific team at Transition Bio, where we are discovering and developing drugs that modulate biomolecular condensates. Our drug discovery engine (CONDENSOMICSTM) is built on droplet microfluidics and machine learning, as we believe having the right tools is key to unlocking an exciting new field.
As a critical part of the internal drug discovery team and working closely with external providers of chemistry and ADME services, this individual will impact discovery programs across multiple indications, from target discovery and validation through hitâtoâlead and lead optimization activities. The successful candidate will have strong interpersonal skills and leadership qualities, will have demonstrated leadership in delivering projects against challenging targets, and enjoy working in a truly multiâdisciplinary environment. This position will report directly to our head of chemistry, and interact closely with Transition Bio colleagues in chemistry, data sciences, biology, and protein sciences, as well as external providers of chemistry and ADME services.
Key Responsibilities- Lead drug discovery project teams towards milestone achievements through expertise in small molecule medicinal chemistry across a broad range of targets.
- Manage resources, maintaining positive working relationships with internal team and external providers.
- Work closely and collaboratively with other disciplines (biology, DMPK, toxicology, etc.) and stakeholders in broader drug discovery to drive the programs forward.
- Secure intellectual property while driving medicinal chemistry efforts.
- Strongly contribute to drug design across all Transition Bio discovery projects, as well as continuous improvement of our workflows.
- Support target discovery and validation with medicinal chemistry perspectives.
- Contribute to establishing external scientific reputation by authoring key publications.
- PhD in Organic Chemistry, Chemical Biology, Medicinal Chemistry, or substantial relevant work experience.
- Extensive industry medicinal chemistry experience.
- Deep understanding of drug discovery process and a track record of contributing to project progression into LG, LO and DC nomination.
- Expertise in medicinal chemistry principles applied to drug design, including the optimisation of physiochemical and ADMET properties suitable for candidate nomination.
- Experience in working with external teams of chemists (CROs).
- Excellent communication and presentation skills, capable of conveying complex scientific information in a clear and scientific manner.
- Critical but respectful thinking, contribute to people's development and company culture.
- Experience of informatics tools for data upload, retrieval, analysis and visualisation.
- Experience working on diverse range of challenging targets and therapeutics areas; in particular, oncology/neurological disorders.
- Experience and/or knowledge of key related disciplines (DMPK, cell biology, safety, formulation, etc.).
- Familiarity with tools for virtual screening and machine-learning/AI-enabled drug design.
Associate Director / Director, Medicinal Chemistry in Cambridge employer: Transition Bio
Contact Detail:
Transition Bio Recruiting Team
StudySmarter Expert Advice đ¤Ť
We think this is how you could land Associate Director / Director, Medicinal Chemistry in Cambridge
â¨Tip Number 1
Network like a pro! Reach out to your connections in the biotech field, especially those at Transition Bio or similar companies. Attend industry events and engage in conversations that could lead to opportunities.
â¨Tip Number 2
Show off your skills! Prepare a portfolio showcasing your past projects and achievements in medicinal chemistry. This will help you stand out during interviews and demonstrate your expertise.
â¨Tip Number 3
Be proactive! Donât just wait for job openings to appear. Reach out directly to Transition Bio and express your interest in their work. A personal touch can make a big difference.
â¨Tip Number 4
Stay updated on industry trends! Follow the latest research and advancements in drug discovery and machine learning. This knowledge will not only impress interviewers but also show your passion for the field.
We think you need these skills to ace Associate Director / Director, Medicinal Chemistry in Cambridge
Some tips for your application đŤĄ
Show Your Passion for Medicinal Chemistry: When writing your application, let your enthusiasm for medicinal chemistry shine through! We want to see how your background and experiences align with our innovative approach at Transition Bio. Share specific examples of projects you've worked on that demonstrate your expertise and passion.
Tailor Your CV and Cover Letter: Make sure to customise your CV and cover letter for the role. Highlight relevant experiences that match the job description, especially your work with CROs and drug discovery processes. This shows us that you understand what weâre looking for and how you can contribute to our team.
Be Clear and Concise: Keep your application clear and to the point. Use straightforward language to convey your skills and experiences. We appreciate well-structured applications that make it easy for us to see your qualifications without sifting through unnecessary details.
Apply Through Our Website: Donât forget to apply through our website! Itâs the best way for us to receive your application and ensures youâre considered for the role. Plus, it gives you a chance to explore more about our company and culture while youâre at it!
How to prepare for a job interview at Transition Bio
â¨Know Your Chemistry Inside Out
Make sure you brush up on your medicinal chemistry knowledge, especially around drug design and the optimisation of ADMET properties. Be ready to discuss specific projects you've worked on and how they relate to the role at Transition Bio.
â¨Showcase Your Leadership Skills
Transition Bio is looking for someone with strong interpersonal skills and leadership qualities. Prepare examples of how you've led project teams in the past, particularly in challenging environments, and how you managed resources effectively.
â¨Collaborate Like a Pro
Since this role involves working closely with multidisciplinary teams, be prepared to discuss your experience collaborating with other disciplines like biology and DMPK. Highlight any successful partnerships you've had with external providers or CROs.
â¨Communicate Clearly and Confidently
Youâll need to convey complex scientific information clearly. Practice explaining your past work in a straightforward manner, focusing on how your contributions have driven drug discovery projects forward. This will show your ability to communicate effectively within a team.