Senior Scientist - Molecular Diagnostics (Production) in Cambridge

Senior Scientist - Molecular Diagnostics (Production) in Cambridge

Cambridge Full-Time 40000 - 50000 £ / year (est.) No working from home possible
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At a Glance

  • Tasks: Lead molecular diagnostics projects and optimise laboratory processes for cancer detection.
  • Company: Join The Origin Group, a leader in medical technology and innovation.
  • Benefits: Enjoy 25 days holiday, pension contributions, and a competitive salary.
  • Other info: Collaborative environment with opportunities for scientific communication and career growth.
  • Why this job: Make a real impact in cancer diagnostics and improve patient outcomes.
  • Qualifications: MSc/PhD in relevant fields and experience in NGS and assay development.

The predicted salary is between 40000 - 50000 £ per year.

  • Description
  • Our Company

The Origin Group Limited (TOGL (Holdings) Ltd) is the parent organisation and technical service provider to a focused portfolio of UK-based medical technology, research, and innovation companies.

Organisations within the group include Origin Sciences, Ellele Health and Biomii.

Origin Sciences is a clinical-stage diagnostics company developing and commercialising novel medical devices for gastrointestinal diseases.

Our proprietary sample collection technology underpins innovative diagnostic solutions across multiple diagnostic areas with a focus on colorectal cancer.

Currently, our diagnostic development programs primary focus is the detection of Colorectal Cancer (CRC) and pre-cancerous lesions.

Our motivation is to streamline the colorectal cancer detection pathway, enabling healthcare systems to focus on those patients with serious pathologies, ultimately reducing waiting times, enabling earlier detection, and minimising unnecessary investigations performed on healthy patients.

The Role

The Senior Scientist is an experienced laboratory scientist in the field of life sciences, with a proven track record in molecular diagnostics, biomarker validation, PCR-based assays, NGS technologies and cancer genetics.

The Senior Scientist will support and lead laboratory processes, with a particular focus on molecular biology and Next Generation Sequencing (NGS), as such a proven track record of PCR and NGS is essential.

An honours degree in biological sciences, biomedical sciences, biochemistry or equivalent is required in addition to practical knowledge of biomarker validation, assay optimisation and working with clinical samples.

Education to MSc/Ph D level would be preferred, but extensive relevant laboratory experience is also acceptable for the role.

This position is part of the Production Team working to deliver a molecular diagnostics assay with associated NGS technologies.

The Senior Scientist will work to operate, optimise and maintain validated laboratory processes, and to support the transfer and verification of new and updated methods into routine use.

This position requires high attention to detail, the ability to critically assess data, to work to SOPs and a strong focus on quality and reproducibility.

Skilled project and time management and the capacity to work well individually or as part of a team are essential.

Additionally, the Senior Scientist may contribute to the assessment of new technologies and providers, and to the preparation of appropriate documentation for notified body submission.

The specific duties of a Senior Scientist are

  • Perform nucleic acid extraction and store biobank clinical samples.
  • Support the implementation and verification of new and updated detection workflows.
  • Liaise with the clinical trial teams to coordinate clinical sample deliveries.
  • Complete stability, performance, and validation assays, followed by analysis and reporting.
  • Execute and maintain established assays for routine sample testing.
  • Work towards the goals of collaborative projects with external partners.
  • Be accountable for the time, cost, and quality of agreed deliverables.
  • Provide updates on the progress, risks, and opportunities of the agreed deliverables.
  • Work within a regulated environment in accordance with ISO 13485 and ISO 15189
  • Assess related diagnostic technologies and products.
  • Contribute to scientific communication and documentation, including peer-reviewed publications, leaflets and posters, as required.
  • Support the day-to-day management of laboratory pipelines and workflows, including sample tracking, scheduling, and throughput monitoring, to ensure the timely and reproducible delivery of results.
  • To ensure projects are carried out in accordance with Origin's Quality Systems and Regulatory Standards.

Requirements

Essential Knowledge, Skills and Experience

  • Enthusiastic and self-motivated individual.
  • MSc/Ph D in Genetics, Epigenetics, Cancer Biology, Molecular Biology or Biochemistry.
  • Greater than 3 years of scientific research experience in next-generation sequencing and assay development.
  • Excellent understanding of molecular biology techniques.
  • Excellent attention to detail and record keeping.
  • Ability to critically evaluate data, focusing on quality and reproducibility.
  • Proficiency in time management, multitasking, and the ability to collaborate with a multidisciplinary team.
  • Good organisational skills.
  • Strong interpersonal communication skills.

Desirable Knowledge, Skills and Experience

  • Knowledge of epigenetics assays development.
  • Experience working with clinical samples.
  • Experience working in a regulated environment, e. g. Good Clinical Practice, ISO 13485 or other Gx P.

Benefits

  • 25 days holidays
  • Pension contribution
  • Competitive Salary

Senior Scientist - Molecular Diagnostics (Production) in Cambridge employer: TOGL

The Origin Group Limited is an exceptional employer, offering a dynamic work environment that fosters innovation in the medical technology sector. With a strong focus on employee growth and development, team members benefit from collaborative projects and the opportunity to contribute to groundbreaking diagnostic solutions. Located in the UK, the company provides competitive salaries, generous holiday allowances, and a supportive culture that prioritises quality and excellence in healthcare.

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Contact Details:

TOGL Recruitment Team

StudySmarter Expert Advice🤫

We think this is how you could land Senior Scientist - Molecular Diagnostics (Production) in Cambridge

Get Involved in Local Research Communities

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We think you need these skills to ace Senior Scientist - Molecular Diagnostics (Production) in Cambridge

Molecular Diagnostics
Biomarker Validation
PCR-based Assays
Next Generation Sequencing (NGS)
Cancer Genetics
Assay Optimisation
Nucleic Acid Extraction

Some tips for your application 🫡

Show Off Your Lab Skills:In the biotechnology field, it's super important to highlight your lab experience in your CV. Be sure to mention specific techniques or instruments you've mastered (think PCR, gel electrophoresis, etc.) and any relevant projects you've worked on. This will show TOGL that you have the hands-on skills they need.

Tailor Your Technical Skills:Make sure to emphasise your technical skills, especially those relevant to the biotechnology sector. Include any software tools or programming languages you've used, like R or Python for data analysis, which could be key for this role at TOGL.

Craft a Compelling Cover Letter:Since this is a full-time role, your cover letter should reflect not only your passion for biotechnology but also your long-term career ambitions. Share why you're excited about the work that TOGL does and how you envision contributing to their goals. This shows that you’re not just looking for any job, but you're genuinely invested in this opportunity.

Include Your Papers and Projects:If you've published any papers or contributed to significant projects, mention them! These documents can boost your application and provide tangible evidence of your expertise in the biotechnology field. Don’t forget to link to any relevant publications or project summaries—this can set you apart from other candidates.

How to prepare for a job interview at TOGL

Brush Up on Lab Techniques

Since you're eyeing a full-time gig in biotechnology, make sure you're well-versed in the lab techniques relevant to the role. Be ready to talk about PCR, CRISPR, or any specific methods mentioned in the job description at TOGL. You might even be asked to demonstrate your understanding of these processes.

Know Your Bioinformatics Tools

Get comfortable with bioinformatics tools that are commonly used in the industry, like BLAST or Bioconductor. These are key in biotechnology, and having hands-on experience or at least familiarity can set you apart. Prepare to discuss any relevant projects you've worked on, especially if they involved data analysis or genomic research.

Show Your Teamwork Skills

Biotech often involves collaboration across multiple disciplines. Be ready to share stories that highlight your teamwork and communication skills, especially in research projects. Think about working with different teams at university or any internships – this is where you can show how well you fit into TOGL's culture.

Research Recent Biotech Innovations

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