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- Tasks: Lead CHO cell line projects and optimise cell lines using advanced techniques.
- Company: Join TieTalent, a dynamic biopharma team in Oxford shaping the future of biologics.
- Benefits: Enjoy competitive salary, generous holidays, pension scheme, and ongoing training.
- Why this job: Be part of innovative projects that impact biotherapeutic production and collaborate with experts.
- Qualifications: PhD or MSc in relevant fields with 5+ years in CHO cell line development required.
- Other info: This is a full-time, permanent role based in Oxford.
The predicted salary is between 36000 - 60000 £ per year.
Join to apply for the Cell Line Development Scientist role at TieTalent
Join to apply for the Cell Line Development Scientist role at TieTalent
About
We’re hiring a skilled Cell Line Development Scientist to join a fast-paced biopharma team in Oxford. This full-time, permanent role offers the chance to lead CHO cell line projects supporting early-stage biologics manufacturing. You’ll play a key part in engineering and optimizing cell lines using cutting-edge techniques like CRISPR/Cas9 and miniature bioreactors (ambr15), contributing from design through to early clinical production.
About
We’re hiring a skilled Cell Line Development Scientist to join a fast-paced biopharma team in Oxford. This full-time, permanent role offers the chance to lead CHO cell line projects supporting early-stage biologics manufacturing. You’ll play a key part in engineering and optimizing cell lines using cutting-edge techniques like CRISPR/Cas9 and miniature bioreactors (ambr15), contributing from design through to early clinical production.
About The Role
As a Scientist in the Cell Line Development group, you’ll drive projects focused on CHO cell engineering, stability assessment, and clone selection. You’ll collaborate with analytical and process development teams, manage key experiments, and help shape the future of biotherapeutic production.
Key Responsibilities
Develop and characterize CHO cell lines for biologic production.
Design gene editing strategies (e.g., CRISPR/Cas9) to enhance cell performance.
Conduct transfections, single cell cloning, and clone screening.
Run stability studies and guide Cell Bank generation.
Operate miniature (ambr15) and small-scale bioreactors for process evaluation.
Accurately analyze and report experimental data.
Collaborate across functions to meet project goals.
Ensure biosafety and quality compliance.
About You
PhD or MSc in Cell Biology, Biotechnology, Biochemical Engineering or related field.
5+ years of hands-on experience in CHO cell line development (biopharma or CDMO preferred).
Strong skills in CHO cultivation, gene editing, and bioreactor operation.
Experience with CRISPR/Cas9, transfection, and clone selection workflows.
Familiarity with regulatory-compliant stability testing and Cell Bank generation.
Proficiency in data analysis, electronic lab notebooks, and biopharma software tools.
Strong communication and organizational skills; leadership experience is a plus.
Salary & Benefits
Competitive salary with bonus
Generous holiday allowance and pension scheme
Comprehensive benefits package
Ongoing training and development
Based in Oxford
Ready to Apply?
If you bring the experience and enthusiasm to make an impact in this role, we’d love to hear from you. Apply now to be part of a growing and innovative team shaping the future of biotherapeutics
Nice-to-have skills
- Data Analysis
- Oxford, England, United Kingdom
Languages
- English
Seniority level
-
Seniority level
Mid-Senior level
Employment type
-
Employment type
Full-time
Job function
-
Job function
Research, Analyst, and Information Technology
-
Industries
Technology, Information and Internet
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Cell Line Development Scientist employer: TieTalent
Contact Detail:
TieTalent Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Cell Line Development Scientist
✨Tip Number 1
Familiarise yourself with the latest techniques in cell line development, especially CRISPR/Cas9 and miniature bioreactors like ambr15. Being able to discuss these technologies confidently during your interview will show that you're up-to-date and passionate about the field.
✨Tip Number 2
Network with professionals in the biopharma industry, particularly those who have experience in CHO cell line development. Attend relevant conferences or webinars, and don’t hesitate to reach out on platforms like LinkedIn to connect with potential colleagues at TieTalent.
✨Tip Number 3
Prepare to showcase your hands-on experience by discussing specific projects where you engineered or optimised cell lines. Highlight any challenges you faced and how you overcame them, as this demonstrates problem-solving skills and resilience.
✨Tip Number 4
Brush up on your data analysis skills, as proficiency in analysing experimental data is crucial for this role. Be ready to talk about the software tools you’ve used and how they contributed to your research outcomes.
We think you need these skills to ace Cell Line Development Scientist
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights relevant experience in CHO cell line development, gene editing techniques like CRISPR/Cas9, and any hands-on work with bioreactors. Use specific examples to demonstrate your skills.
Craft a Compelling Cover Letter: In your cover letter, express your enthusiasm for the role and the company. Mention how your background aligns with the responsibilities listed, such as developing and characterising CHO cell lines and collaborating across functions.
Highlight Key Skills: Emphasise your strong skills in data analysis, biosafety compliance, and project management. Make sure to mention any leadership experience, as it’s a plus for this role.
Proofread Your Application: Before submitting, carefully proofread your application for any spelling or grammatical errors. A polished application reflects your attention to detail, which is crucial in scientific roles.
How to prepare for a job interview at TieTalent
✨Showcase Your Technical Skills
Make sure to highlight your hands-on experience with CHO cell line development, CRISPR/Cas9 techniques, and bioreactor operation. Be prepared to discuss specific projects where you successfully applied these skills.
✨Prepare for Scenario-Based Questions
Expect questions that assess your problem-solving abilities in real-world scenarios. Think of examples where you had to design gene editing strategies or conduct stability studies, and be ready to explain your thought process.
✨Demonstrate Collaboration Experience
Since the role involves working with various teams, share examples of how you've effectively collaborated with analytical and process development teams in the past. Highlight any leadership roles you've taken on during these collaborations.
✨Understand Regulatory Compliance
Familiarise yourself with the regulatory aspects of cell line development and stability testing. Be ready to discuss how you ensure biosafety and quality compliance in your work, as this is crucial for the role.
