At a Glance
- Tasks: Lead and manage multi-centre cancer clinical trials, ensuring compliance and quality assurance.
- Company: Sheffield Clinical Trials Research Unit, a leader in oncology research.
- Benefits: Generous annual leave, competitive salary, and opportunities for professional growth.
- Other info: Join a supportive team with a focus on innovation and impactful research.
- Why this job: Make a real difference in cancer research while advancing your career in a dynamic environment.
- Qualifications: Postgraduate qualification and experience in managing large oncology clinical trials.
The predicted salary is between 48822 - 65509 £ per year.
Salary Grade 8 £48,822-£65,509
Overview: Senior Trial Manager, equivalent to Senior Research Fellow (Grade 9) or Research Fellow (Grade 8), based in the Sheffield Clinical Trials Research Unit (CTRU). Sheffield CTRU has received substantial infrastructure funding to grow and diversify its portfolio of multi-centre cancer clinical trials. The post holder will be responsible for trial design, grant development, and submission, as well as oversight of Quality Assurance and senior-level study implementation, with a specific focus on oncology-based CTIMPs (Clinical Trials of Investigational Medicinal Products) as part of the Sheffield Oncology Clinical Trials Infrastructure Programme (SOCTIP). You will work closely with the CTRU Academic Lead for Oncology, CTRU staff and Chief Investigators to secure research funding and ensure that studies under your supervision are implemented in accordance with randomised controlled trial scientific principles, the study protocols, and regulatory standards. You will provide oversight of all CTRU input into the specialist oncology studies within your portfolio, ensuring that all services provided by the Unit are compliant with professional, national, and international regulatory frameworks. Whilst the post is funded fixed term until March 2031, if successful it is envisaged that the position will be income‑generating and so funded on an ongoing basis beyond this.
Main Duties And Responsibilities:
- Portfolio Management: Support the CTRU Director and Academic Lead for Oncology in the strategic delivery of the Sheffield Oncology Clinical Trials Infrastructure Programme (SOCTIP).
- Trial Delivery: Responsible for overseeing the set-up, coordination, and delivery of large multi-site clinical trials, including protocol development, obtaining regulatory approvals (IRAS/MHRA), and site initiation.
- Leadership (G9): Lead the development of a specialist oncology research portfolio, taking a primary role in designing studies and securing large research grants.
- Support & Advice (G8): Provide expert advice and support to researchers developing new funding proposals, specifically regarding trial design, resource costing, drug procurement and project management timelines.
- Regulatory & Quality Assurance: Oversee Quality Assurance processes and ensure compliance with the Medicines for Human Use (Clinical Trials) Regulations 2004, GCP, and data protection requirements.
- Staff Supervision: Supervise Trial Managers and study‑specific staff, providing mentorship and guidance on trial implementation.
- Research Output (G9): Lead the preparation of papers for high‑impact oncology and academic journals and present findings at international conferences.
- Research Output (G8): Contribute to academic papers and disseminate research findings through reports and publications.
Qualifications & Experience:
- Postgraduate qualification in a relevant health‑related or methodological area.
- Experience in trial set‑up and delivery for large, multi‑centre CTIMPs.
- Proven track record of managing large, multi‑centre oncology CTIMPs from set‑up to close‑out.
- Research experience within the oncology field.
- Extensive experience and deep understanding of cancer‑specific trial complexities.
- Experience coordinating Clinical Trials of Investigational Medicinal Products (CTIMPs).
- Experience working on complex Oncology CTIMPs and oncology pharmacovigilance.
- Experience supporting the writing of grant applications and coordinating expertise for proposals.
- Proven track record of successfully securing major research grants (e.g., NIHR, CRUK, MRC).
- Strong track record of high‑quality, peer‑reviewed research papers in high‑impact oncology journals.
- Experience supervising/coordinating study staff and motivating a team.
Benefits: Minimum of 41 days annual leave including
Contact Details:
The University of Sheffield Recruitment Team
