At a Glance
- Tasks: Join our team to produce cutting-edge gene therapies in a dynamic cleanroom environment.
- Company: The University of Sheffield, a world-class institution dedicated to innovation and diversity.
- Benefits: Enjoy 38+ days of annual leave, flexible working, and a generous pension scheme.
- Other info: Be part of a supportive community that values diverse backgrounds and personal development.
- Why this job: Make a real impact on patients' lives while advancing your career in biotechnology.
- Qualifications: BSc in a scientific field and experience in gene therapy or biotechnology preferred.
The predicted salary is between 27319 - 27319 £ per year.
The University of Sheffield is a remarkable place to work. Our people are at the heart of everything we do. Their diverse backgrounds, abilities and beliefs make Sheffield a world-class university. We offer a fantastic range of benefits including a highly competitive annual leave entitlement, a generous pension scheme, flexible working opportunities, a commitment to your development and wellbeing, a wide range of retail discounts, and much more.
Overview
Reporting to the Head of Manufacturing, the Manufacturing Technician is a core part of Manufacturing operations at the Gene Therapy Innovation and Manufacturing Centre (GTIMC), performing routine manufacturing of medicines for Gene Therapies and rare diseases. The manufacturing team acts as a CDMO for academic clients. The Manufacturing Technician will support the day to day running of the GMP cleanroom facility including cleaning, environmental monitoring, material transfer.
Main Duties and Responsibilities
- Perform routine manufacturing processes using aseptic techniques to produce GMP batches for clinical applications of Gene Therapies.
- Support all technical, logistical and housekeeping aspects of GMP vector production and clean room operation at the GTIMC.
- Maintain quality production documentation within the GTIMC Quality Management System to GMP standards.
- Maintain and calibrate equipment and instruments within the manufacturing clean rooms.
- Contribute to the development, writing and implementation of standard operating procedures for the GTIMC.
- Maintain the operational cleanliness of the clean rooms in line with GMP and GTIMC housekeeping procedures.
- Work as part of the wider GTIMC team, providing support as required to the other teams across the GTIMC facility.
- Carry out investigations and root cause analysis of manufacturing exceptions and non-conformances.
- Support the continued improvement of GTIMC AAV production via implementation of process developments.
- Participate in Technology Transfer activities within the GTIMC Quality Management System to GMP standards.
- Carry out other duties, commensurate with the grade and remit of the post.
Person Specification
Our diverse community of staff and students recognises the unique abilities, backgrounds, and beliefs of all. We foster a culture where everyone feels they belong and is respected. Even if your past experience doesn't match perfectly with this role's criteria, your contribution is valuable, and we encourage you to apply.
- BSc (or equivalent) in a scientific field - Essential
- Relevant work experience in manufacturing capacity within gene therapy, biotechnology or other biological sciences - Essential
- Experience with aseptic practices - Essential
- Working knowledge of GMP and the ability to apply standards as required for compliance - Essential
- Attention to detail and a proven ability to keep accurate and reliable records - Essential
- Good interpersonal, verbal and written communication skills - Essential
- Comfortable in a fast-paced operational environment with minimal supervision - Essential
- Ability to work independently as well as part of a multidisciplinary team - Essential
- Good organisational and time management skills - Essential
- Experience of processing production techniques for AAV or Lenti vector systems - Desirable
- Report Writing Skills and Experience of Delivering Presentations - Desirable
- Experience working within a Quality Management System (QMS) - Desirable
Further Information
Grade: 5
Salary: £27,319
Work arrangement: Full-time
Duration: 3 years Fixed Term
Line manager: Toby Gamlen
Direct reports: Manufacturing Lead, Manufacturing technician
Right to work in the UK: This role does not meet the criteria for Skilled Worker sponsorship under the UK Visa & Immigration points-based system.
Contact For informal enquiries about this job contact Toby Gamlen, Head of Manufacturing: on t.gamlen@sheffield.ac.uk or on 0114 2220652.
Next steps in the recruitment process It is anticipated that the selection process will take place w/c 21st September. This will consist of an interview, a test and a presentation.
What We Offer
- A minimum of 38 days annual leave including bank holiday and closure days (pro rata).
- Flexible working opportunities, including hybrid working for some roles.
- Generous pension scheme.
- A wide range of discounts and rewards on shopping, eating out and travel.
- A variety of staff networks, providing opportunities for social interaction, peer support and personal development.
- Recognition Awards to reward staff who go above and beyond in their role.
- A commitment to your development access to learning and mentoring schemes.
- A range of generous family-friendly policies.
Manufacturing Technician employer: The University of Sheffield
The University of Sheffield is an exceptional employer, offering a vibrant work culture that prioritises employee development and well-being. As a Senior Technician in the Geotechnical & Water Engineering Research Group, you will benefit from generous annual leave, flexible working arrangements, and a commitment to professional growth through mentoring and training opportunities. Located on a central campus, you'll be part of a diverse community that values innovation and collaboration, making it a rewarding place to contribute to meaningful research and education.
Contact Details:
The University of Sheffield Recruitment Team
StudySmarter Expert Advice🤫
We think this is how you could land Manufacturing Technician
✨Join Local Manufacturing Groups
Getting involved in local manufacturing groups or associations can seriously boost your visibility. These groups often have insider info on job openings and networking events, plus they help you connect with like-minded folks in the industry. Check out what's happening in your area!
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Consider participating in workshops or open days at manufacturing companies. It's a great way to show off your hands-on skills in a real-world environment and can sometimes lead to job offers right on the spot. Keep an eye on announcements from local manufacturers for these opportunities!
✨Leverage the Power of Internships
While you're looking for full-time positions, don't underestimate the power of internships! Even if you don't see a direct role, securing an internship at a company can open doors to future jobs. Many manufacturing firms prefer to hire from their intern pool, so it's definitely worth considering.
✨Apply Directly Through Company Websites
When you find a role at a company you love, like The University of Sheffield, apply directly on their website. This way, you’re more likely to be noticed by the hiring team. Plus, showing that you took the time to seek out their application process highlights your genuine interest in the firm!
We think you need these skills to ace Manufacturing Technician
Some tips for your application 🫡
Showcase Your Technical Skills:In the manufacturing-production sector, it's crucial to highlight your technical skills and experience. Make sure your CV features any relevant qualifications, such as certifications in machinery operation or production management, and don’t forget about any specific systems or software you’re familiar with. This can really set you apart!
Emphasise Teamwork and Communication:Working in manufacturing often means being part of a larger team. Highlight your experience in collaborative projects or environments where communication was key. Maybe you have experience with lean manufacturing principles? Talk about how you worked with your team to improve productivity and maintain quality.
Tailor Your Cover Letter to the Company:Don’t just recycle an old cover letter! Take the time to tailor your cover letter to The University of Sheffield specifically. Mention what excites you about their production processes or products, and how your previous experiences can contribute to their goals. We want to see your enthusiasm for the role!
Use Concrete Examples of Your Achievements:When detailing your work experience, include measurable achievements that can demonstrate your impact. Whether it’s improving efficiency by a certain percentage or successfully leading a project, these specifics can make a huge difference. Numbers speak volumes in the manufacturing world!
How to prepare for a job interview at The University of Sheffield
✨Know Your Manufacturing Processes
Before you walk into the interview with The University of Sheffield, brush up on the specific manufacturing processes relevant to the role. Understanding lean manufacturing principles or quality control techniques could give you a solid edge to discuss how you’d fit into their operations.
✨Technical Questions Are Key
Be prepared for technical questions around machinery, production scheduling, or materials handling. Make sure you can confidently explain how you've dealt with these in past experiences or internships. Knowing industry-specific software could also be a big plus!
✨Showcase Your Problem-Solving Skills
Manufacturing environments often focus on continuous improvement. Be ready to discuss specific instances where you’ve solved a production issue or implemented a process improvement. It’s all about demonstrating your analytical thinking and hands-on approach.
✨Align Your Values with Quality and Safety
In a full-time role, companies like The University of Sheffield value commitment to quality and safety. Be prepared to discuss how you prioritise these factors in your work. It’s about showing that you’re not just looking for a job, but that you genuinely care about contributing positively to their production environment.