We are seeking a motivated and collaborative individual to join our team as a post-doctoral research associate/fellow with cancer genomics research experience. This role offers an exciting opportunity to analyse genomic data and calculate prostate cancer polygenic risk scores for the GP-TEST-Pro study. This clinical study involves a multidisciplinary team of leading academics from the University of Manchester, Queen Mary University London, University College London, and the Institute for Cancer Research and the postholder will be working within a dynamic and inclusive environment.
You will be responsible for:
- Receiving, securely storing and managing genomic data in line with University, NHS and study governance requirements.
- Performing genotype and imputed-data quality control, including sample-level and variant-level checks, ancestry and population-structure assessment, allele harmonisation and preparation of analysis-ready datasets.
- Using appropriate genetic analysis tools, such as PLINK/PLINK2 and imputation server outputs, to clean, process and analyse genomic data.
- Calculating and validating a 451-SNV prostate cancer polygenic risk score, including harmonisation of variants, application of published effect sizes and assessment of score distribution.
- Evaluating additional genomic markers or PRS approaches relevant to clinically significant prostate cancer detection.
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Post-Doctoral Research Associate/Fellow in Cancer Genomics in Manchester employer: The University of Manchester
The University of Manchester is an excellent employer, offering a vibrant work culture that values diversity and inclusivity. As a Sport Centre Assistant, you'll enjoy flexible shifts while contributing to a dynamic environment that prioritises high-quality experiences for all users. With ample opportunities for personal and professional growth, working at our esteemed institution allows you to make a meaningful impact in the community.
Contact Details:
The University of Manchester Recruitment Team
