Postdoctoral Research Scientist

The Pirbright Institute delivers world-leading research to understand, predict, detect and respond to viral disease outbreaks. We study viruses of livestock that are endemic and exotic to the UK, including zoonotic viruses, by using the most advanced tools and technologies to understand host-pathogen interactions in animals and arthropod vectors. Our major strength in understanding the immune systems of livestock provides a platform to control current diseases and respond to emerging threats. This important research would not be possible without the proportionate use of animals, which are integral to the development of new disease control measures such as vaccines and diagnostics. We have an establishment-wide commitment to the 3Rs (replacement, reduction and refinement), high standards of animal welfare, a culture of care and openness.

Our Institute is made up of a dynamic and vibrant community of staff covering a diverse set of chosen fields, backgrounds and experience. We all play a crucial role in furthering the Institute’s aspirations, advancing the frontiers of science and knowledge through our excellent scientific research, knowledge sharing and contribution; with a real focus in improving the world in which we live. Our outlook is always balanced by our strong sense of purpose, values and behaviours and an unwavering commitment to a ‘one Institute’ approach.

About the Viral Oncogenesis Group

Applications are invited to join the Viral Oncogenesis group at Pirbright Institute and report to the Head of the group. Our research has focused on investigation of host/virus interactions to unravel the molecular mechanisms of tumour formation by avian oncogenic viruses using state-of-the‑art technologies. The purpose of this position is to recruit a Post‑doctoral Research Scientist with experience in using conventional homologous recombination and CRISPR/Cas9 editing technologies to develop herpesvirus vectored vaccine.
The successful candidate will be required to manage the research project, work independently and liaise with all members of the team, as well as other research groups. The position offers the opportunity to become a pivotal member of the team striving to bring innovation through high‑impact research. The postholder will also have the prospects of working with the Head of the Group in management duties and supervision of students.

All employees shall actively participate in the Institute‑wide quality assurance system in conjunction with the Institute’s Quality Manager. Employees are also expected to safeguard their own health and safety and security by following policies and all employees are responsible for the Health and Safety and security of staff under their management.

Main duties and responsibility

• The post‑holder will carry out research to meet the objectives outlined in the industry‑funded project to develop avian herpesvirus vectored vaccine using conventional homologous recombination and CRISPR/Cas9 editing technologies.
• Be responsible for driving the project, contributing to experimental design and data analysis.
• Deal with problems that may affect the achievement of research objectives and deadlines.
• Contributing to develop new models, techniques and methods.
• Contributing and helping to develop innovative research projects for securing additional funding.
• Generating high impact research publications based on the findings from the research projects.
• Prepare regular brief reports for collaborators and contribute to video conference and in person discussions with collaborators.
• Supporting senior colleagues to enhance the international impact of the Institute by participation in meetings, joint projects and other activities.
• Assisting in Laboratory management responsibilities (ordering, looking after equipment, maintenance, sample inventories) and animal experiments under the Project Licence managed by the group.
• Contributing towards the Knowledge exchange, business development and outreach programmes of the Institute.
• Participate in the operational and academic management activities.
• Interact with other members of the group as well as other groups on wider aspects of research innovations into the control of avian viral diseases.

This job description is only an outline of the tasks, responsibilities and outcomes required of the role. The jobholder will carry out any other duties as may be reasonably required by his/her line manager. The job description and personal specification may be reviewed on an ongoing basis in accordance with the changing needs of The Pirbright Institute.

Due to the nature of the work we do, all successful applicants will be required to go through a comprehensive screening process including reference and qualification checks, financial and security clearances.

Specific requirements

• PhD degree in virology, cell biology, another relevant field of biology or equivalent
• Strong fundamental understanding of herpesvirus virology
• Proven experience in specialized molecular virology techniques such as herpesvirus manipulation by CRISPR/Cas9 editing system and/or homologous recombination techniques
• Good track record of publications in a relevant field, commensurate with the level of experience
• Demonstrated hands‑on experience working on the application and use of herpesvirus mutagenesis techniques in research
• Experience in working with industry partners and track record of delivery milestones of industry‑funded projects
• Evidence in time management skills, and able to plan own work, and meeting objectives without day‑to‑day monitoring

What we offer

• Generous Group Personal Pension Scheme and life cover (subject to age and earnings)
• 25 days annual leave per annum, pro rata, plus public and privilege days
• Buy and sell annual leave
• Option to carry over up to two weeks annual leave
• Pirbright gym with subsidized membership
• Pirbright social club
• Pirbright Lifestyle Hub (employee discount site)