This senior technical post sits within the MHRA's Beyond ADMET: AI for Medicines Safety regulatory sandbox, a programme testing how artificial intelligence can change medicines development and safety work. The postholder gives specialist scientific leadership across the programme, judging emerging methods, datasets and evidence and keeping technical workstreams and deliverables on track. The role works alongside the Head, AI for Medicines Safety and covers AI, toxicology, pharmacology and regulatory science, with stakeholder engagement across industry, academia and government. Applications must go through the Civil Service Jobs site.
What the job involves
- Provide senior scientific and technical leadership for the Beyond ADMET sandbox programme, keeping activities robust and aligned with regulatory objectives
- Work with the Head, AI for Medicines Safety so the programme draws on complementary expertise
- Lead evaluation of emerging methodologies, technologies, datasets and evidence for AI-enabled medicines development, safety assessment and regulatory decisions
- Provide technical oversight of project activities, ensuring scientific rigour and quality
- Give expert input into the design, delivery and evaluation of sandbox activities and use cases
- Coordinate technical workstreams and integrate scientific, technical and regulatory activity
- Monitor technical deliverables and milestones, identifying risks, issues and dependencies and proposing mitigations
- Build relationships with technical experts across the MHRA, industry, academia, government and life sciences
- Represent the programme at meetings, workshops, conferences and stakeholder events
- Translate programme outputs into regulatory and scientific outcomes, and write reports, briefings and presentations
- Support AI-enabled regulatory science capability across the MHRA and contribute to future frameworks, guidance and policy
- Deputise for the Head, AI for Medicines Safety at meetings, workshops and stakeholder engagements
Qualifications
- Degree in a relevant scientific, technical or healthcare discipline, or equivalent experience
- Postgraduate qualification (MSc, PhD or equivalent experience) in a relevant field such as AI, computational biology, pharmacology, toxicology, data science, bioinformatics or pharmaceutical sciences
Experience
- Significant experience and recognised expertise in AI and machine learning, healthcare data science and computational modelling, preclinical assessment, toxicology and NAMs, or pharmacology and drug development
- Applying scientific expertise to complex regulatory, healthcare, research or industry challenges, evaluating evidence and turning findings into recommendations
- Working with multidisciplinary teams and engaging external stakeholders, including academia, industry and research organisations
- Preparing technical reports, scientific assessments, briefings, publications or regulatory submissions
- AI model development, validation or deployment in healthcare or life sciences, or ADMET prediction, computational toxicology, modelling and simulation or related disciplines
Skills & knowledge
- Recognised technical expertise in pharmacology, toxicology, drug development, safety science, NAMs or related disciplines, or in AI, machine learning, healthcare data science or related disciplines
- Critically evaluating scientific evidence, AI methodologies, model performance and validation approaches
- Strong analytical skills and interpreting complex scientific, technical and data-driven information
- Excellent written and verbal communication, including explaining highly technical concepts to diverse audiences
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Contact Details:
The Methodist Church in Britain Recruitment Team
