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- Tasks: Research and develop therapies targeting leukaemic stem cells in acute myeloid leukaemia.
- Company: Join the Institute of Cancer Research, a leading cancer research institute.
- Benefits: Competitive salary, pension, professional development, and access to state-of-the-art facilities.
- Why this job: Make a real impact in cancer research and collaborate with top experts in the field.
- Qualifications: PhD in relevant fields and significant experience in hypoxia and cancer research.
- Other info: Dynamic environment with a commitment to diversity and inclusion.
The predicted salary is between 28800 - 48000 £ per year.
Key Information
- Salary: Dependent on relevant Postdoctoral experience. Future progression is based on annual performance review.
- Duration of Contract: Fixed term for 3 years
- Hours per week: 35 hours per week (Full Time)
- Location: Sutton
- Closing Date: 2nd March 2026
- This role is eligible for ICR Sponsorship. If this is your first visa in the UK, support will be provided for costs associated with Visa application.
Job Details
Under the guidance of Professor Kamil Kranc, we are seeking to recruit a Postdoctoral Training Fellow to pursue therapeutic targeting of the cellular oxygen-sensing system in order to eliminate leukaemic stem cells in acute myeloid leukaemia (AML) and develop effective treatments for this devastating disease. We have identified inhibition of hypoxia-inducible factor (HIF) hydroxylases (PHDs) as a promising non-toxic strategy to target leukaemic stem cells by modulating HIF signalling. The postholder will investigate how inactivation of PHDs and related enzymes impacts AML biology, identify AML subtypes sensitive to these interventions, evaluate novel small-molecule inhibitors in vivo, and discover synthetic lethal vulnerabilities and resistance mechanisms to inform optimal combination strategies and overcome therapeutic resistance.
About You
- PhD in hypoxia biology, biochemistry, cell biology, molecular biology, stem cell biology, oncology or chemical biology.
- Significant experience in hypoxia biology/biochemistry, stem cell biology, and cancer research.
- Previous postdoctoral experience in hypoxia and/or leukaemia biology.
- Confirmation on awarded PhD is required within 6 months of employment.
What We Offer
- A dynamic and supportive research environment
- Access to state-of-the-art facilities and professional development opportunities
- Collaboration with leading researchers in the field
- Competitive salary and pension
About The Institute Of Cancer Research
The ICR is committed to supporting overseas applicants applying for roles. The Institute of Cancer Research, London, is one of the world's most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. Further information about working at the ICR can be found here.
Diversity and Inclusion
We champion diversity as we believe it fuels innovation and drives impactful research. We welcome applicants from all walks of life, valuing diverse perspectives that enrich our work. We are committed to being an equal opportunity for all, regardless of ethnicity, gender, age, sexual orientation, disability, or any other dimension of diversity. Join us in creating an inclusive environment where everyone's voice is heard and valued.
Postdoctoral Training Fellow in Hypoxia and Leukaemia Biology employer: The Institute Of Cancer Research
Contact Detail:
The Institute Of Cancer Research Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Postdoctoral Training Fellow in Hypoxia and Leukaemia Biology
✨Tip Number 1
Network like a pro! Reach out to your contacts in the field of hypoxia and leukaemia biology. Attend conferences, seminars, or even local meet-ups to connect with researchers and professionals who might know about opportunities that aren't advertised.
✨Tip Number 2
Prepare for interviews by brushing up on your knowledge of HIF signalling and its implications in AML. We recommend doing mock interviews with friends or colleagues to get comfortable discussing your research and how it relates to the role.
✨Tip Number 3
Showcase your passion for cancer research! When you get the chance to speak with potential employers, share your enthusiasm for tackling leukaemia and how your background aligns with their goals. This can really set you apart from other candidates.
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets seen by the right people. Plus, we love seeing candidates who are proactive about their job search!
We think you need these skills to ace Postdoctoral Training Fellow in Hypoxia and Leukaemia Biology
Some tips for your application 🫡
Tailor Your CV: Make sure your CV is tailored to highlight your experience in hypoxia biology and leukaemia research. We want to see how your skills align with the role, so don’t be shy about showcasing relevant projects or publications!
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you’re passionate about this research area and how your background makes you a perfect fit for our team. Keep it engaging and personal – we love to see your enthusiasm!
Highlight Your Research Experience: When detailing your research experience, focus on specific techniques and methodologies you've used that relate to the role. We’re particularly interested in your work with hypoxia-inducible factors and any innovative approaches you've taken in your past projects.
Apply Through Our Website: Don’t forget to apply through our website! It’s the best way to ensure your application gets to us directly. Plus, you’ll find all the details you need about the role and our institute there. We can’t wait to hear from you!
How to prepare for a job interview at The Institute Of Cancer Research
✨Know Your Research Inside Out
Make sure you’re well-versed in the latest findings related to hypoxia and leukaemia biology. Brush up on key studies, especially those involving HIF hydroxylases and their role in AML. This will not only show your expertise but also demonstrate your genuine interest in the field.
✨Prepare for Technical Questions
Expect to dive deep into your technical knowledge during the interview. Be ready to discuss your previous research experiences, methodologies you've used, and how they relate to the role. Practising answers to common technical questions can help you feel more confident.
✨Showcase Your Collaborative Spirit
The role involves working with leading researchers, so highlight your teamwork skills. Share examples of past collaborations and how you contributed to a successful project. This will illustrate that you’re not just a great researcher, but also a team player.
✨Ask Insightful Questions
Prepare thoughtful questions about the research environment, ongoing projects, and future directions of the lab. This shows that you’re not only interested in the position but also eager to contribute to the team’s success and growth.
