At a Glance
- Tasks: Lead innovative research on epigenetic tumour dormancy in breast cancer.
- Company: Join the Institute of Cancer Research, a global leader in cancer research.
- Benefits: Competitive salary, professional development, and access to state-of-the-art facilities.
- Other info: Dynamic environment with excellent career growth opportunities and commitment to diversity.
- Why this job: Make a real impact in cancer research and collaborate with top scientists.
- Qualifications: PhD in relevant fields and strong knowledge of chromatin biology required.
The predicted salary is between 45600 - 45600 £ per year.
Key Information
- Salary: From £45,600 per annum. Dependent on relevant Postdoctoral experience. Future progression is based on annual performance review.
- Duration of Contract: Fixed Term for 2 years in the first instance
- Hours per week: 35 hours per week (Full Time)
- Location: Chelsea
- Closing Date: 2nd September 2026
This role is eligible for ICR Sponsorship. If this is your first visa in the UK, support will be provided for costs associated with Visa application. If you are considering relocating to the UK, further information can be found here.
Under the guidance of Professor Luca Magnani, we are seeking to recruit a Postdoctoral Training Fellow to join the Epigenetic Plasticity and Evolution Group, taking ownership of a mature experimental and analytical resource and drive the mechanistic phase of the project. The successful candidate will design and execute mechanistic experiments in long-term ER-positive breast cancer models, perturb candidate chromatin regulators, profile the resulting cell states and integrate the experiments with existing multi-omic datasets. You will work closely with experimental, computational and translational collaborators and will lead manuscripts arising from the work.
About you
The successful candidate must have:
- PhD (or thesis submitted) in cancer biology, epigenetics, genomics, molecular biology or closely related discipline
- Strong knowledge of chromatin biology, epigenetic gene regulation and transcription and of mammalian cell and molecular biology
- Working knowledge of quantitative experimental design and statistics, and an ability to design mechanistic experiments with clear controls and interpretable endpoints
Candidates who are nearing completion of their PhD may apply, but confirmation on awarded PhD is required within 6 months of employment. The ICR has a workforce agreement stating that Postdoctoral Training Fellows can only be employed for up to 7 years as PDTF at the ICR, providing total postdoctoral experience (including previous employment at this level elsewhere) does not exceed 7 years.
Team Information
This position is based in the Breast Cancer Epigenetics and Evolution Team, led by Professor Luca Magnani, within the Division of Breast Cancer Research at The Institute of Cancer Research in Chelsea, London. The lab studies how ER-positive breast cancer cells adapt to endocrine therapy without relying on canonical resistance mutations. We combine long-term evolutionary models, lineage tracing, functional perturbation and multi-omic profiling to identify mechanisms that allow residual cells to enter dormancy and later resume growth.
What we offer
- A dynamic and supportive research environment
- Access to state-of-the-art facilities and professional development opportunities
- Collaboration with leading researchers in the field
- Competitive salary and pension
We encourage all applicants to access the job pack attached for more detailed information regarding this role.
About The Institute of Cancer Research
Why work for us? As a member of staff, you'll have exclusive access to a range of staff benefits. The ICR is committed to supporting overseas applicants applying for roles. The Institute of Cancer Research, London, is one of the world's most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. Further information about working at the ICR can be found here.
At the Institute of Cancer Research, we champion diversity as we believe it fuels innovation and drives impactful research. We welcome applicants from all walks of life, valuing diverse perspectives that enrich our work. Don't let a checklist of qualifications hold you back – if you're passionate about the role, we want to hear from you. Your unique experiences and backgrounds contribute to the richness of our team. We are committed to being an equal opportunity for all, regardless of ethnicity, gender, age, sexual orientation, disability, or any other dimension of diversity. Join us in creating an inclusive environment where everyone's voice is heard and valued.
Postdoctoral Training Fellow - Epigenetic Tumour Dormancy employer: The Institute Of Cancer Research
The Institute of Cancer Research is an exceptional employer, offering a dynamic work environment in Sutton, Surrey, where innovation and collaboration thrive. With a strong commitment to employee growth, we provide access to exclusive benefits and flexible working options, ensuring a healthy work-life balance. Our dedication to diversity and inclusion fosters a culture where every voice is valued, making it a rewarding place for professionals passionate about advancing cancer research.
Contact Details:
The Institute Of Cancer Research Recruitment Team
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