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- Tasks: Lead innovative research in pluripotent stem cells and gene editing at a world-class facility.
- Company: Join the Francis Crick Institute, Europe's largest biomedical research hub, driving vital health discoveries.
- Benefits: Enjoy 28 days leave, pension contributions, mental health support, and discounted gym memberships.
- Why this job: Be part of a collaborative culture that values creativity and scientific exploration.
- Qualifications: PhD or equivalent experience in biological sciences with extensive lab experience required.
- Other info: Visa sponsorship available for international applicants.
The predicted salary is between 49955 - 69955 £ per year.
Job Title: Principal Laboratory Research Scientist – Human Biology Facility
Reports to: Head of Lab Operations – Daria Paruzina
This is a full-time permanent position on Crick terms and conditions of employment.
Salary: From £49,955, subject to skills and experience, with benefits
About us…
The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases, and neurodegenerative conditions.
The Crick is a place for collaboration, innovation, and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture.
About the role…
The Human Models Core (HMC) is an integral part of the Human Biology Facility. Operated by a team of scientific and technical experts, the HMC offers a portfolio of services and support to researchers. Working closely with the Human Biology Governance Team and research groups at the Crick, the HMC facilitates a broad spectrum of human models research.
The HMC team is involved in developing key models for human disease by reprogramming somatic cells into pluripotent stem cell lines and assisting with downstream applications like gene editing and differentiation. Additionally, we provide and maintain a well-equipped communal laboratory space which facilitates interaction between the groups working with human models, pluripotent stem cells, and gene editing.
We are seeking a highly motivated, proactive stem cell expert with deep knowledge and understanding in reprogramming pluripotent stem cells (PSC), differentiation, and gene editing. The successful candidate will take the lead on reprogramming projects, support and advise on differentiation projects, gene editing projects, and the generation of human 2D and 3D models.
As a Principal Laboratory Research Scientist , you will:
- Identify, manage, and deliver robust scientific support to Crick Researchers
- Project delivery of reprogramming portfolio
- Support gene editing projects in PSC
- Reprogram somatic cells to pluripotent stem cells
- Establish new methodologies in the lab
- Develop proof-of-concept for new research directions
- Horizon scanning and developing specific scientific projects and platforms within the facility in a collaborative setting
- Support research groups and Head of Lab ops in grant writing and publications
- Provide tissue culture, quality control, and technical support to research groups within the Francis Crick Institute
- Teach and train scientists in best practice skill sets necessary to grow, characterise, differentiate, and bank human pluripotent stem cells
About you…
You will bring:
- Degree in a biological subject with substantial post-graduate experience in pluripotent stem cell research
- PHD or equivalent experience
- Extensive wet lab experience in pluripotent cell culture
- Experience in reprogramming cells to pluripotency
- Proven track record in scientific publication
- Demonstrable experience with best practice, quality control assessment, and related assays
- Excellent communication and presentation skills
- Excellent organisational skills and record keeping with attention to detail
- Ability to prioritise workflows and deliver to deadlines
- Highly self-motivated with a pro-active approach
About Working at the Crick…
Our values
- We are bold . We make space for creative, dynamic, and imaginative ideas and approaches.
- We are open . We’re highly collaborative and interactive.
- We are collegial . We show respect for one another, work cooperatively, and support the wider community.
At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances.
What will you receive?
- Visas – The Crick offers funding for those requiring a visa to work in the UK.
- Generous Leave : 28 days of annual leave, plus three additional days over Christmas and bank holidays.
- Pension Scheme : Defined contribution pension with employer contributions of up to 16%.
- 24/7 GP consultation services.
- Occupational health services and mental health support programs.
- Eye care vouchers and discounted healthcare plans.
- Work-Life Balance :
- Back-up care for dependents.
- Childcare support allowance.
- Annual leave purchase options.
- Discounted gym memberships, bike-to-work scheme, and shopping discounts.
- Subsidised on-site restaurant and social spaces for team interaction.
Development & Recognition : Comprehensive training, mentoring, and a pay structure with performance-linked progression.
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Principal Laboratory Research Scientist - Human Biology Facility employer: The Francis Crick Institute Limited
Contact Detail:
The Francis Crick Institute Limited Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Principal Laboratory Research Scientist - Human Biology Facility
✨Tip Number 1
Familiarize yourself with the latest advancements in pluripotent stem cell research. Being well-versed in current methodologies and breakthroughs will not only enhance your knowledge but also demonstrate your commitment to the field during discussions.
✨Tip Number 2
Network with professionals in the stem cell research community. Attend relevant conferences, workshops, or seminars where you can meet potential colleagues and learn about ongoing projects at the Crick Institute.
✨Tip Number 3
Prepare to discuss your previous research experiences in detail, especially those related to reprogramming somatic cells and gene editing. Be ready to share specific examples of challenges you faced and how you overcame them.
✨Tip Number 4
Showcase your collaborative spirit by highlighting any past experiences where you worked effectively within a team. The Crick values collegiality, so demonstrating your ability to work well with others will be crucial.
We think you need these skills to ace Principal Laboratory Research Scientist - Human Biology Facility
Some tips for your application 🫡
Understand the Role: Make sure to thoroughly read the job description and understand the key responsibilities and qualifications required for the Principal Laboratory Research Scientist position. Tailor your application to highlight your relevant experience in pluripotent stem cell research and gene editing.
Highlight Relevant Experience: In your CV and cover letter, emphasize your extensive wet lab experience, particularly in reprogramming cells to pluripotency and any proven track record in scientific publication. Use specific examples to demonstrate your expertise and achievements in these areas.
Showcase Your Skills: Clearly outline your excellent communication, organizational skills, and attention to detail in your application. Mention any experience you have in teaching or training others, as this is a key aspect of the role.
Express Your Motivation: Convey your passion for biomedical research and your proactive approach to scientific challenges in your cover letter. Discuss how your values align with those of the Francis Crick Institute, emphasizing your commitment to collaboration and innovation.
How to prepare for a job interview at The Francis Crick Institute Limited
✨Showcase Your Expertise
Be prepared to discuss your extensive experience in pluripotent stem cell research. Highlight specific projects where you successfully reprogrammed somatic cells and any innovative methodologies you developed.
✨Demonstrate Collaboration Skills
Since the role emphasizes collaboration, share examples of how you've worked with diverse teams in previous positions. Discuss how you facilitated communication and supported others in achieving common goals.
✨Prepare for Technical Questions
Expect in-depth questions about gene editing techniques and quality control assessments. Brush up on the latest advancements in these areas and be ready to explain your approach to maintaining high standards in the lab.
✨Communicate Your Vision
Articulate your vision for future research directions within the Human Biology Facility. Be ready to discuss how you would contribute to the Crick's mission and support grant writing and publications effectively.
