Vice President of Platform in Hartford

The Vice President of Platform is the architect of Scionx Bio’s core technology engine.

Reporting to the CEO and sitting within the company’s senior leadership, this individual owns the entire upstream pipeline—from computational design and AI-driven sequence optimisation through to the formulation and delivery systems that carry our molecules into the body, and onward into the evolution of our next-generation x RNA modalities.

This is a rare opportunity to lead and continue to build the platform that defines the company, setting its scientific direction, shaping a multidisciplinary team of exceptional scientists and engineers, and translating a validated modality into a durable, defensible, and endlessly generative source of medicines.

Responsibilities

• Lead the development of proprietary AI/ML models and computational biology pipelines for sequence design, structural prediction, and codon optimisation, with the goal of maximising translation, stability, and tissue specificity.
• Spearhead the continued strategic evolution of our modality, guiding the platform’s advance into ever more sophisticated x RNA chemistries and ensuring that it remains at the state of the art.
• Oversee the formulation engineering team in optimising lipid nanoparticles (LNPs) for targeted, safe, and efficient in vivo delivery, working in collaboration with our strategic advisor.
• Ensure that platform discoveries are robust, reproducible, and engineered from the outset with manufacturing scalability in mind, so that what works at the bench translates reliably towards the clinic.
• Own the resourcing, planning, and timelines for the platform team, and mentor and grow a multidisciplinary group of data scientists, biologists, and engineers into a high‑performing, collaborative whole.
• Actively identify and protect novel sequence motifs, AI design algorithms, and proprietary LNP formulations, building and defending the intellectual property moat that underpins the company’s long‑term value.
• Serve as the pivotal bridge between Platform and Discovery, working closely with chemistry and biology colleagues to transition optimised candidates smoothly from the Platform team into the Discovery team.

Qualifications

• A Ph D in a relevant discipline—e. g., computational biology, bioinformatics, RNA biology, biochemistry, chemical or biomedical engineering—or a closely related field.
• Substantial and progressive experience in RNA, oligonucleotide, or nucleic‑acid therapeutics, gained over a senior industry career.
• A demonstrable track record of building and leading platform or technology functions in a biotech or pharmaceutical setting, including direct leadership of multidisciplinary teams spanning computation, biology, and engineering.
• Deep, hands‑on familiarity with the application of AI and machine learning to molecular design, together with a genuine understanding of the experimental science the platform serves.
• Strong knowledge of delivery technologies, in particular LNP formulation for nucleic acids, and of the considerations that carry a discovery‑stage platform towards manufacturable, scalable processes.
• A record of intellectual property generation, and the strategic instinct to recognise and protect what is defensible.
• Outstanding leadership, communication, and collaboration skills, with the ability to operate effectively across a geographically distributed, multicultural organisation and to translate between technical and strategic audiences.

The following reflects the profile we expect this role to require; we welcome candidates who meet the substance of it even where their path has been unconventional.

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