Senior Director Trial Optimization and Feasibility in Chester

We’re Teva, a leading innovative biopharmaceutical company, enabled by a world-class generics business. Whether it’s innovating in the fields of neuroscience and immunology or delivering high-quality medicine worldwide, we’re dedicated to addressing patients’ needs now and in the future. Here, you will be part of a high-performing, inclusive culture that values fresh thinking and collaboration. You'll have the room to grow, the flexibility to balance life with work, and the opportunity to better health worldwide, together.

The Senior Director, Head of Trial Optimization & Feasibility (TOF), is a strategic enterprise leader accountable for defining and governing the sponsor‑side feasibility, enrollment forecasting, and protocol optimization model across a global, highly outsourced clinical development organization. This role provides authoritative guidance, sets the strategic direction for feasibility excellence, and ensures all enrollment, country, and site assumptions are evidence‑driven, risk‑adjusted, and operationally sound before advancing to governance.

As the organization’s central decision maker on feasibility integrity, this leader influences functions across R&D - Clinical Operations, Clinical Development, Medical Affairs, Analytics, and Vendor Alliance teams, driving alignment on strategic enrollment strategies and challenging assumptions with confidence and rigor. The Head of TOF builds and leads a high‑performing analytics function, elevates modeling sophistication, and embeds standardized frameworks that improve forecast accuracy and strengthen portfolio performance.

Operating as a trusted advisor to senior leadership, this role shapes enterprise standards, anticipates and mitigates operational risk, and ensures feasibility is treated as a strategic differentiator. Through strategic insight, operational leadership, and strong cross‑functional influence, the Head of TOF accelerates decision‑making, improves predictability, and drives accountability, transparency, and continuous improvement across the global development portfolio. This role will also own and contribute elements of Sustainability including, but not limited to, DCT, Patient Surveys and Data, Tokenization, DHT, TA level patient burden assessment, Diversity.

The role is accountable for establishing and governing Teva’s sponsor-side trial optimization and feasibility capability, including validating CRO assumptions, developing evidence-based enrollment forecasts, shaping country and site strategies, and leading protocol operability reviews to improve study execution. The leader will build internal feasibility analytics, challenge and endorse key enrollment and startup assumptions, incorporate patient burden, diversity, DCT, digital health, and sustainability considerations, and drive continuous improvement by comparing forecasted versus actual performance across studies, countries, therapeutic areas, and CRO partners.

Your Skills and Experience

• 12+ years of global clinical development experience, including significant trial optimization and feasibility leadership in innovative portfolios.
• Demonstrated experience in global, complex trial environments.
• Proven ability to challenge and validate CRO enrollment assumptions in outsourced models.
• Bachelor’s Degree.

Feasibility Governance & Validation Authority

• Define sponsor-side evidence standards required for all CRO feasibility packages and assessments.
• Independently assess enrollment rates, screen failure assumptions, startup timelines, and country allocation logic.
• Lead structured challenge sessions with CRO partners.
• Endorse projections prior to governance or formally escalate unrealistic assumptions to senior leadership.

Internal Feasibility Analytics & Forecasting

• Build and lead an internal feasibility analytics capability.
• Develop and maintain enrollment forecasting models incorporating epidemiology, historical performance, protocol burden, site and patient burden and competitive intelligence.
• Oversight of scenario modeling (base case, risk-adjusted, upside/downside).
• Continuously recalibrate models based on live portfolio performance.

Country & Site Strategy Endorsement

• Design and maintain sponsor-side methodology for country and site allocation.
• Validate CRO-recommended site selection strategies.
• Incorporate diversity objectives, competitive landscape analysis, and startup capacity realities.
• Inform and endorse final country/site strategy prior to execution.

Protocol Optimization

• Lead structured operability reviews prior to protocol finalization.
• Quantify operational complexity drivers impacting startup and enrollment.
• Facilitate cross-functional trade-off discussions to reduce avoidable downstream risk.

Forecast Accountability & Continuous Improvement

• Conduct post-study projected vs. actual reconciliation for enrollment, startup timelines, and key assumptions.
• Quantify variance at study, therapeutic area, country, and CRO levels.
• Identify systemic bias trends and embed lessons learned into updated modeling frameworks.
• Report forecast accuracy performance trends to executive governance.

Also Good to Have

• Experience in Neuroscience and Immunology preferred.
• Advanced degree in a scientific, engineering, or supply chain discipline preferred.

Leadership: The ability to empower, grow, develop, and inspire high performing teams and individuals by providing them with clear direction linked to organizational goals.

Results and Performance-Driven: Assumes personal ownership and accountability for business results and solutions; consistently delivers results that meet or exceed expectations; makes the customer central to all thinking; keeps the focus on driving customer value.

Strong Interpersonal and People Skills: The successful candidate will have a proven background interacting with individuals at a variety of functional levels with both internal and external personnel, and the ability to perform cross-functionally.

Excellent Communication Skills, both Written and Oral: The successful candidate’s communication style should be diplomatic and direct, but not confrontational. He or she must be able to summarize executive level information in an articulate, clear, tangible manner both in written form and orally.

Collaboration and Team Work: Puts interests of enterprise above own; works well across functions and groups; builds teams effectively; inspires followership; instills an enterprise mindset.

Sense of Urgency: Proactively senses and responds to problems and opportunities; works to reduce “cycle” time; takes action when needed.

Accountability: The successful candidate must be able to effectively assume accountability for their actions. He or she should be a results-oriented team player who leads by example, holds him/herself accountable for performance, and champions all aspects of assigned areas while remaining detail-oriented.

Salary Range: The annual starting salary for this position is between £202,000 - £252,700 annually. Factors which may affect starting salary within this range and level of role may include geography/market, skills, education, experience and other qualifications of the successful candidate.

How We’ll Take Care of You: We offer a competitive benefits package, including:

• Comprehensive Health Insurance: Medical, Dental, Vision, and Prescription coverage starting on the first day of employment, providing the employee enrolls.
• Retirement Savings: 401(k) with employer match, up to 6% and an annual 3.75% Defined Contribution to the 401k plan.
• Time Off: Paid Time Off including vacation, sick/safe time, caretaker time and holidays.
• Life and Disability Protection: Company paid Life and Disability insurance.
• Additional benefits include, but are not limited to, Employee Assistance Program, Employee Stock Purchase Plan, Tuition Assistance, Flexible Spending Accounts, Health Savings Account, Life Style Spending Account, Volunteer Time Off, Paid Parental Leave, if eligible, Family Building Benefits, Virtual Physical Therapy, Accident, Critical Illness and Hospital Indemnity Insurances, Identity Theft Protection, Legal Plan, Voluntary Life Insurance and Long Term Disability and more.

The total compensation may also include restricted stock units and discretionary awards, depending on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment.

Please advise us of any accommodations needed to support you throughout the recruitment and selection process. All accommodation information provided will be treated as confidential and used only for the purpose of providing an accessible candidate experience. Request a reasonable accommodation by sending an email to AskHR@tevapharm.com with the nature of your request and your contact information. Only inquiries concerning a request for a reasonable accommodation will be responded to from this email address.

Teva Pharmaceuticals is committed to equal opportunity in employment. It is Teva's policy that equal employment opportunity be provided without regard to age, race, creed, color, religion, sex, disability, pregnancy, medical condition, genetic information, marital status, sexual orientation, gender identity or expression, ancestry, national or ethnic origin, citizenship status, military status or status as a disabled or protected veteran, or any legally recognized status entitled to protection under applicable federal, state, or local laws.