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- Tasks: Join our team to develop and optimise AAV vectors for gene therapy.
- Company: Innovative biotech firm in Cambridge, revolutionising DNA synthesis and gene therapy.
- Benefits: Competitive salary, private pension, and opportunities for career progression.
- Why this job: Be part of a cutting-edge company making a real impact in biotechnology.
- Qualifications: BSc/MSc in biology with AAV production experience in mammalian cell lines.
- Other info: Work in a collaborative environment with ongoing training and support.
The predicted salary is between 30000 - 40000 £ per year.
Salary: £30,000 – £40,000 depending on experience, this may differ.
Our client is an innovative biotechnology company based outside of the centre of Cambridge. They have built an enzymatic platform to synthesise DNA, providing exciting possibilities for ensuring cheaper, faster and more accurate DNA / RNA / gene constructs than traditional plasmid-based methods. They also supportdrug discovery projects within the gene therapy sector using adeno-associated viruses (AAV). In a key phase of their growth, our client is looking to bring a Scientist into the team to support the AAV and cell biology section of the business. This role will require the successful candidate to have previous AAV expression experience within mammalian cell lines (HEK-293 etc)
The Opportunity
This is an opportunity for a scientist who holds a BSc/MSc in a Biology focused role with at least one year of experience within AAV expression and production. This can be gained during your degree, or in industry. This role will involve the following:
- Development and optimisation of AAV vectors for use within gene therapy products.
- Production and purification of AAVs using mammalian cell culture systems (HEK 293).
- Being part of process improvement initiatives for AAV production.
- Laboratory analysis of the AAVs using SDS-PAGE, qPCR, flow cytometry, ELISA, gel electrophoresis etc.
- Recording of data and ensuring the data is up to date and reliable.
- Participate in team meetings and trainings as and when required.
- Support in other areas of the business as and when required.
- Following of laboratory and company SOPs.
Skills and Experience Needed
The ideal candidate will have the following:
- BSc / MSc / PhD in a biological / biotechnology discipline (essential)
- Extensive AAV production experience using HEK 293 cells (essential)
- Must be competent in various aspects of AAV production e.g. transfection, mammalian cell culture, AAV purification (essential)
- Strong experience in some laboratory analysis techniques such as ELISA, SDS-PAGE, western blotting, qPCR, flow cytometry (essential to be confident in the use of some of these)
- Prior experience in bacterial cloning (desired)
The Package
As an up-and-coming Cambridge Biotech, our client is able to offer a competitive salary, progression options and benefits package including private pension.
To Apply
If you would like to apply to this opportunity, please send a copy of your CV to Charlie Cox at – alternatively, please call Charlie on 07903 204577.
I\’m interested in this job
Please use the form provided to get in touch with us and we will respond as soon as possible.
Compulsory fields are in bold .
I\’m interested in this job
Please use the form provided to get in touch with us and we will respond as soon as possible.
Compulsory fields are in bold .
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Your file must be in one of the following formats: pdf , doc , docx , rtf , txt and no larger than 2MB .
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AAV Scientist employer: taylorollinson Ltd
Contact Detail:
taylorollinson Ltd Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land AAV Scientist
✨Tip Number 1
Network with professionals in the biotechnology field, especially those who have experience with AAV production. Attend relevant conferences or seminars where you can meet potential colleagues and learn more about the latest advancements in gene therapy.
✨Tip Number 2
Familiarise yourself with the specific laboratory techniques mentioned in the job description, such as ELISA, SDS-PAGE, and qPCR. Consider taking online courses or workshops to enhance your skills and demonstrate your commitment to mastering these methods.
✨Tip Number 3
Prepare to discuss your previous AAV expression experience in detail during interviews. Be ready to explain the challenges you faced and how you overcame them, as well as any successful projects you've contributed to in the past.
✨Tip Number 4
Stay updated on the latest research and developments in AAV technology and gene therapy. This knowledge will not only help you in interviews but also show your genuine interest in the field and the company’s work.
We think you need these skills to ace AAV Scientist
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights your relevant experience in AAV expression and production, particularly with mammalian cell lines like HEK-293. Emphasise any specific techniques you are proficient in, such as ELISA or qPCR.
Craft a Strong Cover Letter: Write a cover letter that clearly outlines your passion for biotechnology and gene therapy. Mention how your background aligns with the company's innovative approach and their enzymatic platform for DNA synthesis.
Highlight Relevant Skills: In your application, be sure to list your skills related to AAV production, including transfection and mammalian cell culture. Provide examples of how you've used these skills in previous roles or projects.
Follow Application Instructions: Ensure you follow the application instructions carefully. Upload your CV in the specified formats (pdf, doc, docx, rtf, txt) and keep the file size under 2MB. Double-check that all compulsory fields are filled out before submitting.
How to prepare for a job interview at taylorollinson Ltd
✨Know Your AAV Basics
Make sure you brush up on your knowledge of adeno-associated viruses and their role in gene therapy. Be prepared to discuss your previous experience with AAV expression and production, especially using HEK-293 cells.
✨Showcase Your Lab Skills
Highlight your proficiency in laboratory techniques such as ELISA, SDS-PAGE, and qPCR. Be ready to provide specific examples of how you've used these techniques in past projects or during your studies.
✨Demonstrate Problem-Solving Abilities
Discuss any process improvement initiatives you've been involved in, particularly related to AAV production. Employers love candidates who can think critically and contribute to enhancing lab processes.
✨Prepare Questions for the Interviewers
Have a few thoughtful questions ready about the company's projects, team dynamics, or future goals. This shows your genuine interest in the role and helps you assess if the company is the right fit for you.
