At a Glance
- Tasks: Lead the development of advanced in vitro models for groundbreaking gene therapy research.
- Company: Exciting biotech start-up focused on transformative gene therapies.
- Benefits: Competitive salary, private healthcare, life insurance, and equity options.
- Other info: Collaborative environment with opportunities for significant career growth.
- Why this job: Make a real impact on patients' lives through innovative science.
- Qualifications: PhD in life sciences and experience in complex cell culture models.
The predicted salary is between 65000 - 78000 £ per year.
Oxford | On-site | Start-up Biotechnology Company
Talentmark is partnering with a biotech start-up developing next-generation gene therapies for severe genetic diseases. With a highly collaborative scientific team and innovative platform technologies, the company is advancing cutting-edge preclinical programmes focused on delivering transformative therapies to patients with high unmet need.
This is an exciting opportunity for a talented scientist to play a key role in establishing advanced in vitro models that support the discovery and optimisation of novel gene therapy vectors. Working within a highly collaborative research team, you'll help develop physiologically relevant models that accelerate the translation of cutting-edge science into life-changing therapies. This opportunity is available at Senior Scientist or Principal Scientist level, depending on your experience and technical expertise.
The Role:
As a Senior or Principal Scientist, you'll lead the development of complex in vitro systems, including 3D cultures, co-cultures, organoids and organ-on-a-chip platforms, with a particular focus on generating robust models to evaluate gene therapy vector performance. This is a predominantly hands-on laboratory position.
Responsibilities:
- Design, establish and optimise advanced in vitro models, including 3D cultures, organoids, co-cultures and organ-on-a-chip systems.
- Develop physiologically relevant tissue models using primary cells, with a particular interest in kidney biology.
- Design and execute assays to assess vector transduction, transgene expression and safety.
- Generate, analyse and interpret complex biological datasets to support research decisions.
- Work closely with multidisciplinary teams across vector engineering, in vivo research and delivery technologies.
- Maintain high laboratory standards and contribute to multiple research programmes simultaneously.
Your Background:
- PhD in a relevant life sciences discipline and bring industry experience within biotechnology, pharmaceuticals or translational research environments.
- Proven experience developing complex in vitro cell culture models (3D cultures, organoids and/or co-cultures).
- Strong hands-on mammalian cell culture experience, including primary cells.
- Excellent molecular and cellular biology laboratory skills.
- Experience analysing complex biological data.
Highly Desirable:
- Experience developing organ-on-a-chip or microphysiological systems.
- Primary kidney cell culture or renal model experience.
- Gene therapy, viral vector or advanced therapeutics experience.
If you're passionate about developing advanced in vitro models and want to contribute to pioneering gene therapy research with real patient impact, we'd love to hear from you.
Why Apply:
- Help develop next-generation gene therapies that have the potential to transform the lives of patients with genetic diseases.
- Lead cutting-edge research using advanced in vitro models, including organoids, 3D cultures and organ-on-a-chip technologies.
- Join a collaborative, venture-backed biotech where you'll work alongside expert scientists and have a direct impact on research and innovation.
- Bonus, private healthcare insurance, life insurance, and an equity options scheme.
It is essential that applicants hold entitlement to work in the UK. Please quote job reference in all correspondence.
Senior / Principal Scientist, In Vitro Models in Oxford employer: Talentmark
At Talentmark, we pride ourselves on being an exceptional employer, offering a dynamic work environment that fosters innovation and collaboration. Our hybrid model allows for flexibility while working with a leading global pharmaceutical company, providing employees with unique opportunities for professional growth in the fields of NLP and AI. With a strong emphasis on employee development and a supportive culture, we empower our team to make meaningful contributions to the scientific community.
StudySmarter Expert Advice🤫
We think this is how you could land Senior / Principal Scientist, In Vitro Models in Oxford
✨Get Involved in Local Research Communities
Tap into local biotechnology meetups and research forums. These are great places to mingle with industry professionals, share your passion, and even discover unadvertised job openings. It's all about getting your face known in the field!
✨Leverage University Alumni Networks
If you're a recent grad, don’t underestimate the power of your university’s alumni network! Reach out to alumni working in biotechnology to gather tips about job openings at companies like Talentmark. You'd be surprised how willing people are to help out a fellow grad!
✨Show Off Your Projects
Curate a portfolio showcasing any research projects or internships you've completed in biotechnology. This tangible evidence of your skills can really impress employers when you chat with them at networking events or interviews. It's about making that killer first impression!
✨Stay Up-to-Date with Industry Trends
Biotech is a fast-paced field, so keeping yourself updated with the latest advancements is crucial. Attend industry conferences, webinars, or workshops to broaden your knowledge and meet potential employers. Plus, it’ll give you fantastic talking points for your interviews at places like Talentmark!
We think you need these skills to ace Senior / Principal Scientist, In Vitro Models in Oxford
Some tips for your application 🫡
Show Off Your Lab Skills:In the biotechnology field, it's super important to highlight your lab experience in your CV. Be sure to mention specific techniques or instruments you've mastered (think PCR, gel electrophoresis, etc.) and any relevant projects you've worked on. This will show Talentmark that you have the hands-on skills they need.
Tailor Your Technical Skills:Make sure to emphasise your technical skills, especially those relevant to the biotechnology sector. Include any software tools or programming languages you've used, like R or Python for data analysis, which could be key for this role at Talentmark.
Craft a Compelling Cover Letter:Since this is a full-time role, your cover letter should reflect not only your passion for biotechnology but also your long-term career ambitions. Share why you're excited about the work that Talentmark does and how you envision contributing to their goals. This shows that you’re not just looking for any job, but you're genuinely invested in this opportunity.
Include Your Papers and Projects:If you've published any papers or contributed to significant projects, mention them! These documents can boost your application and provide tangible evidence of your expertise in the biotechnology field. Don’t forget to link to any relevant publications or project summaries—this can set you apart from other candidates.
How to prepare for a job interview at Talentmark
✨Brush Up on Lab Techniques
Since you're eyeing a full-time gig in biotechnology, make sure you're well-versed in the lab techniques relevant to the role. Be ready to talk about PCR, CRISPR, or any specific methods mentioned in the job description at Talentmark. You might even be asked to demonstrate your understanding of these processes.
✨Know Your Bioinformatics Tools
Get comfortable with bioinformatics tools that are commonly used in the industry, like BLAST or Bioconductor. These are key in biotechnology, and having hands-on experience or at least familiarity can set you apart. Prepare to discuss any relevant projects you've worked on, especially if they involved data analysis or genomic research.
✨Show Your Teamwork Skills
Biotech often involves collaboration across multiple disciplines. Be ready to share stories that highlight your teamwork and communication skills, especially in research projects. Think about working with different teams at university or any internships – this is where you can show how well you fit into Talentmark's culture.
✨Research Recent Biotech Innovations
Stay updated on the latest trends and breakthroughs in biotechnology. Knowing what's happening in the field can help you engage in more meaningful discussions during your interview. Bring up recent articles or advancements that excite you, especially those related to the work being done at Talentmark. This shows your passion for the industry!
