Company Description
TACHMED is an early-stage medical device company developing connected in vitro diagnostic systems comprising biochemical assays, hardware instrumentation, and regulated software and algorithms. The company conducts in-house R&D and validation activities, with outsourced commercial manufacturing. This role will play a critical role in driving the development, validation and translation of electrochemical biosensor assays from early feasibility through scalable, regulatory-ready prototypes.
Role Description
The Electrochemical Scientist role encompasses assay optimisation, analytical validation, stability studies, matrix adaptation, and collaboration with manufacturing to ensure robustness and reproducibility in a medical device development environment. The Electrochemical Scientist reports to the Senior Product Manager. The role is on‑site at the West London laboratory.
Role Responsibilities
Assay Development, Optimisation & Validation
- Design and execute electrochemical experiments for development of biomarker assays (proteins, infectious disease targets, electrolytes, inflammatory markers)
- Optimise electrode functionalisation, surface chemistry, and assay workflows (gold and graphene electrodes)
- Lead matrix adaptation of assays (buffer → serum → plasma → whole blood), addressing interference, fouling, and variability
- Translate proof‑of‑concept assays into robust, reproducible prototypes suitable for point‑of‑care deployment
- Design and execute analytical validation studies (LOD, LOQ, precision, linearity, specificity, interference, reproducibility)
- Plan and conduct stability and robustness studies (reagent stability, electrode stability, environmental stress testing)
- Apply Design of Experiments (DoE) and statistical analysis to drive assay optimisation and robustness
- Evaluate materials, membranes, and reagents for performance, manufacturability, and scalability
- Maintain detailed experimental documentation and present findings to internal stakeholders.
Technical Leadership & Collaboration
- Mentor and support junior scientists and laboratory staff
- Contribute to project planning and cross‑functional coordination
- Work closely with product, regulatory, and clinical teams to support assay translation and validation
Regulatory & Quality Alignment
- Design and document experiments in alignment with IVD regulatory expectations (ISO 13485, FDA QSR, IVDR where applicable)
- Ensure traceability of materials, reagents, instruments, and data
- Contribute to analytical validation reports and technical documentation
- Support risk assessment activities (e.g., FMEA, assay failure mode analysis)
- Collaborate with manufacturing partners to support assay transfer, process robustness, and reproducibility
- Contribute to development of scalable assay protocols suitable for pilot and early manufacturing builds.
Key Competencies
- Electrochemical techniques and instrumentation
- Surface functionalisation and biomolecule immobilisation
- Assay design, optimisation, and validation workflows
- Statistical analysis and DoE
- Technical documentation and regulatory awareness
- Problem‑solving and experimental design
- Cross‑functional collaboration in multidisciplinary teams
- Adaptability in a fast‑paced startup R&D environment.
Skills
- Proven expertise in electrochemical biosensors
- Hands‑on experience with electrochemical techniques (EIS, DPV, SWV, CA)
- Experience in regulated or quality‑controlled development environments preferred
- Proactive attitude and ability to self‑manage
- Attention to detail
- Good communication skills (verbal and written)
- Excellent organisational skills
- Strong scientific communication skills
- Knowledge of Microsoft 365.
Qualifications
- 2+ years of relevant assay development experience
- (Desired) Masters in Electrochemistry, Materials Science, Chemical Engineering, or a biology‑related field
- (Desired) Ph.D. in Electrochemistry, Materials Science, Chemical Engineering, or a biology‑related field.
#J-18808-Ljbffr
