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- Tasks: Lead innovative bioanalytical projects and mentor the next generation of scientists.
- Company: Join a leading CRO known for scientific excellence and collaboration.
- Benefits: Competitive salary, professional development, and opportunities to present at conferences.
- Why this job: Make a real impact in the field of mass spectrometry and bioanalysis.
- Qualifications: PhD or MSc/BSc with extensive experience in bioanalytical environments.
- Other info: Dynamic role with opportunities for career advancement and industry recognition.
The predicted salary is between 36000 - 60000 £ per year.
The Principal Scientist I (Mass Spectrometry) aids in driving strategic scientific growth within our mass spectrometry group by leading high-impact value-creation initiatives, mentoring junior staff, and expanding in-house capabilities. You will support business development through scientific proposal writing, client interactions, and by serving as a subject-matter expert on advanced bioanalytical assays with predominantly LC-MS endpoints. Your leadership will champion scientific excellence, reinforce GxP compliance, and elevate our CRO’s reputation via publications, workshops, and cross-functional collaborations.
Main Areas of Responsibility
- Business Development & Scientific Strategy: Collaborate with BD teams to develop scientific content for proposals, drive technical discussions with clients, and cultivate long-term relationships. Identify emerging industry needs and oversee Value Creation Projects (VCPs) and advance in-house capabilities to expand our assay portfolio.
- Assay SME & Method Innovation: Lead feasibility studies and perform/oversee method development for the complex bioanalytical assays requested by our clients (including small molecules, large molecules, and new modalities at all stages of the development cycle). Lead transfer of the methods to study delivery group for validation and sample analysis, and monitor study progress as the methods are employed. Serve as the SME for complex bioanalytical assays (scientific rationale, sample preparation, chromatography, mass spectrometry, hybrid applications, troubleshooting etc).
- Leadership & Mentoring: Mentor and train junior and mid-level scientists on advanced assay design, troubleshooting, data analysis, regulatory requirements and GxP documentation. Delegate responsibilities and review deliverables to ensure scientific rigor, data integrity, and on-time delivery.
- Scientific Excellence & External Engagement: Drive continuous improvement through internal audits, protocol enhancements, and corrective-preventive action initiatives. Represent the company at scientific conferences, workshops, and in peer-reviewed publications to showcase our capabilities and thought leadership.
Qualifications & Experience
PhD in Chemistry, Biochemistry, Biology or related discipline with ≥2 years’ industry experience OR MSc/BSc in a relevant field with ≥7 years’ hands-on experience. Deep expertise in regulated bioanalytical environments (GLP/GCP) and familiarity with ICH bioanalytical guidelines. Demonstrated track record leading/performing development of bioanalytical LC-MS assays for PK and/or PD applications in biological fluids and tissues using triple quadrupole instruments. Excellent leadership, project management, and cross-functional collaboration skills. Proven experience in business-facing roles: proposal writing, client presentations, and technical negotiations. Strong written and verbal communication skills in English.
Preferred Skills & Experience
- Experience in the bioanalytical quantitation of large molecules and new modalities using LC-MS.
- History of leading or co-authoring peer-reviewed publications or patents in bioanalysis.
- Performed role of Study Director/Principal Investigator/Responsible Scientist in the support of regulatory studies.
- Bioanalytical CRO experience.
- Experienced user of high-resolution mass spectrometers.
- Experience of interactions with health authorities (FDA, EMA, MHRA).
Principal Scientist I (LCMS/MS) in Macclesfield employer: Synexa Life Sciences (Pty) Ltd.
Contact Detail:
Synexa Life Sciences (Pty) Ltd. Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Principal Scientist I (LCMS/MS) in Macclesfield
✨Network Like a Pro
Get out there and connect with people in the industry! Attend conferences, workshops, or even local meet-ups. You never know who might have a lead on your dream job or can introduce you to someone who does.
✨Show Off Your Expertise
When you get the chance to chat with potential employers, don’t hold back! Share your knowledge about advanced bioanalytical assays and your experience with LC-MS. This will position you as a subject-matter expert and make you stand out.
✨Follow Up After Interviews
After an interview, drop a quick thank-you email to express your appreciation. It’s a great way to reinforce your interest in the role and remind them of your qualifications. Plus, it shows you’re proactive!
✨Apply Through Our Website
Don’t forget to check out our website for job openings! Applying directly through us not only streamlines the process but also shows your genuine interest in being part of our team. Let’s make it happen!
We think you need these skills to ace Principal Scientist I (LCMS/MS) in Macclesfield
Some tips for your application 🫡
Tailor Your CV: Make sure your CV reflects the specific skills and experiences mentioned in the job description. Highlight your expertise in LC-MS assays and any relevant leadership roles you've held. We want to see how you can contribute to our mass spectrometry group!
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you're passionate about bioanalytical science and how your background aligns with our goals at StudySmarter. Don’t forget to mention any experience with business development or client interactions.
Showcase Your Achievements: When detailing your experience, focus on specific achievements that demonstrate your impact in previous roles. Whether it's leading a successful project or publishing a paper, we love to see quantifiable results that highlight your contributions to scientific excellence.
Apply Through Our Website: We encourage you to apply directly through our website for a smoother application process. It helps us keep track of your application and ensures you don’t miss out on any important updates from us!
How to prepare for a job interview at Synexa Life Sciences (Pty) Ltd.
✨Know Your Science Inside Out
Make sure you have a solid grasp of the principles behind LC-MS/MS and bioanalytical assays. Brush up on recent advancements in the field and be ready to discuss your previous experiences with method development and troubleshooting. This will show your expertise and confidence.
✨Prepare for Business Development Questions
Since this role involves client interactions and proposal writing, think about how you can demonstrate your experience in these areas. Prepare examples of successful collaborations or proposals you've worked on, and be ready to discuss how you can contribute to the company's growth.
✨Showcase Your Leadership Skills
As a Principal Scientist, you'll be mentoring junior staff. Be prepared to share your leadership philosophy and provide examples of how you've successfully trained or guided others in the past. Highlight any specific projects where your mentorship made a difference.
✨Engage with Their Vision
Research the company’s recent publications, workshops, and initiatives. During the interview, express your enthusiasm for their work and how you see yourself contributing to their scientific excellence and reputation. This shows that you're not just looking for a job, but are genuinely interested in being part of their mission.
