Principal Biostatistician - Biomarker (EMEA Remote)

Syneos Health® is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities.

Our Clinical Development model brings the customer and the patient to the center of everything that we do. We are continuously looking for ways to simplify and streamline our work to not only make Syneos Health easier to work with, but to make us easier to work for.

Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to accelerate the delivery of therapies, because we are passionate to change lives.

Discover what our 29,000 employees, across 110 countries already know: WORK HERE MATTERS EVERYWHERE.

Why Syneos Health:

• We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
• We are committed to our Total Self culture – where you can authentically be yourself.
• We are continuously building the company we all want to work for and our customers want to work with.

Job Responsibilities:

• Collaborates with representatives from other functions to plan, execute and analyze all biomarker aspects (including genomics) of clinical studies or biomarker studies in the role of the biomarker statistician and assumes the role of project biomarker statistician under guidance of an experienced statistician.
• Develops the Biomarker Evaluation Plan for the study as appropriate, ensuring overall consistency within and between projects.
• Provides statistical input in clinical development discussions and usage of AI and ML approaches.
• Facilitates the overall organization and coordination of statistical activities regarding biomarker research and development activities for specific studies and projects.
• Conduct and design advanced data analysis for genomics and biomarker statistics, including statistical programming, and design complex analysis algorithms.
• Experience with RNA, olink and other biomarker data handling experience.
• Assumes responsibility for the production and accuracy of the Biomarker Evaluation Report with respect to statistical deliverables and interpretation of the results.
• Works independently at routine and complex statistical questions, modeling and tasks.
• Develops and implements standard processes for the analysis of routine (parts of) biomarker assessments.

Qualifications:

• PhD or MSc in Biostatistics, Statistics or Mathematics, or related field.
• Strong communication and interpersonal skills.
• Ability to work independently as well as collaboratively, as required.
• Minimal supervision required.
• Usage of AI and ML approaches.
• Previous experience in independently leading biomarker study mandatory.
• Previous clinical trial experience, industry experience is preferred.
• Strong knowledge on Biomarker evaluation, esp. in immunology and infections, type I diabetes, relevant parameters and underlying biology.
• Good knowledge of statistical programming languages including R (Bioconductor package and other relevant R packages for genetic data), Python.
• Analysis of high-dimensional data.

Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.

No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment.

Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities.